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The map label for this gene is cdsA [H]

Identifier: 152968769

GI number: 152968769

Start: 221518

End: 222300

Strand: Direct

Name: cdsA [H]

Synonym: KPN_00188

Alternate gene names: 152968769

Gene position: 221518-222300 (Clockwise)

Preceding gene: 152968768

Following gene: 152968770

Centisome position: 4.17

GC content: 59.39

Gene sequence:

>783_bases
ATGGGCTTTGCTATCGTCACCCTGGTGGTCTGTATGCTCGCCGCCTGGGAGTGGGGACAACTGAGCGGTTTTACCTCGAC
GTCGCAGCGGGTTTGGCTGGCGGTGCTGTGCGGCCTTCTGCTGGCGGCGATGCTTTTTCTGCTGCCTGAATACCATTATG
ACGTTCATCAACCGATGGTTGAAGGGTCGCTATGGGCCTCTTTTGCCTGGTGGATCGTCGCGTTACTGCTGGTGCTCTCA
TACCCGGCGTCGGCGGCATTCTGGCGCCACTCTAAGGTGCTGCGCCTCATCTTCGGCATTCTGACCATCGTCCCGTTTTT
CTGGGGCATGCTGGCGCTGCGCGCCTGGCACTATGCCGATAACCACTACAGCGGCGCGCTGTGGCTGCTGTACGTCATGA
TCCTGGTGTGGGGCGCGGACTCTGGCGCCTATATGTTTGGTAAAATGTTTGGCAAGCACAAGCTGGCGCCGAAGGTCTCA
CCGGGTAAAACCTGGCAGGGCTTTTTTGGCGGTTTGCTGACCGCGGCAGTGATTTCCTGGGCCTACGGCGTGTGGGCCCA
TCTTGACGTCACGCCGACGGTGCTGCTGGTTTGTTCGGTGGTGGCGGCCCTGGCTTCGGTGCTGGGCGACCTGACGGAAA
GTATGTTTAAGCGCGAGGCCGGCATTAAGGATAGCGGGCACTTGATTCCCGGACATGGTGGTATTCTCGATCGTATCGAC
AGCCTGACGGCGGCGGTACCGGTCTTCGCCTGTCTGCTACTGTTGGTCTTCAGGACGATTTGA

Upstream 100 bases:

>100_bases
CAGTCATGCCTGATGGGGGTCACTTTTGCTGAAGTATCGCCTGATATCTGCTTTCGTCTTAATCCCCATCGTCATTGCGG
CATTGTTTTTATTGCCGCCG

Downstream 100 bases:

>100_bases
CGGAAGGTTATATGCTGAGCGTGCTCTGGAATCTGGCGGCTTTTATCATTGCGCTTGGCGTACTGATTACGGTGCATGAG
TTTGGCCATTTTTGGGTGGC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDVHQPMVEGSLWASFAWWIVALLLVLS
YPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMILVWGADSGAYMFGKMFGKHKLAPKVS
PGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRID
SLTAAVPVFACLLLLVFRTI

Sequences:

>Translated_260_residues
MGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDVHQPMVEGSLWASFAWWIVALLLVLS
YPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMILVWGADSGAYMFGKMFGKHKLAPKVS
PGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRID
SLTAAVPVFACLLLLVFRTI
>Mature_259_residues
GFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDVHQPMVEGSLWASFAWWIVALLLVLSY
PASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMILVWGADSGAYMFGKMFGKHKLAPKVSP
GKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDS
LTAAVPVFACLLLLVFRTI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=260, Percent_Identity=87.6923076923077, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1787677, Length=110, Percent_Identity=44.5454545454545, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28664; Mature: 28533

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDVHQPMV
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGSLWASFAWWIVALLLVLSYPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYAD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NHYSGALWLLYVMILVWGADSGAYMFGKMFGKHKLAPKVSPGKTWQGFFGGLLTAAVISW
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRID
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
SLTAAVPVFACLLLLVFRTI
HHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]