Click here to switch to the map view.

The map label for this gene is speB [C]

Identifier: 150401868

GI number: 150401868

Start: 1502892

End: 1503731

Strand: Direct

Name: speB [C]

Synonym: Maeo_1446

Alternate gene names: 150401868

Gene position: 1502892-1503731 (Clockwise)

Preceding gene: 150401863

Following gene: 150401869

Centisome position: 95.76

GC content: 30.36

Gene sequence:

>840_bases
ATGTATTTTGAAGATTTTTCTAAATTTATATGCGCTTATGATGATTTTGAAGATAGTTTATATACAATATTCGGAGCTCC
ATATGATGGTACAACATCATATAAGCCAGGGGCAAGATTTGGAGCAGATGAGATAAGAAAAGCATCATGGGGATTGGAGA
CATATAGCCCAATATTAAAAAAGGATTTGGTTGATGTTCCCATATGTGATTTACACAACATATCCGTAGATGGAACTCAA
AAGGATATTATGAAGTATATATATGAGGCATCAAAAAATTCAATGAAAAACAATAAAATACCAATTATGCTGGGAGGAGA
GCATTCTATAACTTACCCAGTAGTAAAATCGGCAAAAAAAAAATATGATGATATATTATTAATTCAATTTGATGCCCACT
GCGATTTAAGGGAGAATTATTTGAATAATAAATATTCTCATGCAAGTGTGATAAGAAGGTGCTTTGATTTAACAAAAGAT
ATATATCAATTTGGAATAAGAAGTGGAGATGAAGAGGAATGGGAATTCGGAGAAAAAAACACAAATATTAGTATGGAGCT
CCCAACAAAAGAAGACATAAATATAATAAAAGAATTAGATAAAAAAATATATATAACAATAGATATAGATGTTTTAGACC
CTGCCTTTGCCCCGGGAACTGGAACACCAGAGCCATGCGGATTTTCTTCAAAAGAATTAATGAATTCATTATATTTATTT
AAAGAATTAAAAGACAATATCATAGGTTTTGATGTTGTTGAGGTTTCACCGCATTATGATGCTGGAAATATTACTTCAAT
TATGGGGGCAAAAATAGTGAGAGAATTAATTTTATTATAA

Upstream 100 bases:

>100_bases
ATTAGATAATATTTTAAATAATATTTAATAATTATTTATAATATTATATTATTATATTTTGGTTATGATTTTATAATTTA
TATAATATTATGGTGGTCAA

Downstream 100 bases:

>100_bases
GGCGATAAAATGGACAATAATAAAGATAAAAATAACAAAACAGAAAGCACCGTAAATATAGGAATAGTAGTTCATGGACC
AGAAATAATTGATTCAGGTA

Product: putative agmatinase

Products: putrescine; urea

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MYFEDFSKFICAYDDFEDSLYTIFGAPYDGTTSYKPGARFGADEIRKASWGLETYSPILKKDLVDVPICDLHNISVDGTQ
KDIMKYIYEASKNSMKNNKIPIMLGGEHSITYPVVKSAKKKYDDILLIQFDAHCDLRENYLNNKYSHASVIRRCFDLTKD
IYQFGIRSGDEEEWEFGEKNTNISMELPTKEDINIIKELDKKIYITIDIDVLDPAFAPGTGTPEPCGFSSKELMNSLYLF
KELKDNIIGFDVVEVSPHYDAGNITSIMGAKIVRELILL

Sequences:

>Translated_279_residues
MYFEDFSKFICAYDDFEDSLYTIFGAPYDGTTSYKPGARFGADEIRKASWGLETYSPILKKDLVDVPICDLHNISVDGTQ
KDIMKYIYEASKNSMKNNKIPIMLGGEHSITYPVVKSAKKKYDDILLIQFDAHCDLRENYLNNKYSHASVIRRCFDLTKD
IYQFGIRSGDEEEWEFGEKNTNISMELPTKEDINIIKELDKKIYITIDIDVLDPAFAPGTGTPEPCGFSSKELMNSLYLF
KELKDNIIGFDVVEVSPHYDAGNITSIMGAKIVRELILL
>Mature_279_residues
MYFEDFSKFICAYDDFEDSLYTIFGAPYDGTTSYKPGARFGADEIRKASWGLETYSPILKKDLVDVPICDLHNISVDGTQ
KDIMKYIYEASKNSMKNNKIPIMLGGEHSITYPVVKSAKKKYDDILLIQFDAHCDLRENYLNNKYSHASVIRRCFDLTKD
IYQFGIRSGDEEEWEFGEKNTNISMELPTKEDINIIKELDKKIYITIDIDVLDPAFAPGTGTPEPCGFSSKELMNSLYLF
KELKDNIIGFDVVEVSPHYDAGNITSIMGAKIVRELILL

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=278, Percent_Identity=34.1726618705036, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1789306, Length=276, Percent_Identity=29.3478260869565, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325146, Length=211, Percent_Identity=28.436018957346, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: 3.5.3.11

Molecular weight: Translated: 31812; Mature: 31812

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFEDFSKFICAYDDFEDSLYTIFGAPYDGTTSYKPGARFGADEIRKASWGLETYSPILK
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHH
KDLVDVPICDLHNISVDGTQKDIMKYIYEASKNSMKNNKIPIMLGGEHSITYPVVKSAKK
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHH
KYDDILLIQFDAHCDLRENYLNNKYSHASVIRRCFDLTKDIYQFGIRSGDEEEWEFGEKN
CCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
TNISMELPTKEDINIIKELDKKIYITIDIDVLDPAFAPGTGTPEPCGFSSKELMNSLYLF
CCEEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KELKDNIIGFDVVEVSPHYDAGNITSIMGAKIVRELILL
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYFEDFSKFICAYDDFEDSLYTIFGAPYDGTTSYKPGARFGADEIRKASWGLETYSPILK
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHH
KDLVDVPICDLHNISVDGTQKDIMKYIYEASKNSMKNNKIPIMLGGEHSITYPVVKSAKK
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHH
KYDDILLIQFDAHCDLRENYLNNKYSHASVIRRCFDLTKDIYQFGIRSGDEEEWEFGEKN
CCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
TNISMELPTKEDINIIKELDKKIYITIDIDVLDPAFAPGTGTPEPCGFSSKELMNSLYLF
CCEEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KELKDNIIGFDVVEVSPHYDAGNITSIMGAKIVRELILL
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: agmatine; H2O

Specific reaction: agmatine + H2O = putrescine + urea

General reaction: Amidine hydrolysis [C]

Inhibitor: EDTA; EGTA [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]