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The map label for this gene is fnbB

Identifier: 151222609

GI number: 151222609

Start: 2636113

End: 2638146

Strand: Reverse

Name: fnbB

Synonym: NWMN_2397

Alternate gene names: 151222609

Gene position: 2638146-2636113 (Counterclockwise)

Preceding gene: 151222610

Following gene: 151222608

Centisome position: 91.64

GC content: 35.1

Gene sequence:

>2034_bases
GTGAAAAGCAATCTTAGATACGGCATAAGAAAACACAAATTGGGAGCGGCCTCAGTATTCTTAGGAACAATGATCGTTGT
TGGAATGGGACAAGAAAAAGAAGCTGCAGCATCGGAACAAAACAATACTACAGTAGAGGAAAGTGGGAGTTCAGCTACTG
AAAGTAAAGCAAGCGAAACACAAACAACTACAAATAACGTTAATACAATAGATGAAACACAATCATACAGCGCGACATCA
ACTGAGCAACCATCACAATCAACACAAGTAACAACAGAAGAAGCACCGAAAACTGTGCAAGCACCAAAAGTAGAAACTTC
GCGAGTTGATTTGCCATCGGAAAAAGTTGCTGATAAGGAAACTACAGGAACTCAAGTTGACATAGCTCAACCAAGTAACG
TCTCAGAAATTAAACCAAGAATGAAAAGATCAACTGACGTTACAGCAGTTGCAGAGAAAGAAGTAGTGGAAGAAACTAAA
GCGACAGGTACAGATGTAACAAATAAAGTGGAAGTAGAAGAAGGTAGTGAAATTGTAGGACATAAACAAGATACGAATGT
TGTAAATCCTCATAACGCAGAAAGAGTAACCTTGAAATATAAATGGAAATTTGGAGAAGGAATTAAGGCGGGAGATTATT
TTGATTTCACATTAAGCGATAATGTTGAAACTCATGGTATCTCAACACTGCGTAAAGTTCCGGAGATAAAAAGTACAGAT
GGTCAAGTTATGGCGACAGGAGAAATAATTGGAGAAAGAAAAGTTAGATATACGTTTAAAGAATATGTACAAGAAAAGAA
AGATTTAACTGCTGAATTATCTTTAAATCTATTTATTGATCCTACAACAGTGACGCAAAAAGGTAACCAAAATGTTGAAG
TTAAATTGGGTGAGACTACGGTTAGCAAAATATTTAATATTCAATATTTAGGTGGAGTTAGAGATAATTGGGGAGTAACA
GCTAATGGTCGAATTGATACTTTAAATAAAGTAGATGGGAAATTTAGTCATTTTGCGTACATGAAACCTAACAACCAGTC
GTTAAGCTCTGTGACAGTAACTGGTCAAGTAACTAAAGGAAATAAACCAGGGGTTAATAATCCAACAGTTAAGGTATATA
AACACATTGGTTCAGACGATTTAGCTGAAAGCGTATATGCAAAGCTTGATGATGTCAGCAAATTTGAAGATGTGACTGAT
AATATGAGTTTAGATTTTGATACTAATGGTGGTTATTCTTTAAACTTTAATAATTTAGACCAAAGTAAAAATTATGTAAT
AAAATATGAAGGGTATTATGATTCAAATGCTAGCAACTTAGAATTTCAAACACACCTTTTTGGATATTATAACTATTATT
ATACAAGTAATTTAACTTGGAAAAATGGCGTTGCATTTTACTCTAATAACGCTCAAGGCGACGGCAAAGATAAACTAAAG
GAACCTATTATAGAACATAGTACTCCTATCGAACTTGAATTTAAATCAGAGCCGCCAGTGGAGAAGCATGAATTGACTGG
TACAATCGAAGAAAGTAATGATTCTAAGCCAATTGATTTTGAATATCATACAGCTGTTGAAGGTGCAGAAGGTCATGCAG
AAGGTACCATTGAAACTGAAGAAGATTCTATTCATGTAGACTTTGAAGAATCGACACATGAAAATTCAAAACATCATGCT
GATGTTGTTGAATATGAAGAAGATACAAACCCAGGTGGTGGTCAGGTTACTACTGAGTCTAACCTAGTTGAATTTGACGA
AGATTCTACAAAAGGTATTGTAACTGGTGCTGTTAGCGATCATACAACAATTGAAGATACGAAAGAATATACGACTGAAA
GTAATCTGATTGAACTAGTAGATGAACTACCTGAAGAACATGGTCAAGCGCAAGGACCAATCGAGGAAATTACTGAAAAC
AATCATCATATTTCTCATTCTGGTTTAGGAACTGAAAATGGTCACGGTAATTATGGCGTGATTGAAGAAATCGAAGAAAA
TAGCCACGTGGATATTAAGAGTGAATTAGGTTAG

Upstream 100 bases:

>100_bases
ACTCGCTTTTTTTCATTGCTTTTAAAAACCGAACAATATAGAATTGCATTTATTGAGTTTTAAAAATAAATGAATTTTGC
ATTTAAGGGAGAATATTATA

Downstream 100 bases:

>100_bases
GAAGGTGGCCAAAATAGCGGTAATCAGTCATTTGAGGAAGACACAGAAGAAGATAAACCGAAATATGAACAAGGTGGCAA
TATCGTAGATATCGATTTCG

Product: fibronectin binding protein B precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELG

Sequences:

>Translated_677_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELG
>Mature_677_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELG

Specific function: Promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin. This confers to S.aureus the ability to invade endothelial cells. Promotes adherence to and aggregation of activated platel

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011266
- InterPro:   IPR008966
- InterPro:   IPR011252
- InterPro:   IPR004237
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02986 Fn_bind; PF00746 Gram_pos_anchor; PF10425 SdrG_C_C; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 74738; Mature: 74738

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASET
CCCCCCCCHHHHCCCHHHHHHHHHHEEECCCCHHHHCCCCCCCCHHCCCCCCHHHHCCCC
QTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETKATGTDVTNKVEVEEGSEIVG
CCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
HKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHHCHHHHHHCCCCCCCC
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETT
CCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEECCCCCEEEEEECCHH
VSKIFNIQYLGGVRDNWGVTANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKG
HHHHEEEEEECCCCCCCCEEECCCCCCHHHCCCCCCEEEEECCCCCCCEEEEEEEEEECC
NKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTDNMSLDFDTNGGYSLNFNNLD
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
QSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
CCCCEEEEECCEECCCCCCEEEEEEEEEEEEEEEECCCEECCCEEEEECCCCCCCHHHHH
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETE
HHHHHCCCCEEEEECCCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEC
EDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSD
CCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCCEEEEECCCC
HTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGV
CCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCH
IEEIEENSHVDIKSELG
HHHHCCCCCEEEHHCCC
>Mature Secondary Structure
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASET
CCCCCCCCHHHHCCCHHHHHHHHHHEEECCCCHHHHCCCCCCCCHHCCCCCCHHHHCCCC
QTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETKATGTDVTNKVEVEEGSEIVG
CCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
HKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHHCHHHHHHCCCCCCCC
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETT
CCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEECCCCCEEEEEECCHH
VSKIFNIQYLGGVRDNWGVTANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKG
HHHHEEEEEECCCCCCCCEEECCCCCCHHHCCCCCCEEEEECCCCCCCEEEEEEEEEECC
NKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTDNMSLDFDTNGGYSLNFNNLD
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
QSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
CCCCEEEEECCEECCCCCCEEEEEEEEEEEEEEEECCCEECCCEEEEECCCCCCCHHHHH
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETE
HHHHHCCCCEEEEECCCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEC
EDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSD
CCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCCEEEEECCCC
HTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGV
CCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCH
IEEIEENSHVDIKSELG
HHHHCCCCCEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA