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The map label for this gene is sepA

Identifier: 151222281

GI number: 151222281

Start: 2305522

End: 2305995

Strand: Reverse

Name: sepA

Synonym: NWMN_2069

Alternate gene names: 151222281

Gene position: 2305995-2305522 (Counterclockwise)

Preceding gene: 151222282

Following gene: 151222280

Centisome position: 80.1

GC content: 27.0

Gene sequence:

>474_bases
ATGATTGTGAATTATCTTAAACATAAGTTTTATAACTTGTTAACTACAATGATTGTTCTCTTTATTTTTGTACTTTCTGG
TGCGATTTTTTTAACATTTCTAGGGTTTGGTTTATATGGATTAAGTAGAATACTTATTTATTTTAGGTTGGGTGACTTTA
CATATAATAGAAGTATGTACGATAACCTATTATATTATGGCAGTTATATAATCTTTGGGTACTTCATCATATTTGCAGTC
GAGCATTTAATGGATTATTTTAGAAAAATGTTGCCTGAAAATGCATATTTTAGAGGCGCGACTTTTCATTTGATTTCTTA
CACAGTTGCAACAACGTTATTTTATTTTATTATTCATCTGAACTATGTGTATATCAATATCGATTTTTGGGTCATCATGG
TTATTATAGGGTTCTTATATGTTTGTAAGCTTCAATTTTACCCTGAAAGTAAAAATTTAAATAATAGAAAATAG

Upstream 100 bases:

>100_bases
AGAATTATGATTAAAATTGATGTAGTGTAATTAAAGTAAGAAATAATAAATTTCCTAGATACTAGATAAATCGTTCAATA
TTTTATTAATAAGGAGGCCA

Downstream 100 bases:

>100_bases
ATATCTGAAGTTGAGGGCACATATGTGTTCCAACTTCTTTTTGTTCAATAGAAGAATCGATAATAGTGAGTCTTAGTGCT
CAATTTGTGGTAAATAAGTT

Product: hypothetical protein

Products: NA

Alternate protein names: Antiseptic resistance protein sepA; Staphylococcal efflux pump A

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAV
EHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK

Sequences:

>Translated_157_residues
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAV
EHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>Mature_157_residues
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAV
EHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK

Specific function: Involved in multidrug efflux

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multidrug resistance efflux pump sepA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDEP_STAA1 (A7X534)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442741.1
- STRING:   A7X534
- EnsemblBacteria:   EBSTAT00000002770
- GeneID:   5559042
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2151
- eggNOG:   NOG47990
- GeneTree:   EBGT00050000024548
- HOGENOM:   HBG535516
- OMA:   FYPDSEN
- ProtClustDB:   CLSK885806
- BioCyc:   SAUR418127:SAHV_2151-MONOMER
- GO:   GO:0006810

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18900; Mature: 18900

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b3785d0)-; HASH(0x1b271a7c)-; HASH(0x1a22f374)-; HASH(0x1b37d268)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA