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The map label for this gene is cysS

Identifier: 150401798

GI number: 150401798

Start: 1439378

End: 1440817

Strand: Reverse

Name: cysS

Synonym: Maeo_1376

Alternate gene names: 150401798

Gene position: 1440817-1439378 (Counterclockwise)

Preceding gene: 150401800

Following gene: 150401797

Centisome position: 91.8

GC content: 29.58

Gene sequence:

>1440_bases
ATGAAAATTTACAACACTGCATCAAAAAATAAGGAAACATTTAAAACTATCAATAATAAAAAACTAATAAAAATGTATGT
TTGCGGACCTACTGTATATGACCATGCCCATTTAGGACATGGGCGAACTTATGTAGCTTTTGACATAATTAGAAGATATT
TAGAACATAAAAATTATATTGTTCAATTAATTATAAATTTTACAGATATTGATGATAAAATTATAAATCGTGCAAATGAA
CAGGGAACAACCATTAAAGAATTATCGGATAAATTTATAAACTCCTTTTTAGAGGATATGGAAAAATTGAATGTTAAACC
TGCCTTAATATACCCAAGAGTTTCAGAACATATAAATGAGATAATTGAATTTATAAAAGTTCTTGAAAAAAAAGGATATG
CCTACGCCACAGCCGATGGAGTTTATTTTGATACCTCAAAATATGAAAAATATGGGGAGCTCCGAAAAATAAACATCAAA
GAAGAGACTTCCGAACAAAAAAATATAAATATAAATAAAAAAAATCAACGAGATTTTGCCCTTTGGAAATTTGCCAAACC
AGATGAGCCAAAATGGGATAGCCCATGGGGAGAAGGAAGACCTGCGTGGCATATTGAATGCTCTGCTATGAGTTTAAAGT
ATTTGGGGGATAATTTTGACATTCACGGCGGAGGATGTGATTTAATATTCCCCCACCACGAAAACGAAAAGGCACAAAGT
GAATGTTATACTGATAAAAAATGGGTAAATTATTGGATCCATACGGGATTTGTGATGGTAAATAATGAAAAAATGAGCAA
AAGTTTGGGGAATTTCTCTACTCTTAAAGATTTATTTGAAAAATATTCTGCTGAATTAATTAGATTTTTCCTATTAGAAC
GGCATTACAGCTCCCCACTGGATTATACAGAGGACGCCATAAATCACTCCAAAAATAATTTGGACAAATTATATAATACC
ATACAAAATATAACCGTAGCATTTAGAAATTCAGAAATAAAATATAAATTAAATGAAATAGATAAAAATACAATTGAAAC
AATACATAATTGCACAGAAAAATTTTATACTGCCATGGACGATAATTTTAACACCGCTCAGGCTCTTAAATATGTTTTTG
AAGTATCTACTGCCATAAATAAATATATAAATAATTATGCTAATTCCGATGAATTGCCAAATTACAGCATAATATTAAAA
TCCTATGAATTTTTTAAAATGGTTGGGGAAATATTTGGCATATTTGGGAGCTCCACCATAAACACTGCAACAAATACAAA
TATCGCAGAGGAAAATTTAATAAATATTTTGATGGAGCTCCGTGCAGATTTAAAAAAAGAAAAAAATTATAATTTATCCG
ACAAAATAAGGGATAAATTAAAAGAAATGGATATTATTTTAGAGGATAGTCCAAAGGGAACAATTTGGAAAAAGGCATAA

Upstream 100 bases:

>100_bases
ATTATAATTTATATATATGTATTTTATGTTATCTATATTATATATTATCCATACTATTATATATTATCATATATCATTTT
ATAATATTATCGGGGAAATT

Downstream 100 bases:

>100_bases
AATGAAATATAAAACAATTAAAAAATTGGGAAACTCAGAAAAAATATTTAAAAATTCAATATTTTTGGGATATGCTTCAC
CAATAAATAGTGAAGAAGAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKIYNTASKNKETFKTINNKKLIKMYVCGPTVYDHAHLGHGRTYVAFDIIRRYLEHKNYIVQLIINFTDIDDKIINRANE
QGTTIKELSDKFINSFLEDMEKLNVKPALIYPRVSEHINEIIEFIKVLEKKGYAYATADGVYFDTSKYEKYGELRKINIK
EETSEQKNININKKNQRDFALWKFAKPDEPKWDSPWGEGRPAWHIECSAMSLKYLGDNFDIHGGGCDLIFPHHENEKAQS
ECYTDKKWVNYWIHTGFVMVNNEKMSKSLGNFSTLKDLFEKYSAELIRFFLLERHYSSPLDYTEDAINHSKNNLDKLYNT
IQNITVAFRNSEIKYKLNEIDKNTIETIHNCTEKFYTAMDDNFNTAQALKYVFEVSTAINKYINNYANSDELPNYSIILK
SYEFFKMVGEIFGIFGSSTINTATNTNIAEENLINILMELRADLKKEKNYNLSDKIRDKLKEMDIILEDSPKGTIWKKA

Sequences:

>Translated_479_residues
MKIYNTASKNKETFKTINNKKLIKMYVCGPTVYDHAHLGHGRTYVAFDIIRRYLEHKNYIVQLIINFTDIDDKIINRANE
QGTTIKELSDKFINSFLEDMEKLNVKPALIYPRVSEHINEIIEFIKVLEKKGYAYATADGVYFDTSKYEKYGELRKINIK
EETSEQKNININKKNQRDFALWKFAKPDEPKWDSPWGEGRPAWHIECSAMSLKYLGDNFDIHGGGCDLIFPHHENEKAQS
ECYTDKKWVNYWIHTGFVMVNNEKMSKSLGNFSTLKDLFEKYSAELIRFFLLERHYSSPLDYTEDAINHSKNNLDKLYNT
IQNITVAFRNSEIKYKLNEIDKNTIETIHNCTEKFYTAMDDNFNTAQALKYVFEVSTAINKYINNYANSDELPNYSIILK
SYEFFKMVGEIFGIFGSSTINTATNTNIAEENLINILMELRADLKKEKNYNLSDKIRDKLKEMDIILEDSPKGTIWKKA
>Mature_479_residues
MKIYNTASKNKETFKTINNKKLIKMYVCGPTVYDHAHLGHGRTYVAFDIIRRYLEHKNYIVQLIINFTDIDDKIINRANE
QGTTIKELSDKFINSFLEDMEKLNVKPALIYPRVSEHINEIIEFIKVLEKKGYAYATADGVYFDTSKYEKYGELRKINIK
EETSEQKNININKKNQRDFALWKFAKPDEPKWDSPWGEGRPAWHIECSAMSLKYLGDNFDIHGGGCDLIFPHHENEKAQS
ECYTDKKWVNYWIHTGFVMVNNEKMSKSLGNFSTLKDLFEKYSAELIRFFLLERHYSSPLDYTEDAINHSKNNLDKLYNT
IQNITVAFRNSEIKYKLNEIDKNTIETIHNCTEKFYTAMDDNFNTAQALKYVFEVSTAINKYINNYANSDELPNYSIILK
SYEFFKMVGEIFGIFGSSTINTATNTNIAEENLINILMELRADLKKEKNYNLSDKIRDKLKEMDIILEDSPKGTIWKKA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=481, Percent_Identity=34.9272349272349, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI62240992, Length=410, Percent_Identity=32.9268292682927, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI303304987, Length=410, Percent_Identity=32.9268292682927, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI21269877, Length=410, Percent_Identity=32.9268292682927, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI10835051, Length=410, Percent_Identity=32.9268292682927, Blast_Score=214, Evalue=1e-55,
Organism=Escherichia coli, GI1786737, Length=486, Percent_Identity=40.1234567901235, Blast_Score=376, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17509795, Length=447, Percent_Identity=31.9910514541387, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17509797, Length=447, Percent_Identity=31.9910514541387, Blast_Score=197, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6324082, Length=329, Percent_Identity=39.5136778115502, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=34.1269841269841, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI19922364, Length=345, Percent_Identity=33.6231884057971, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_META3 (A6UWT0)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325564.1
- ProteinModelPortal:   A6UWT0
- SMR:   A6UWT0
- STRING:   A6UWT0
- GeneID:   5327234
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1376
- eggNOG:   arNOG04368
- HOGENOM:   HBG327651
- OMA:   VVKIYCC
- ProtClustDB:   PRK00260
- BioCyc:   MAEO419665:MAEO_1376-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_A
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 56018; Mature: 56018

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYNTASKNKETFKTINNKKLIKMYVCGPTVYDHAHLGHGRTYVAFDIIRRYLEHKNYI
CCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
VQLIINFTDIDDKIINRANEQGTTIKELSDKFINSFLEDMEKLNVKPALIYPRVSEHINE
EEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
IIEFIKVLEKKGYAYATADGVYFDTSKYEKYGELRKINIKEETSEQKNININKKNQRDFA
HHHHHHHHHHCCCEEEECCCEEEECHHHHHCCCEEEECCHHHCCHHHCCCCCCCCCCCEE
LWKFAKPDEPKWDSPWGEGRPAWHIECSAMSLKYLGDNFDIHGGGCDLIFPHHENEKAQS
EEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEECCCCEEEECCCCCCCHHHH
ECYTDKKWVNYWIHTGFVMVNNEKMSKSLGNFSTLKDLFEKYSAELIRFFLLERHYSSPL
HHCCCHHHHHHEEEECEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DYTEDAINHSKNNLDKLYNTIQNITVAFRNSEIKYKLNEIDKNTIETIHNCTEKFYTAMD
CHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCEEEEHHHCCHHHHHHHHHHHHHHHHHHC
DNFNTAQALKYVFEVSTAINKYINNYANSDELPNYSIILKSYEFFKMVGEIFGIFGSSTI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCC
NTATNTNIAEENLINILMELRADLKKEKNYNLSDKIRDKLKEMDIILEDSPKGTIWKKA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKIYNTASKNKETFKTINNKKLIKMYVCGPTVYDHAHLGHGRTYVAFDIIRRYLEHKNYI
CCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
VQLIINFTDIDDKIINRANEQGTTIKELSDKFINSFLEDMEKLNVKPALIYPRVSEHINE
EEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
IIEFIKVLEKKGYAYATADGVYFDTSKYEKYGELRKINIKEETSEQKNININKKNQRDFA
HHHHHHHHHHCCCEEEECCCEEEECHHHHHCCCEEEECCHHHCCHHHCCCCCCCCCCCEE
LWKFAKPDEPKWDSPWGEGRPAWHIECSAMSLKYLGDNFDIHGGGCDLIFPHHENEKAQS
EEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEECCCCEEEECCCCCCCHHHH
ECYTDKKWVNYWIHTGFVMVNNEKMSKSLGNFSTLKDLFEKYSAELIRFFLLERHYSSPL
HHCCCHHHHHHEEEECEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DYTEDAINHSKNNLDKLYNTIQNITVAFRNSEIKYKLNEIDKNTIETIHNCTEKFYTAMD
CHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCEEEEHHHCCHHHHHHHHHHHHHHHHHHC
DNFNTAQALKYVFEVSTAINKYINNYANSDELPNYSIILKSYEFFKMVGEIFGIFGSSTI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCC
NTATNTNIAEENLINILMELRADLKKEKNYNLSDKIRDKLKEMDIILEDSPKGTIWKKA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA