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The map label for this gene is ptsG [H]

Identifier: 151220389

GI number: 151220389

Start: 229587

End: 231122

Strand: Reverse

Name: ptsG [H]

Synonym: NWMN_0177

Alternate gene names: 151220389

Gene position: 231122-229587 (Counterclockwise)

Preceding gene: 151220410

Following gene: 151220387

Centisome position: 8.03

GC content: 39.26

Gene sequence:

>1536_bases
ATGTTGATGAAATCTTTATTTGAAAAAGCACAGCAGTTCGGCAAGTCCTTTATGTTACCTATCGCAATCTTACCAGCTGC
AGGTCTATTGTTGGGTATCGGTGGTGCATTAAGTAATCCAAACACCGTTAAAGCATACCCTATTTTAGATATTACCTTAT
TACAAAATATTTTTACATTAATGTCAGCTGCAGGTAGTATTGTTTTCCAAAATTTACCGGTCATCTTTGCAATTGGTGTC
GCAATCGGATTATCTAGAAGCGATAAAGGTACTGCAGGTTTAGCTGCGCTGCTCGGTTTCTTAATTATGAACGCAACTAT
GAATGGCTTATTAACTATCACGGGCACATTGGCAAAAGATCAGCTTGCACAAAATGGACAAGGCATGGTGCTCGGTATAC
AAACGGTTGAAACCGGTGTTTTTGGCGGGATTATCACAGGTATTATGACCGCAATACTTCACAACAAATATCACAAAGTG
GTATTACCACCGTATTTAGGTTTCTTTGGTGGCTCTAGATTTGTCCCTATTGTCACAGCATTTGCCGCAATCTTTTTAGG
TGTATTGATGTTTTTCATTTGGCCAAGCATACAAGCCGGCATTTATCATGTTGGTGGATTTGTAACGAAAACAGGTGCCA
TCGGTACTTTTGTTTATGGCTTCATCTTAAGATTGTTAGGTCCACTCGGTTTACACCATATTTTTTACTTACCGTTTTGG
CAGACGGCACTTGGTGGTACTTTAGAAGTCAAAGGGCACTTAGTTCAAGGTACGCAGAACATCTTCTTTGCTCAACTTGG
TGATCCAGATGTGACGAAGTATTATTCAGGTGTGTCACGCTTTATGTCAGGCCGTTTTATTACGATGATGTTCGGCTTAT
GTGGTGCCGCACTTGCAATTTATCACACAGCTAAACCTGAACATAAAAAAGTTGTCGGCGGTTTAATGTTATCCGCTGCA
CTCACTTCATTTTTAACAGGTATTACCGAACCTTTAGAGTTTAGTTTCTTGTTTGTCGCACCTATTCTTTATGTAATCCA
TGCCTTCTTTGATGGATTAGCATTTATGATGGCAGACATTTTCAACATTACAATTGGTCAAACCTTCAGTGGAGGCTTTA
TCGATTTCTTACTCTTTGGTGTGCTACAAGGTAATAGTAAAACAAACTACCTATACGTCATACCTATTGGAATTGTGTGG
TTCTGTTTGTATTACATCGTTTTCAGATTCTTAATTACGAAATTTAATTTCAAAACACCTGGTCGAGAAGATAAAGCTGC
AGCACAACAAGTTGAGGCTACTGAAAGAGCACAAACTATTGTTGCTGGTTTGGGAGGCAAAGATAACATTGAAATCGTTG
ACTGTTGTGCAACGAGACTACGCGTCACACTTCATCAAAATGACAAAGTCGATAAAGTATTACTCGAAAGTACTGGTGCC
AAAGGTGTAATCCAGCAAGGCACTGGTGTGCAAGTAATTTATGGGCCTCACGTTACAGTTATCAAAAATGAAATTGAAGA
ATTGCTCGGGGATTAA

Upstream 100 bases:

>100_bases
GTTACATGATTCAAACAATTTTTATGAAAAATATTTTCATACACAGAATATATATTGATATTAAATTTCTCAAAAGCTAT
ATTGAGAATAATTAGGAGGG

Downstream 100 bases:

>100_bases
GACTAACCGAAATATCAACAGAACTAATGGCAACGATGTACGAAGTAAGAAGTGACATCGTTGCTTTTATTTTTAATGTT
ACATTTGAAGCATTAAGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MLMKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGV
AIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKV
VLPPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFW
QTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAA
LTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVW
FCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLHQNDKVDKVLLESTGA
KGVIQQGTGVQVIYGPHVTVIKNEIEELLGD

Sequences:

>Translated_511_residues
MLMKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGV
AIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKV
VLPPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFW
QTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAA
LTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVW
FCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLHQNDKVDKVLLESTGA
KGVIQQGTGVQVIYGPHVTVIKNEIEELLGD
>Mature_511_residues
MLMKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGV
AIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKV
VLPPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFW
QTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAA
LTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVW
FCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLHQNDKVDKVLLESTGA
KGVIQQGTGVQVIYGPHVTVIKNEIEELLGD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=518, Percent_Identity=40.9266409266409, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1787343, Length=513, Percent_Identity=42.495126705653, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1786894, Length=512, Percent_Identity=35.3515625, Blast_Score=272, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55179; Mature: 55179

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHH
MSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKD
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHH
QLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKVVLPPYLGFFGGSRFVPIVTA
HHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCHHHHHHH
FAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFW
HHHHHHHHHHHHHHHHHHHCHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAI
HHHCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
YHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADI
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVWFCLYYIVFRFLITKFNFKTP
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLHQNDKVDKVLLESTGA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHCCCC
KGVIQQGTGVQVIYGPHVTVIKNEIEELLGD
CCEEECCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLMKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHH
MSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKD
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHH
QLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKVVLPPYLGFFGGSRFVPIVTA
HHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCHHHHHHH
FAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFW
HHHHHHHHHHHHHHHHHHHCHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAI
HHHCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
YHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADI
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVWFCLYYIVFRFLITKFNFKTP
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLHQNDKVDKVLLESTGA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHCCCC
KGVIQQGTGVQVIYGPHVTVIKNEIEELLGD
CCEEECCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA