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The map label for this gene is mmuP [H]

Identifier: 152968882

GI number: 152968882

Start: 348873

End: 350282

Strand: Direct

Name: mmuP [H]

Synonym: KPN_00309

Alternate gene names: 152968882

Gene position: 348873-350282 (Clockwise)

Preceding gene: 152968873

Following gene: 152968883

Centisome position: 6.56

GC content: 61.13

Gene sequence:

>1410_bases
ATGCAAAGCACAACACAACAACAAGGTGGGCAGCTGAAGCGCACCATGAAAACGCGCCATCTGATCATGCTGTCGCTCGG
CGGCGTGATTGGCACCGGCTTATTCTTTAATACCGGCTATATCATCTCCACCACCGGCGCGGCCGGGACGCTGCTGGCGT
ATCTGATTGGCGCCCTGGTGGTCTGGCTGGTGATGCAGTGCCTTGGCGAACTGTCGGTGGCGATGCCAGAGACCGGCGCC
TTCCACGTTTACGCGGCGCGCTATCTTGGCCCGGCGACGGGCTATACCGTGGCGTGGCTCTACTGGCTAACGTGGACGGT
GGCGCTGGGGTCGAGCTTCACCGCGGCGGGATTCTGCATGCAGTACTGGTTCCCGCAGGTGCCGGTCTGGATCTGGTGCG
TGGTGTTCTGCGCAGTGATCTTCGGCCTTAACATCATTTCGACGCGCTTCTTCGCCGAAGGCGAGTTCTGGTTCTCGCTG
GTGAAAGTGATCACCATCGTCGCGTTTATTATTCTCGGCGGCGCGGCCATTTTCGGCATCATTCCGATGCAGGATGGCTC
CCCGGCGCCGGGCCTGCGCAATATCACCGCCGAAGGCTGGTTCCCGCACGGCGGCCTGCCGATCCTGATGACCATGGTGG
CGGTGAACTTCGCCTTCTCCGGGACGGAGCTTATCGGCATTGCCGCCGGAGAGACGGAAAACCCGCATAAGGTTATTCCG
GTTGCCATCCGCACCACCATCGCCCGGCTGATTATTTTCTTTATCGGCACCGTGTTTGTGCTGGCGGCGCTGATCCCGAT
GCAGCAGGCGGGAGTGGAGAAAAGCCCCTTCGTGCTGGTGTTTGAGAAGGTGGGCATCCCTTATGCGGCGGACATGTTCA
ACTTCGTGATCCTGACGGCGATCCTGTCGGCGGCTAACTCCGGCCTGTACGCTTCCGGGCGGATGCTGTGGTCGCTGTCG
AACGAGAAGACGCTGCCGGCCTGCTTTGCCAAAGTCAATAAACGGGGCGTGCCGGTGACCGCCCTGTCGGTGAGTATGCT
GGGCGGCGTGCTGGCGCTGTTCTCCAGCGTGGTGGCGCCAGATACGGTGTTTGTCGCGCTGTCGGCGATCTCCGGTTTTG
CGGTGGTGGCGGTGTGGTTGAGCATCTGCGCCTCGCACTTTATGTTCCGCCGCCGCCATCTGCAGCAGGGTAAGGCGCTG
AGCGATCTCCAGTATCGCGCTCCCTGGTATCCGGTGGTGCCCGTTCTGGGCTTTGTGCTGTGCCTGGTGGCCTGCGTGGG
CCTCGCTTTTGACCCGAGCCAGAGAATTGCGCTGTGGTGCGGGATCCCCTTTGTGGCCCTGTGCTATGGTGCCTGGTATC
TTACTCGTTCACGGAATATGACTCAGGAGCCCCAACATGTCGCAGACTAA

Upstream 100 bases:

>100_bases
AGCGGCGGCACGGTATAACACTTCTTCTTTTGGATGTTTAGATGTCTATACGTTTATACGCAGCATGACCCGGGCAAGCG
GGCTGGCGTGAGAAAATAAA

Downstream 100 bases:

>100_bases
TCCGTTTACCGCCCTGCTTGACGCCCAGCCTTTCGTGCTGCTGGACGGCGCCATGGCCACCGAGCTGGAGGCCCGCGGCT
GCGATCTGGCCGACAGCCTG

Product: S-methylmethionine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MQSTTQQQGGQLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVWLVMQCLGELSVAMPETGA
FHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCMQYWFPQVPVWIWCVVFCAVIFGLNIISTRFFAEGEFWFSL
VKVITIVAFIILGGAAIFGIIPMQDGSPAPGLRNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPHKVIP
VAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADMFNFVILTAILSAANSGLYASGRMLWSLS
NEKTLPACFAKVNKRGVPVTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRRHLQQGKAL
SDLQYRAPWYPVVPVLGFVLCLVACVGLAFDPSQRIALWCGIPFVALCYGAWYLTRSRNMTQEPQHVAD

Sequences:

>Translated_469_residues
MQSTTQQQGGQLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVWLVMQCLGELSVAMPETGA
FHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCMQYWFPQVPVWIWCVVFCAVIFGLNIISTRFFAEGEFWFSL
VKVITIVAFIILGGAAIFGIIPMQDGSPAPGLRNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPHKVIP
VAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADMFNFVILTAILSAANSGLYASGRMLWSLS
NEKTLPACFAKVNKRGVPVTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRRHLQQGKAL
SDLQYRAPWYPVVPVLGFVLCLVACVGLAFDPSQRIALWCGIPFVALCYGAWYLTRSRNMTQEPQHVAD
>Mature_469_residues
MQSTTQQQGGQLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVWLVMQCLGELSVAMPETGA
FHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCMQYWFPQVPVWIWCVVFCAVIFGLNIISTRFFAEGEFWFSL
VKVITIVAFIILGGAAIFGIIPMQDGSPAPGLRNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPHKVIP
VAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADMFNFVILTAILSAANSGLYASGRMLWSLS
NEKTLPACFAKVNKRGVPVTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRRHLQQGKAL
SDLQYRAPWYPVVPVLGFVLCLVACVGLAFDPSQRIALWCGIPFVALCYGAWYLTRSRNMTQEPQHVAD

Specific function: Transporter for the intake of S-methylmethionine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=376, Percent_Identity=22.8723404255319, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI258614005, Length=391, Percent_Identity=22.7621483375959, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI258614003, Length=391, Percent_Identity=22.7621483375959, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081708, Length=469, Percent_Identity=92.5373134328358, Blast_Score=880, Evalue=0.0,
Organism=Escherichia coli, GI1788480, Length=480, Percent_Identity=38.125, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1786302, Length=466, Percent_Identity=36.480686695279, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI48994972, Length=443, Percent_Identity=37.020316027088, Blast_Score=274, Evalue=7e-75,
Organism=Escherichia coli, GI1786602, Length=455, Percent_Identity=35.3846153846154, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1786789, Length=428, Percent_Identity=35.2803738317757, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI87081915, Length=450, Percent_Identity=33.7777777777778, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1789017, Length=432, Percent_Identity=34.7222222222222, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1790653, Length=472, Percent_Identity=31.9915254237288, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI2367353, Length=410, Percent_Identity=25.1219512195122, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081869, Length=399, Percent_Identity=25.062656641604, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082250, Length=351, Percent_Identity=23.3618233618234, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=444, Percent_Identity=20.7207207207207, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320772, Length=427, Percent_Identity=32.7868852459016, Blast_Score=239, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6320717, Length=451, Percent_Identity=31.9290465631929, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324061, Length=427, Percent_Identity=31.615925058548, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324553, Length=406, Percent_Identity=34.4827586206897, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6319824, Length=452, Percent_Identity=30.0884955752212, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324059, Length=427, Percent_Identity=33.0210772833724, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6324990, Length=480, Percent_Identity=30.2083333333333, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6321629, Length=431, Percent_Identity=29.4663573085847, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6319543, Length=436, Percent_Identity=30.045871559633, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6321053, Length=411, Percent_Identity=29.4403892944039, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6319542, Length=440, Percent_Identity=28.6363636363636, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322892, Length=417, Percent_Identity=29.9760191846523, Blast_Score=186, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320251, Length=424, Percent_Identity=27.3584905660377, Blast_Score=182, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324924, Length=412, Percent_Identity=29.8543689320388, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322967, Length=412, Percent_Identity=28.8834951456311, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324981, Length=412, Percent_Identity=30.5825242718447, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6319608, Length=437, Percent_Identity=23.5697940503432, Blast_Score=142, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=489, Percent_Identity=23.5173824130879, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24667468, Length=413, Percent_Identity=22.2760290556901, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50793; Mature: 50793

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTTQQQGGQLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALV
CCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEECCHHHHHHHHHHHHHH
VWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCM
HHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QYWFPQVPVWIWCVVFCAVIFGLNIISTRFFAEGEFWFSLVKVITIVAFIILGGAAIFGI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
IPMQDGSPAPGLRNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPHKVIP
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEH
VAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADMFNFVILTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
ILSAANSGLYASGRMLWSLSNEKTLPACFAKVNKRGVPVTALSVSMLGGVLALFSSVVAP
HHHHCCCCCEECCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DTVFVALSAISGFAVVAVWLSICASHFMFRRRHLQQGKALSDLQYRAPWYPVVPVLGFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHCCCCCCHHHHHHHHH
CLVACVGLAFDPSQRIALWCGIPFVALCYGAWYLTRSRNMTQEPQHVAD
HHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure
MQSTTQQQGGQLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALV
CCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEECCHHHHHHHHHHHHHH
VWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCM
HHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QYWFPQVPVWIWCVVFCAVIFGLNIISTRFFAEGEFWFSLVKVITIVAFIILGGAAIFGI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
IPMQDGSPAPGLRNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPHKVIP
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEH
VAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADMFNFVILTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
ILSAANSGLYASGRMLWSLSNEKTLPACFAKVNKRGVPVTALSVSMLGGVLALFSSVVAP
HHHHCCCCCEECCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DTVFVALSAISGFAVVAVWLSICASHFMFRRRHLQQGKALSDLQYRAPWYPVVPVLGFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHCCCCCCHHHHHHHHH
CLVACVGLAFDPSQRIALWCGIPFVALCYGAWYLTRSRNMTQEPQHVAD
HHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9882684 [H]