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The map label for this gene is tig

Identifier: 151221781

GI number: 151221781

Start: 1736086

End: 1737387

Strand: Reverse

Name: tig

Synonym: NWMN_1569

Alternate gene names: 151221781

Gene position: 1737387-1736086 (Counterclockwise)

Preceding gene: 151221782

Following gene: 151221780

Centisome position: 60.35

GC content: 33.87

Gene sequence:

>1302_bases
ATGACAGCAACTTGGGAAAAAAAGGAAGGTAACGAAGGTTTATTAACTGTTACTGTTCCTGCAGAAAAAGTAAACAAAGC
GTTAGATCAAGCATTCAAAAAAGTGGTTAAACAAATTAACGTACCTGGATTCCGTAAAGGTAAAGTGCCACGTCCAATTT
TTGAACAACGCTTTGGTGTAGAAGCATTATATCAAGATGCTATCGACATTTTATTACCAGATGCTTATGGTGAAGCAATT
GACGAAACTGATATTAAACCAGTTGCACAACCAGAAGTAAGTGTTACTCAAATTGAAAAAGGTAAAGATTTCATTTTTGA
AGCAACAGTTACAGTTGAGCCAGAAGTTAAATTAGGAGACTATAAAGGTCTTGAAATTGAAAAACAAGAAACTGAATTAT
CTGATGATGAGTTACAAGAAGCGATTGACCACAGCTTAGGACATTTAGCTGAAATGGTCGTTAAAGAAGATGGTGTTGTT
GAAAATGGCGACACAGTTAACATCGACTTTAGTGGTTCAGTTGACGGAGAAGAATTCGAAGGTGGACAAGCTGAAGGTTA
CGATTTAGAAATCGGTTCAGGTTCATTCATACCTGGTTTCGAAGAGCAATTAGAAGGTATGAAAGTTGACGAAGAAAAAG
ATGTTGTCGTAACATTCCCAGAAGAATACCATGCTGAAGAATTAGCCGGTAAAGAAGCAACTTTCAAAACAAAAGTTAAC
GAAATTAAATTTAAAGAAGTCCCAGAATTAACAGATGAAATTGCTAATGAATTAGATGCAGAAGCAAATACAGTAGACGA
GTACAAAGAAAACTTACGTAAACGTTTAGCTGAACAAAAAGCTACAGATGCTGAAAATGTTGAAAAAGAAGAAGCGATTA
CAAAAGCTACTGATAATACAACAATCGATATTCCTGAAGCAATGATTAATACTGAATTAGATCGTATGGTGTCTGAATTT
GCACAAAGAATTCAACAACAAGGTTTAGATTTACAAACGTACTTCCAAATCTCAGGTCAAGATGAAACTCAATTAAGAGA
GCAAATGAAAGACGATGCAGAACAACGTGTTAAAACTAACTTAACTTTAACTGCGATCGCTGAAGCTGAAAAAATCGAAG
CTACTGATGAAGATATCGATAAAGAATTAGAAAAAATGAGTAAACAATTTAATATCTCAGTTGAAGATATCAAAAATACT
TTAGGTAATACTGATATCATTAAAAATGATGTTCGTATCCAAAAAGTTATCGATTTATTAAGAGATAACGCAAAGTTCGT
TGAAGGAACTAAAGAAGATTAA

Upstream 100 bases:

>100_bases
TATATAAACGTTGTGATTTCAATGTTTGTATAGGGAATAGACCTATGATATAATAGGGAAGTTGAAAAAATAAATTAGTT
AATCATGGAGGTATATATAC

Downstream 100 bases:

>100_bases
TCTTCATTAAATATTAAATTACAAAAATGAGTAGCAGATGCATAGCTTATGTATCTGCTACTATTCTTTAAGCAAAAAGT
TTGTATGTTAATATGTTGCA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAI
DETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVV
ENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVN
EIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMINTELDRMVSEF
AQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNT
LGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED

Sequences:

>Translated_433_residues
MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAI
DETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVV
ENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVN
EIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMINTELDRMVSEF
AQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNT
LGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
>Mature_432_residues
TATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAID
ETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVE
NGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNE
IKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMINTELDRMVSEFA
QRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTL
GNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=412, Percent_Identity=32.5242718446602, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48623; Mature: 48492

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGV
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCH
EALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGD
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCEEECC
YKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFE
CCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCCCCC
GGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVN
CCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHH
EIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
TIDIPEAMINTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTN
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
LTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLL
CEEEEEHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RDNAKFVEGTKED
HCCCHHCCCCCCC
>Mature Secondary Structure 
TATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGV
CCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCH
EALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGD
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCEEECC
YKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFE
CCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCCCCC
GGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVN
CCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHH
EIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
TIDIPEAMINTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTN
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
LTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLL
CEEEEEHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RDNAKFVEGTKED
HCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA