Click here to switch to the map view.

The map label for this gene is cysG

Identifier: 151222729

GI number: 151222729

Start: 2767458

End: 2768063

Strand: Reverse

Name: cysG

Synonym: NWMN_2517

Alternate gene names: 151222729

Gene position: 2768063-2767458 (Counterclockwise)

Preceding gene: 151222730

Following gene: 151222728

Centisome position: 96.15

GC content: 37.13

Gene sequence:

>606_bases
ATGAATATGCCATTAATGATAGATTTAACAAATAAAAATGTCGTCATAGTTGGTGGAGGCGTCGTTGCAAGTCGTCGGGC
ACAAACATTAAATCAATACGTTGAACATATGACGGTCATCAGTCCGACAATCACTGAAAAACTTCAAAATATGGTAGATA
ACGGTGTCGTCATATGGAAAGAAAAAGAATTTGAACCAAGCGATATTGTAGACGCGTATCTAGTTATTGCAGCAACCAAT
GAGCCACGTGTCAATGAAGCGGTAAAAAAAGCCTTACCTGAGCATGCCCTTTTTAATAATGTTGGAGATGCATCAAATGG
CAATGTTGTATTTCCAAGTGCACTACACCGCGACAAGCTAACTATCAGTGTATCAACTGATGGTGCGAGTCCTAAGTTGA
CAAAATCAATTATGGCAGAGCTTGAGGCGTTATATCCACCATCATACAGTTCGTATATCGACTTTTTATATACTTGCCGA
CAGAAAATAAAAGTACTTGATATAACATATAACGAAAAGCAACAGTTACTGTCACAAATTGTGTCACAAGAATATTTAAA
TCATGACAAACAAGCTCAATTTTTAGCGTGGTTGGATGTAAGATAA

Upstream 100 bases:

>100_bases
TGAAACAACAACAACGCTATCAACGTGATGTTTATTAGCGATTGGTGTTAAATATTTTAAGGTGTAATGATGTAAAAAGA
TATAAAGGATGTTGCTCAAC

Downstream 100 bases:

>100_bases
TAATAGCGGACCGTCTAACCGTCTAAGGTAAGTCTTCTTATTTTAACTTTAACGCTTAATCATTGAAATTAAGACATGGG
CGGCTTTGTGAATAGTCTAA

Product: precorrin-2 dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKKALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR

Sequences:

>Translated_201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKKALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR
>Mature_201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKKALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR

Specific function: Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin used as precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis [H]

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789768, Length=197, Percent_Identity=27.4111675126904, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: NA

EC number: =1.3.1.76 [H]

Molecular weight: Translated: 22542; Mature: 22542

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWK
CCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
EKEFEPSDIVDAYLVIAATNEPRVNEAVKKALPEHALFNNVGDASNGNVVFPSALHRDKL
CCCCCCHHHHEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCCEE
TISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCRQKIKVLDITYNEKQQLLSQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHH
VSQEYLNHDKQAQFLAWLDVR
HHHHHHCCCCHHEEEEEEECC
>Mature Secondary Structure
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWK
CCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
EKEFEPSDIVDAYLVIAATNEPRVNEAVKKALPEHALFNNVGDASNGNVVFPSALHRDKL
CCCCCCHHHHEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCCEE
TISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCRQKIKVLDITYNEKQQLLSQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHH
VSQEYLNHDKQAQFLAWLDVR
HHHHHHCCCCHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA