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The map label for this gene is argC

Identifier: 150401736

GI number: 150401736

Start: 1375378

End: 1376412

Strand: Reverse

Name: argC

Synonym: Maeo_1314

Alternate gene names: 150401736

Gene position: 1376412-1375378 (Counterclockwise)

Preceding gene: 150401737

Following gene: 150401735

Centisome position: 87.7

GC content: 32.37

Gene sequence:

>1035_bases
ATGGTTACAATATCCATAATAGGCGGAACAGGATATACGGGAAGTGAATTATTAAGAATACTTTTAAACCACCCCCAAGT
TGAAATAAAGCATATTACTTCTAGAAAAATGGATGGAGTAAATATTACAAAAGTCCATCCAAATTTAAAAAATATTAAAA
ATATTGATAATTTAGTTTTTGAAAATATATCCCCAAGTAATTTGGATTCTGATTTTGTATTTTGTGCCACCCCTCATGGT
GCATCGATGAAAATTGTGCCAGAATTATATGAAACAGGGTCAAAAATAATTGATTTAAGTGGAGATTATAGATTTGAAGA
TTTATCATTATATGAAAAATGGTATAATTTAACTCATACAGGGGAGCTCCCTGCTGTATATGGATTACCAGAATTACATA
GAAATGAAATTAAAAAAGCCCAGTTAGTAGCAAATCCGGGCTGTTTTCCTACTGGTTCAATATTGGCATTAGCCCCACTT
GTAAAAGAGGGAATAATTGAAAATAGGATAATTGTGGATTCAAAAACAGGAGTTAGTGGAGCAGGCGTAAATCCATCGGA
AACAACCCACTATCCAAGCGTAAATGAAAATATATTACCCTACAAAATGACAACCCACAGACATAGCCCAGAAATTGAAA
AAGAGTTGGAAAAATTAAATATATCAAATAATATTAAATTATCATTTACCCCACATTTAGCACCACTTACAAGAGGAATA
TTATCAACAACCCATTCATATTTAAAAAATACAGATATTGATAGGGATATCATTATTGATATTTATAATGAATTCTACAA
AAACGAACCATTTGTAAGAATATTCGAAGAAGGAGCTCCCACGCTAACAGGTGTAAGAGGTTCTAATTTCTGCGATATTG
GTGGTTTTGAAATAGATAGACATGGTAGAATTGTGGTGGTTTCTGCCATAGACAATTTGGTAAAAGGAGCAAGTGGGCAG
GCAATTCATAATTTAAATTTAATGGCCGGATTTAATGAAACAGAAAGCCTATTGTATGGCGGTTTAAAACCATAA

Upstream 100 bases:

>100_bases
CAAACATATTGTAAATCATAGATAAAAAAATAAGATAAAAAAATAAAAATAAATATATAATATAATTTATATATTTATTT
TAAAAAATGGTGATTATTTT

Downstream 100 bases:

>100_bases
TAAACATATTACGACTTTATAACACACACAAACACATATAACATATATACCGATAGGAAAGGAGATAAAATGATATTACA
CCCAAGACCATCTCCAATAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MVTISIIGGTGYTGSELLRILLNHPQVEIKHITSRKMDGVNITKVHPNLKNIKNIDNLVFENISPSNLDSDFVFCATPHG
ASMKIVPELYETGSKIIDLSGDYRFEDLSLYEKWYNLTHTGELPAVYGLPELHRNEIKKAQLVANPGCFPTGSILALAPL
VKEGIIENRIIVDSKTGVSGAGVNPSETTHYPSVNENILPYKMTTHRHSPEIEKELEKLNISNNIKLSFTPHLAPLTRGI
LSTTHSYLKNTDIDRDIIIDIYNEFYKNEPFVRIFEEGAPTLTGVRGSNFCDIGGFEIDRHGRIVVVSAIDNLVKGASGQ
AIHNLNLMAGFNETESLLYGGLKP

Sequences:

>Translated_344_residues
MVTISIIGGTGYTGSELLRILLNHPQVEIKHITSRKMDGVNITKVHPNLKNIKNIDNLVFENISPSNLDSDFVFCATPHG
ASMKIVPELYETGSKIIDLSGDYRFEDLSLYEKWYNLTHTGELPAVYGLPELHRNEIKKAQLVANPGCFPTGSILALAPL
VKEGIIENRIIVDSKTGVSGAGVNPSETTHYPSVNENILPYKMTTHRHSPEIEKELEKLNISNNIKLSFTPHLAPLTRGI
LSTTHSYLKNTDIDRDIIIDIYNEFYKNEPFVRIFEEGAPTLTGVRGSNFCDIGGFEIDRHGRIVVVSAIDNLVKGASGQ
AIHNLNLMAGFNETESLLYGGLKP
>Mature_344_residues
MVTISIIGGTGYTGSELLRILLNHPQVEIKHITSRKMDGVNITKVHPNLKNIKNIDNLVFENISPSNLDSDFVFCATPHG
ASMKIVPELYETGSKIIDLSGDYRFEDLSLYEKWYNLTHTGELPAVYGLPELHRNEIKKAQLVANPGCFPTGSILALAPL
VKEGIIENRIIVDSKTGVSGAGVNPSETTHYPSVNENILPYKMTTHRHSPEIEKELEKLNISNNIKLSFTPHLAPLTRGI
LSTTHSYLKNTDIDRDIIIDIYNEFYKNEPFVRIFEEGAPTLTGVRGSNFCDIGGFEIDRHGRIVVVSAIDNLVKGASGQ
AIHNLNLMAGFNETESLLYGGLKP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=35.8381502890173, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=340, Percent_Identity=32.9411764705882, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_META3 (A6UWL8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325502.1
- ProteinModelPortal:   A6UWL8
- STRING:   A6UWL8
- GeneID:   5326715
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1314
- eggNOG:   arNOG05044
- HOGENOM:   HBG294213
- OMA:   DTKKFME
- ProtClustDB:   PRK00436
- BioCyc:   MAEO419665:MAEO_1314-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38064; Mature: 38064

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTISIIGGTGYTGSELLRILLNHPQVEIKHITSRKMDGVNITKVHPNLKNIKNIDNLVF
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHH
ENISPSNLDSDFVFCATPHGASMKIVPELYETGSKIIDLSGDYRFEDLSLYEKWYNLTHT
CCCCCCCCCCCEEEEECCCCCCEEECHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCC
GELPAVYGLPELHRNEIKKAQLVANPGCFPTGSILALAPLVKEGIIENRIIVDSKTGVSG
CCCCEECCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCC
AGVNPSETTHYPSVNENILPYKMTTHRHSPEIEKELEKLNISNNIKLSFTPHLAPLTRGI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
LSTTHSYLKNTDIDRDIIIDIYNEFYKNEPFVRIFEEGAPTLTGVRGSNFCDIGGFEIDR
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEEECCCEEECC
HGRIVVVSAIDNLVKGASGQAIHNLNLMAGFNETESLLYGGLKP
CCCEEEEEEHHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCC
>Mature Secondary Structure
MVTISIIGGTGYTGSELLRILLNHPQVEIKHITSRKMDGVNITKVHPNLKNIKNIDNLVF
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHH
ENISPSNLDSDFVFCATPHGASMKIVPELYETGSKIIDLSGDYRFEDLSLYEKWYNLTHT
CCCCCCCCCCCEEEEECCCCCCEEECHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCC
GELPAVYGLPELHRNEIKKAQLVANPGCFPTGSILALAPLVKEGIIENRIIVDSKTGVSG
CCCCEECCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCC
AGVNPSETTHYPSVNENILPYKMTTHRHSPEIEKELEKLNISNNIKLSFTPHLAPLTRGI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
LSTTHSYLKNTDIDRDIIIDIYNEFYKNEPFVRIFEEGAPTLTGVRGSNFCDIGGFEIDR
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEEECCCEEECC
HGRIVVVSAIDNLVKGASGQAIHNLNLMAGFNETESLLYGGLKP
CCCEEEEEEHHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA