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The map label for this gene is nqrE

Identifier: 152968817

GI number: 152968817

Start: 276033

End: 276629

Strand: Direct

Name: nqrE

Synonym: KPN_00243

Alternate gene names: 152968817

Gene position: 276033-276629 (Clockwise)

Preceding gene: 152968816

Following gene: 152968818

Centisome position: 5.19

GC content: 57.62

Gene sequence:

>597_bases
ATGGCTCATTACATCAGCCTGTTTGTCCGCGCGGTGTTCGTTGAGAACATGGCGCTGGCCTTCTTCCTCGGGATGTGCAC
CTTTCTTGCGGTGTCGAAAAAGGTCTCCACCGCCTCCGGCCTCGGCGTCGCGGTGACGGTAGTGCTGGGGCTTGCCGTGC
CAATCAATAACCTGGTCTATAACCTGGTGCTGCGCGACGGCGCGCTGGTTGAGGGGGTGGATCTCAGCTTTCTTAACTTC
ATCACCTTTATCGGAGTGATCGCCGCGCTGGTGCAGATCCTCGAGATGATCCTCGATAAGTATTTTCCGGCACTGTACAA
CGCGCTGGGCATCTTCCTGCCGCTGATTGCGGTTAACTGTGCGATTTTCGGCGGCGTGTCGTTCATGGTGCAGCGCGATT
ACAACTTCCCGGAGTCCATCGTCTACGGCTTCGGCTCCGGCATTGGCTGGATGCTGGCGATCGTGGCGATGGCGGGGATC
CGCGAAAAAATGAAGTACGCCAACGTGCCTGCCGGTTTGCGCGGGTTAGGGATCACCTTTATCACCACCGGACTAATGGC
GCTGGGCTTTATGTCCTTCTCCGGCGTGCAGCTATAA

Upstream 100 bases:

>100_bases
CCTGTTCCTGCTGGCGCCGAGCGCGTTCTTCATTATCGGTTTGCTGATCTGGGCCCTGCGTAGCTGGAAGCCTGAGCAGC
AGGAAAAGGAGTAATCGGTG

Downstream 100 bases:

>100_bases
GGGCGAATAAGTATGGAAATTATTCTTGGCGTCGTGATGTTCACGCTGATTGTGCTGGTGCTGTCGGGGCTTATCCTGGC
AGCGCGCTCAAAGCTGGTGA

Product: Na(+)-translocating NADH-quinone reductase subunit E

Products: NA

Alternate protein names: Na(+)-NQR subunit E; Na(+)-translocating NQR subunit E; NQR complex subunit E; NQR-1 subunit E

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAHYISLFVRAVFVENMALAFFLGMCTFLAVSKKVSTASGLGVAVTVVLGLAVPINNLVYNLVLRDGALVEGVDLSFLNF
ITFIGVIAALVQILEMILDKYFPALYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGIGWMLAIVAMAGI
REKMKYANVPAGLRGLGITFITTGLMALGFMSFSGVQL

Sequences:

>Translated_198_residues
MAHYISLFVRAVFVENMALAFFLGMCTFLAVSKKVSTASGLGVAVTVVLGLAVPINNLVYNLVLRDGALVEGVDLSFLNF
ITFIGVIAALVQILEMILDKYFPALYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGIGWMLAIVAMAGI
REKMKYANVPAGLRGLGITFITTGLMALGFMSFSGVQL
>Mature_197_residues
AHYISLFVRAVFVENMALAFFLGMCTFLAVSKKVSTASGLGVAVTVVLGLAVPINNLVYNLVLRDGALVEGVDLSFLNFI
TFIGVIAALVQILEMILDKYFPALYNALGIFLPLIAVNCAIFGGVSFMVQRDYNFPESIVYGFGSGIGWMLAIVAMAGIR
EKMKYANVPAGLRGLGITFITTGLMALGFMSFSGVQL

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG2209

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787914, Length=196, Percent_Identity=44.3877551020408, Blast_Score=150, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRE_KLEP7 (A6T525)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001333926.1
- STRING:   A6T525
- GeneID:   5339135
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_00243
- eggNOG:   COG2209
- HOGENOM:   HBG624915
- OMA:   FLGMCSF
- ProtClustDB:   PRK02830
- HAMAP:   MF_00429
- InterPro:   IPR003667
- InterPro:   IPR010967
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01940

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 21231; Mature: 21100

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x139f80b8)-; HASH(0x45704978)-; HASH(0x45702608)-; HASH(0x13c4d49c)-; HASH(0x13b3cd48)-; HASH(0x13b46b10)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHYISLFVRAVFVENMALAFFLGMCTFLAVSKKVSTASGLGVAVTVVLGLAVPINNLVY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NLVLRDGALVEGVDLSFLNFITFIGVIAALVQILEMILDKYFPALYNALGIFLPLIAVNC
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQRDYNFPESIVYGFGSGIGWMLAIVAMAGIREKMKYANVPAGLRGLGITF
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ITTGLMALGFMSFSGVQL
HHHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
AHYISLFVRAVFVENMALAFFLGMCTFLAVSKKVSTASGLGVAVTVVLGLAVPINNLVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NLVLRDGALVEGVDLSFLNFITFIGVIAALVQILEMILDKYFPALYNALGIFLPLIAVNC
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFGGVSFMVQRDYNFPESIVYGFGSGIGWMLAIVAMAGIREKMKYANVPAGLRGLGITF
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ITTGLMALGFMSFSGVQL
HHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA