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The map label for this gene is fixC [C]

Identifier: 150401729

GI number: 150401729

Start: 1367723

End: 1368898

Strand: Reverse

Name: fixC [C]

Synonym: Maeo_1307

Alternate gene names: 150401729

Gene position: 1368898-1367723 (Counterclockwise)

Preceding gene: 150401730

Following gene: 150401727

Centisome position: 87.22

GC content: 34.44

Gene sequence:

>1176_bases
ATGAGAGAATTACTTGATAGTGAATACGATGTTATTGTTATCGGTGCAGGTCCAGGAGGGAGTATGGCATCATATCATTC
GTCAATAAATGGTGCAAAAACCCTATTAATAGATAAATCCCAAGAAATTGGAACTCCGGTTAGATGTGCAGAAGCTGTCC
CATATCTTGATGAATTTGGAATAAATCCCGACCCTTCATTTATTAGGAGTAAAATTGATGGAGGAATATTAGTTGCCCCA
AATGGTAAAAAAATAATTGTTAAAGGAGGAAAAACACAAGGGTATGTTGTAGAAAGAAAAATATTCGACAAACACCTTGC
AGTTAGAAGTGCAAATGTTGGAACTAAAATAGCCATTAAAAGTAGAGTCGTAGGATTAGATTATGATGGCGAAAAATATA
CTGTTATTGTCAATCATCTTGGACAGATATACGCCATAAAAGCAAAAATTGTAATTGCTGCTGATGGTGTTGAAAGCTCA
ATTGCAGAAATGGCAGGAATAAAGTGCAAGAAAAAAGTCACAGAAATATGTTCCTGTGCCGAGTATGAAATGACCAATGT
TAAATTACTTGATAAAAATATGATGGAATTTTATTTCGGAGATATTTGTCCCAAAGGGTATGTGTGGATATTCCCAAAAG
GAGAAACTGCAAATGTAGGTTTGGGAATTATAGACAGTAAAAAGAAAGCCATCGATTACTTAAATGAATTTTTAGAACAT
CCATTGTTGGAAGGAAGGTTGGATAATGCCACACCAATTGAATTTAAATGTGGTGGAGCTCCGGTTGGAGGGCCAATTGA
AAAAACTGTGGCCGATAATTTCATGGTTGTTGGTGATGCCGCTGGGCAAATCAGTCCAATATCTGGCGGAGGTATCTATT
TGTCATTAAGCTGTGGTTCAATTGCAGGAAAAGTTGCGGGAGAAGCCATTAAAAGCAACAATTGTTCAGAAGATTATTTA
GTAGAATATGAAAATAGATGGAAAGAAAAATATTATAAATTATTAATGGATGAATTAAAATATAAAAAAGTTCTTCAAAA
ATTCAGTGAAAAAGAGTTAAATGCTTTGGCAGACGCTATGGATGAAAGATTGGAAGAAATTGATGTGGCAAAAATAGCAT
TTAGAGCGGTGAAAAGGGCACCATCTCTATTAAAATATTTTAAAGATATTATATAA

Upstream 100 bases:

>100_bases
TAGAAAATACAGTTATAATAGATAATGAAAAATGCAACAGTTGCGGACTTTGTGCAATTGTTTGTCCATTAAATGCACTA
AATACTTTGGAGGAGTAAAT

Downstream 100 bases:

>100_bases
AAATTATATAATATTATAATAAGTTCAATAAATGTCCTTTATCTGTCCTAACTTATTATAAATTTCTTCATTTGTTGCGA
TATGATAAAGATTTTAGCTT

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFGINPDPSFIRSKIDGGILVAP
NGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIKSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESS
IAEMAGIKCKKKVTEICSCAEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEH
PLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGSIAGKVAGEAIKSNNCSEDYL
VEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAMDERLEEIDVAKIAFRAVKRAPSLLKYFKDII

Sequences:

>Translated_391_residues
MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFGINPDPSFIRSKIDGGILVAP
NGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIKSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESS
IAEMAGIKCKKKVTEICSCAEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEH
PLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGSIAGKVAGEAIKSNNCSEDYL
VEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAMDERLEEIDVAKIAFRAVKRAPSLLKYFKDII
>Mature_391_residues
MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFGINPDPSFIRSKIDGGILVAP
NGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIKSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESS
IAEMAGIKCKKKVTEICSCAEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEH
PLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGSIAGKVAGEAIKSNNCSEDYL
VEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAMDERLEEIDVAKIAFRAVKRAPSLLKYFKDII

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGR_META3 (A6UWL1)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325495.1
- ProteinModelPortal:   A6UWL1
- SMR:   A6UWL1
- STRING:   A6UWL1
- GeneID:   5327399
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1307
- eggNOG:   arNOG04976
- HOGENOM:   HBG626912
- OMA:   DCGLMAG
- ProtClustDB:   CLSK876233
- BioCyc:   MAEO419665:MAEO_1307-MONOMER
- HAMAP:   MF_01287
- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042
- PRINTS:   PR00420
- TIGRFAMs:   TIGR02032

Pfam domain/function: PF07992 Pyr_redox_2

EC number: NA

Molecular weight: Translated: 42781; Mature: 42781

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFG
CCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHCCCHHHCC
INPDPSFIRSKIDGGILVAPNGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIK
CCCCHHHHHHHCCCCEEECCCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCEEEEE
SRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESSIAEMAGIKCKKKVTEICSCA
EEEEEECCCCCEEEEEECCCCCEEEEEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHC
EYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEH
CCCCCCEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHC
PLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGS
CHHCCCCCCCCCEEEEECCCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCEEEEEECCC
IAGKVAGEAIKSNNCSEDYLVEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAM
HHHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERLEEIDVAKIAFRAVKRAPSLLKYFKDII
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MRELLDSEYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVRCAEAVPYLDEFG
CCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHCCCHHHCC
INPDPSFIRSKIDGGILVAPNGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAIK
CCCCHHHHHHHCCCCEEECCCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCEEEEE
SRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESSIAEMAGIKCKKKVTEICSCA
EEEEEECCCCCEEEEEECCCCCEEEEEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHC
EYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLEH
CCCCCCEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHC
PLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSCGS
CHHCCCCCCCCCEEEEECCCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCEEEEEECCC
IAGKVAGEAIKSNNCSEDYLVEYENRWKEKYYKLLMDELKYKKVLQKFSEKELNALADAM
HHHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERLEEIDVAKIAFRAVKRAPSLLKYFKDII
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA