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The map label for this gene is serB [C]

Identifier: 150401476

GI number: 150401476

Start: 1087475

End: 1088107

Strand: Direct

Name: serB [C]

Synonym: Maeo_1052

Alternate gene names: 150401476

Gene position: 1087475-1088107 (Clockwise)

Preceding gene: 150401474

Following gene: 150401477

Centisome position: 69.29

GC content: 31.6

Gene sequence:

>633_bases
ATGAATAAAAAGAAACTAATATTGTTTGACCTTGATAGTACGCTAATAGAAAATGAAACAATTGACGAATTTGCAAAAAT
TACAGGGGTGGAAAATGAAGTAAAGGAAATAACAAAAGATGCAATGAATGGAAAGCTAAATTTTGAACAATCCCTTAAAA
AAAGAGTGGCACTTATAAAGGGAGCTCCCACCAGCAAAATAAAAGAAGCCGTATCTACATTTAAATTAACAGAAGGAGCA
AAAGAGACTATTGAAGAGTTAAAAAATAGAGGGTATATTGTGGGAGTTGTTAGCGGTGGCTTTACTGTGGCAACTGATAA
AATTAAAGAAATGCTTGGTTTGGATTATGCCTACTCCAACAATCTCATAGAAAATGATGGAATATTAACAGGAGAAGTTA
ATGGAGTTATGATGGAGGAACAGGCAAAAGGGAAAATGCTAAAAGAATTGGCAAAAAGGGAAAATATAGATTTAAAAGAT
ACCGTTGTTGTAGGCGATGGAGCAAATGACCTAAGTATGTTTAAAGTGGCAGGTTTTAAAATAGCATTTTGTGCAAAGGA
TATTTTAAAGAAAAATGCCGATATTTGTATAGAAAAAAGAGATTTAAGAGAAATTTTAAAATATATAGAATAA

Upstream 100 bases:

>100_bases
AATTAGGTTTATATCATATATTTTATTATAAATTATACATTTAACATTAAGCAATATGTAGTGTTGTATGTTATATAATA
TTATATTATTTGGTGATTTA

Downstream 100 bases:

>100_bases
AATATATATTAGATGGTCCTATAATTAATATGATAATTAGTGCATATAGTAATTAATATAGGGGTGCATATTAATGAAAA
ATACCAATCTAAAAGACATA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNKKKLILFDLDSTLIENETIDEFAKITGVENEVKEITKDAMNGKLNFEQSLKKRVALIKGAPTSKIKEAVSTFKLTEGA
KETIEELKNRGYIVGVVSGGFTVATDKIKEMLGLDYAYSNNLIENDGILTGEVNGVMMEEQAKGKMLKELAKRENIDLKD
TVVVGDGANDLSMFKVAGFKIAFCAKDILKKNADICIEKRDLREILKYIE

Sequences:

>Translated_210_residues
MNKKKLILFDLDSTLIENETIDEFAKITGVENEVKEITKDAMNGKLNFEQSLKKRVALIKGAPTSKIKEAVSTFKLTEGA
KETIEELKNRGYIVGVVSGGFTVATDKIKEMLGLDYAYSNNLIENDGILTGEVNGVMMEEQAKGKMLKELAKRENIDLKD
TVVVGDGANDLSMFKVAGFKIAFCAKDILKKNADICIEKRDLREILKYIE
>Mature_210_residues
MNKKKLILFDLDSTLIENETIDEFAKITGVENEVKEITKDAMNGKLNFEQSLKKRVALIKGAPTSKIKEAVSTFKLTEGA
KETIEELKNRGYIVGVVSGGFTVATDKIKEMLGLDYAYSNNLIENDGILTGEVNGVMMEEQAKGKMLKELAKRENIDLKD
TVVVGDGANDLSMFKVAGFKIAFCAKDILKKNADICIEKRDLREILKYIE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=186, Percent_Identity=32.7956989247312, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1790849, Length=202, Percent_Identity=38.6138613861386, Blast_Score=140, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI115534454, Length=195, Percent_Identity=32.8205128205128, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534456, Length=195, Percent_Identity=32.8205128205128, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534458, Length=197, Percent_Identity=31.9796954314721, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321647, Length=208, Percent_Identity=37.9807692307692, Blast_Score=131, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24661601, Length=195, Percent_Identity=31.2820512820513, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23362; Mature: 23362

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKLILFDLDSTLIENETIDEFAKITGVENEVKEITKDAMNGKLNFEQSLKKRVALIK
CCCCEEEEEECCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GAPTSKIKEAVSTFKLTEGAKETIEELKNRGYIVGVVSGGFTVATDKIKEMLGLDYAYSN
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCEEEHHHHHHHHHCCCHHHCC
NLIENDGILTGEVNGVMMEEQAKGKMLKELAKRENIDLKDTVVVGDGANDLSMFKVAGFK
CEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCH
IAFCAKDILKKNADICIEKRDLREILKYIE
HHHHHHHHHHCCCCEEECHHHHHHHHHHCC
>Mature Secondary Structure
MNKKKLILFDLDSTLIENETIDEFAKITGVENEVKEITKDAMNGKLNFEQSLKKRVALIK
CCCCEEEEEECCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GAPTSKIKEAVSTFKLTEGAKETIEELKNRGYIVGVVSGGFTVATDKIKEMLGLDYAYSN
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCEEEHHHHHHHHHCCCHHHCC
NLIENDGILTGEVNGVMMEEQAKGKMLKELAKRENIDLKDTVVVGDGANDLSMFKVAGFK
CEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCH
IAFCAKDILKKNADICIEKRDLREILKYIE
HHHHHHHHHHCCCCEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]