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The map label for this gene is 150401676

Identifier: 150401676

GI number: 150401676

Start: 1317505

End: 1318950

Strand: Reverse

Name: 150401676

Synonym: Maeo_1254

Alternate gene names: NA

Gene position: 1318950-1317505 (Counterclockwise)

Preceding gene: 150401681

Following gene: 150401674

Centisome position: 84.04

GC content: 29.94

Gene sequence:

>1446_bases
ATGGACAATATAACAATTGATTATTCAATATTGAATAAATATTCATTATGTCACAGATGTTTTGGTAGATTATATGCAAA
ATCGCTACATACTACCAATTACGAGAGGGGGAGAGCATTGAAAATGGCTAAGGCTATTGAATTAGAGCTAAATTTAGCTA
ATTTATATAATCTATTAAATGGATTGAATGAACTAAATGAAAATAGCAATGATATAGGAGAAATAAAAGAAACAGAAGAA
GATATAATAAAAGAAATAGAAATAAAGAAAGAAGAACTAAAAAACATATACAAAAGTGGATTAATCGAAATAACCAATAT
GGTGGAAAATATAGAGGAAATAAAAGAAACGGAAGAAACCACCAATGAAAATGAAAAAAAATATTCCTGTCCATATTGTA
GAGATATATTTGATAAAAATCATTTAAATGACATCTCCGAAAAAATATTAAAATTTACAAGTAATTATGAATTCGACACT
TTTTTAATAGGGACAGTACTCCCTAAAAAGATAAAAGAGTTAGAAAAAGAAATTATAAACGATAACCCAATGGCAGAAAG
TATAAAACAAGAATTTAACAGAATGATGGGAAAAATGATAGTGGAAAAAACCAATAAAGTTGTGGAAAAAACCAATCCTG
ATATTGTAATAATGGTTAATCCATACAATAAAAGAATAGAATTACAAATAAATTCTATATTCATTAAGGGAAGATATAAT
AAATTAATAAGGGGCATACCACAATCCCACTGGCATTGTAGGAGTTGCAGAGGAAAGGGATGCGAAAAATGCGATTGGAC
TGGTAAGCAATATCCGACCTCAGTTGAAGAGATAATAGCAGAACCATTTATGAAGGCATTTAAAGGAAAAGAAGAAGCCT
TCCATGGTGCAGGGAGGGAGGATATAGATGTTAGAATGTTAGGAAATGGGAGGCCTTTTGTGCTTCAAATAAAAGAGCCA
AAAATAAGAAAAGCCGATTTAAAACCACTAATGGAGGAAGTAAATAAAAGTGGAAAAGTTGAAATCCATAATTTAGAATA
TGGAGTTAGAAAGGATATCATATTTTTTAAAAATGAGGCACATAGAAAAACATATTTAGCCCATGTGGAATGTGAAGATG
AAATCACAGAAGATGAAATCAAACAATTAGTGGAACAGATGCAAAATCTTACAATAAATCAGAGAACCCCTCAAAGAGTA
AGTCACAGAAGGGCAGATTTAATAAGAGTTAGAAATGTTTATGCCGTTTCATTAAATAAAATAATAAATTCAAAAGAATT
TGAACTAAAAATATATTGTGATGGCGGACTATATATTAAAGAATTGATACATGGGGACGAAGGTAGAACGATACCATCTG
TATCGGAGCTCCTAAATAAAAAATGTATATGTAAATTCCTTGATGTATGGGATGTTCATGATTTTGAGCATGAAGAAGAG
CAATAA

Upstream 100 bases:

>100_bases
AACTCACCGGGAGCGTTAAAATTAGAAAATATATAAATAATATATATGTAAATAAATATATAAATAAGTATATAAATAAA
TAGATAAAATAGGTGAAGTT

Downstream 100 bases:

>100_bases
TTTATTTTTACTATATTATTATTTTTCAACCAATTTGGCATCCAATACATTATAATAACCACATTCACAGCTATCATCCC
ATATTATTTCATAATCCATA

Product: putative pseudouridylate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MDNITIDYSILNKYSLCHRCFGRLYAKSLHTTNYERGRALKMAKAIELELNLANLYNLLNGLNELNENSNDIGEIKETEE
DIIKEIEIKKEELKNIYKSGLIEITNMVENIEEIKETEETTNENEKKYSCPYCRDIFDKNHLNDISEKILKFTSNYEFDT
FLIGTVLPKKIKELEKEIINDNPMAESIKQEFNRMMGKMIVEKTNKVVEKTNPDIVIMVNPYNKRIELQINSIFIKGRYN
KLIRGIPQSHWHCRSCRGKGCEKCDWTGKQYPTSVEEIIAEPFMKAFKGKEEAFHGAGREDIDVRMLGNGRPFVLQIKEP
KIRKADLKPLMEEVNKSGKVEIHNLEYGVRKDIIFFKNEAHRKTYLAHVECEDEITEDEIKQLVEQMQNLTINQRTPQRV
SHRRADLIRVRNVYAVSLNKIINSKEFELKIYCDGGLYIKELIHGDEGRTIPSVSELLNKKCICKFLDVWDVHDFEHEEE
Q

Sequences:

>Translated_481_residues
MDNITIDYSILNKYSLCHRCFGRLYAKSLHTTNYERGRALKMAKAIELELNLANLYNLLNGLNELNENSNDIGEIKETEE
DIIKEIEIKKEELKNIYKSGLIEITNMVENIEEIKETEETTNENEKKYSCPYCRDIFDKNHLNDISEKILKFTSNYEFDT
FLIGTVLPKKIKELEKEIINDNPMAESIKQEFNRMMGKMIVEKTNKVVEKTNPDIVIMVNPYNKRIELQINSIFIKGRYN
KLIRGIPQSHWHCRSCRGKGCEKCDWTGKQYPTSVEEIIAEPFMKAFKGKEEAFHGAGREDIDVRMLGNGRPFVLQIKEP
KIRKADLKPLMEEVNKSGKVEIHNLEYGVRKDIIFFKNEAHRKTYLAHVECEDEITEDEIKQLVEQMQNLTINQRTPQRV
SHRRADLIRVRNVYAVSLNKIINSKEFELKIYCDGGLYIKELIHGDEGRTIPSVSELLNKKCICKFLDVWDVHDFEHEEE
Q
>Mature_481_residues
MDNITIDYSILNKYSLCHRCFGRLYAKSLHTTNYERGRALKMAKAIELELNLANLYNLLNGLNELNENSNDIGEIKETEE
DIIKEIEIKKEELKNIYKSGLIEITNMVENIEEIKETEETTNENEKKYSCPYCRDIFDKNHLNDISEKILKFTSNYEFDT
FLIGTVLPKKIKELEKEIINDNPMAESIKQEFNRMMGKMIVEKTNKVVEKTNPDIVIMVNPYNKRIELQINSIFIKGRYN
KLIRGIPQSHWHCRSCRGKGCEKCDWTGKQYPTSVEEIIAEPFMKAFKGKEEAFHGAGREDIDVRMLGNGRPFVLQIKEP
KIRKADLKPLMEEVNKSGKVEIHNLEYGVRKDIIFFKNEAHRKTYLAHVECEDEITEDEIKQLVEQMQNLTINQRTPQRV
SHRRADLIRVRNVYAVSLNKIINSKEFELKIYCDGGLYIKELIHGDEGRTIPSVSELLNKKCICKFLDVWDVHDFEHEEE
Q

Specific function: Unknown

COG id: COG1258

COG function: function code J; Predicted pseudouridylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

Organism=Homo sapiens, GI207113130, Length=253, Percent_Identity=33.201581027668, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17537241, Length=246, Percent_Identity=32.9268292682927, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI19920442, Length=265, Percent_Identity=34.3396226415094, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005912
- InterPro:   IPR020103
- InterPro:   IPR004114 [H]

Pfam domain/function: PF02926 THUMP [H]

EC number: NA

Molecular weight: Translated: 56295; Mature: 56295

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS51165 THUMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNITIDYSILNKYSLCHRCFGRLYAKSLHTTNYERGRALKMAKAIELELNLANLYNLLN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECHHHHHHHHH
GLNELNENSNDIGEIKETEEDIIKEIEIKKEELKNIYKSGLIEITNMVENIEEIKETEET
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNENEKKYSCPYCRDIFDKNHLNDISEKILKFTSNYEFDTFLIGTVLPKKIKELEKEIIN
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
DNPMAESIKQEFNRMMGKMIVEKTNKVVEKTNPDIVIMVNPYNKRIELQINSIFIKGRYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEECCHH
KLIRGIPQSHWHCRSCRGKGCEKCDWTGKQYPTSVEEIIAEPFMKAFKGKEEAFHGAGRE
HHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCC
DIDVRMLGNGRPFVLQIKEPKIRKADLKPLMEEVNKSGKVEIHNLEYGVRKDIIFFKNEA
CCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCC
HRKTYLAHVECEDEITEDEIKQLVEQMQNLTINQRTPQRVSHRRADLIRVRNVYAVSLNK
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IINSKEFELKIYCDGGLYIKELIHGDEGRTIPSVSELLNKKCICKFLDVWDVHDFEHEEE
HHCCCCEEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCC
Q
C
>Mature Secondary Structure
MDNITIDYSILNKYSLCHRCFGRLYAKSLHTTNYERGRALKMAKAIELELNLANLYNLLN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECHHHHHHHHH
GLNELNENSNDIGEIKETEEDIIKEIEIKKEELKNIYKSGLIEITNMVENIEEIKETEET
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNENEKKYSCPYCRDIFDKNHLNDISEKILKFTSNYEFDTFLIGTVLPKKIKELEKEIIN
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
DNPMAESIKQEFNRMMGKMIVEKTNKVVEKTNPDIVIMVNPYNKRIELQINSIFIKGRYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEECCHH
KLIRGIPQSHWHCRSCRGKGCEKCDWTGKQYPTSVEEIIAEPFMKAFKGKEEAFHGAGRE
HHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCC
DIDVRMLGNGRPFVLQIKEPKIRKADLKPLMEEVNKSGKVEIHNLEYGVRKDIIFFKNEA
CCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCC
HRKTYLAHVECEDEITEDEIKQLVEQMQNLTINQRTPQRVSHRRADLIRVRNVYAVSLNK
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IINSKEFELKIYCDGGLYIKELIHGDEGRTIPSVSELLNKKCICKFLDVWDVHDFEHEEE
HHCCCCEEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]