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The map label for this gene is dinB [H]

Identifier: 152968821

GI number: 152968821

Start: 279293

End: 280381

Strand: Direct

Name: dinB [H]

Synonym: KPN_00247

Alternate gene names: 152968821

Gene position: 279293-280381 (Clockwise)

Preceding gene: 152968819

Following gene: 152968822

Centisome position: 5.25

GC content: 57.85

Gene sequence:

>1089_bases
ATGCTGTATGGGTATACAGTGTTGAGTCTGACGATGCGTAAAATTATCCATGTCGATATGGACTGTTTCTTTGCGGCGGT
GGAGATGCGCGACAACCCAGCGTTGCGCGATATTCCCCTCGCGATAGGCGGCAGTCGGGTACAACGTGGCGTGATTAGTA
CCGCGAACTATCCTGCGCGTAAGTTTGGCGTGCGCAGCGCCATGCCGACGGCGACGGCGCTCAAGCTGTGCCCGCACCTC
ACGCTGCTTCCTGGCCGCTTCGATGCCTACAAAGAAGCCTCGAACCATATCCGCGAAATTTTCTCCCGCTATACCTCGCG
CATTGAGCCGCTGTCGCTGGATGAAGCCTATCTTGACGTCAGCGACAGCGAGCATTGTCACGGGTCAGCCACCCTGATAG
CCCAGGAGATCCGCCAGACCATCGAACGGGAGCTGCGCCTCACCGCCTCGGCGGGGGTGGCGCCGGTGAAGTTTCTCGCT
AAAATCGCTTCAGATATGAATAAACCCAACGGCCAGTTCGTTATCGCTCCCCATCAGGTGGCAGAGTTTGTGCGGGCGCT
GCCGCTGGCGAAAATACCCGGCGTCGGGAAGGTATCGGCAGCGAAGCTGGAAAATATGGGCCTGCGAACCTGTGGCGATG
TGCAAAACAGCGATCTGGCCATGCTGCTTAAGCGCTTCGGTAAATTCGGGCGTATTCTGTGGGAGCGCAGCCACGGGATT
GATGAGCGGGAAATTCATAACGATCGGCAGCGTAAATCGGTGGGCGTGGAGCGCACCTTAGCGGAAGATATCCATGAATG
GCCGGAGTGCGAAGCGATTATCGAAAACCTCTATCCCGAGCTGGAGAGGCGACTGGCGAAGGTCAAACCTGATCTGCTGA
TCGCCCGCCAGGGCATTAAACTGAAATTCAATGATTTCCAGCTGACCACCCAGGAGCACGTCTGGCCGCGGCTGAACAAA
GAGGATCTGATCGCCACCGCGCACAAAGCCTGGGATGAGCGCCGCGGCGGACGGGGCGTGCGCCTGGTTGGGCTCCACGT
GACGTTGCTCGATCCGCAGCTGGAAAGGCAGCTTTTATTAGGGATTTAG

Upstream 100 bases:

>100_bases
AACTCAATGAAAATAAACATAATTTATTACAGTTTTATGTTTTAACCGCTTTTTTAGCCGATGAAATAAAAAAAGCATAA
AATTCGCATCTGTTTTTGCT

Downstream 100 bases:

>100_bases
CCATGCATATTCGTGCTTACCGCGACAGCGATTTGCCACTGCTCTGCCAGATCTTTCTGCGCGCGGTGCGGGAAACCGCC
AGTCGGGACTATACCCCGGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLYGYTVLSLTMRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHL
TLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLA
KIASDMNKPNGQFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGI
DEREIHNDRQRKSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNK
EDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLLGI

Sequences:

>Translated_362_residues
MLYGYTVLSLTMRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHL
TLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLA
KIASDMNKPNGQFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGI
DEREIHNDRQRKSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNK
EDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLLGI
>Mature_362_residues
MLYGYTVLSLTMRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRVQRGVISTANYPARKFGVRSAMPTATALKLCPHL
TLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVSDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLA
KIASDMNKPNGQFVIAPHQVAEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGI
DEREIHNDRQRKSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIKLKFNDFQLTTQEHVWPRLNK
EDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLLGI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=29.9382716049383, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=29.8461538461538, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI154350220, Length=253, Percent_Identity=32.0158102766798, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=49.5327102803738, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI5729982, Length=119, Percent_Identity=42.0168067226891, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=88.034188034188, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=25.6880733944954, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=409, Percent_Identity=30.8068459657702, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17537959, Length=289, Percent_Identity=29.757785467128, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=354, Percent_Identity=25.7062146892655, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=351, Percent_Identity=23.6467236467236, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19923006, Length=327, Percent_Identity=30.5810397553517, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.0353356890459, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.0353356890459, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=35.2941176470588, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40822; Mature: 40822

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYGYTVLSLTMRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRVQRGVISTANYPAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCCCHH
KFGVRSAMPTATALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDV
HHCCHHCCCHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCC
SDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNGQFVIAPHQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHH
AEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGI
HHHHHHCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DEREIHNDRQRKSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIK
CHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
LKFNDFQLTTQEHVWPRLNKEDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLL
EEECCEEECHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHC
GI
CC
>Mature Secondary Structure
MLYGYTVLSLTMRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRVQRGVISTANYPAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCCCHH
KFGVRSAMPTATALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDV
HHCCHHCCCHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCC
SDSEHCHGSATLIAQEIRQTIERELRLTASAGVAPVKFLAKIASDMNKPNGQFVIAPHQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHH
AEFVRALPLAKIPGVGKVSAAKLENMGLRTCGDVQNSDLAMLLKRFGKFGRILWERSHGI
HHHHHHCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DEREIHNDRQRKSVGVERTLAEDIHEWPECEAIIENLYPELERRLAKVKPDLLIARQGIK
CHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
LKFNDFQLTTQEHVWPRLNKEDLIATAHKAWDERRGGRGVRLVGLHVTLLDPQLERQLLL
EEECCEEECHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHC
GI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA