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The map label for this gene is 150401471

Identifier: 150401471

GI number: 150401471

Start: 1080252

End: 1081532

Strand: Reverse

Name: 150401471

Synonym: Maeo_1047

Alternate gene names: NA

Gene position: 1081532-1080252 (Counterclockwise)

Preceding gene: 150401472

Following gene: 150401470

Centisome position: 68.91

GC content: 33.49

Gene sequence:

>1281_bases
ATGACTATTGTTAGATTTCACGGAGGATGTCACCAAATTGGTATGTCCTGTGTGGAAATTGATACAAAAAAATCAAAAAT
ACTTGTAGATTGTGGTATGAATCCATCGGATAATTCATTACCAAAAATTAATCCAAATGATATTGATGCCGTTGTGGTGT
CACATTCTCATTTAGACCATTGTGGAGCGGTTCCTTATTTTAATTTTAAAAATCCGATTTATTCCACAATACCAAGTGTT
GATTTAATGTATATTTTATGGAAAGATATTTCAAAATTATCAAAAACATACCCTGAAGAGAATATACAAAAGGCTATGAA
TAATATAAAGGCAGTAAATTACAGAGAGCCTAAAAAAATCACCAGCGATATTACAATGAGGTTGTATGATGCTGGGCATA
TATTGGGGAGCTCCTCTGTATATTTGGACATAGGCGGTAAAAAACTACTATATACTGGAGATATCAACGAAATAGAAACC
AGAACGCTAAAATCAGCCGACACAGATATTGATGAAATTGATACCCTTATAATTGAATCTACCTACGGAGCTCCAACAGA
TATAAAACCATCTAGAAAGGCACTCGAAAAACAACTTATTGATGAAATATCTGCCACCATAGAAAAAGGAGGCAAGGTAA
TTATTCCAGTTTTTGCTGTGGGGCGGTCTCAGGAGATTATAGCGGTATTGCATAATTATATGAGGAGTAAATTATTAAAA
AGAGTTCCCATATATGTTGAAGGCTCTTTGGTGCATACCACAGGAATATATATGAGCCATTCAGAATGGTTAAATCCTAA
AATAAGAAACAACCTTGAAAATAGGATAAATCCATTTGGAGATGTCACCATTGTAAATAAAGAAAATAGTAGTGAAATAT
ATAATAAGGAACCATGCATTATAATTTCTACCTCTGGAATGGTGCAAGGAGGCCCCATATTACAATATTTAAAACTTCTA
AAAAGTCCAAAAAATAAAATAATATTAACAGGGTTCCAAGCAGAAGAGACACTGGGAAGACAGCTTGAAGACGGGGCAGA
GGAAATAACTCCATTTAGGAATAAAATTCCAGTAAGGGGCGAAGTTGTAAAAGTGGAATTTTCGGCCCACAGTGATTATA
ATTCATTAATAAGATATATGAAGAAAATACCAAAACCTAAAAAAGTATTTGTAATGCATGGTGAAAGATATCAATCTTTA
TCATTTGCCATGACAATTTGGAAAAACTTTAAAATTCCAGCTATCGCTCCAACGGCGGGTAGTATATTACCTTTATTTTA
A

Upstream 100 bases:

>100_bases
GGCATCCATTATTACCCGGTGCGAAATGGGAAATATTGATAATTTTAATATTGAAATAAATAATAGAATATATAACGATA
ATAACCAATAAAGGGATATA

Downstream 100 bases:

>100_bases
ATAGTAGAAATATGACAAAAACAAAATACTACTTAAAATAAACAATAATTATAACAACTAACATAACAATAAATAATAAA
AAAGAGGAAAAATATGAATC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTIVRFHGGCHQIGMSCVEIDTKKSKILVDCGMNPSDNSLPKINPNDIDAVVVSHSHLDHCGAVPYFNFKNPIYSTIPSV
DLMYILWKDISKLSKTYPEENIQKAMNNIKAVNYREPKKITSDITMRLYDAGHILGSSSVYLDIGGKKLLYTGDINEIET
RTLKSADTDIDEIDTLIIESTYGAPTDIKPSRKALEKQLIDEISATIEKGGKVIIPVFAVGRSQEIIAVLHNYMRSKLLK
RVPIYVEGSLVHTTGIYMSHSEWLNPKIRNNLENRINPFGDVTIVNKENSSEIYNKEPCIIISTSGMVQGGPILQYLKLL
KSPKNKIILTGFQAEETLGRQLEDGAEEITPFRNKIPVRGEVVKVEFSAHSDYNSLIRYMKKIPKPKKVFVMHGERYQSL
SFAMTIWKNFKIPAIAPTAGSILPLF

Sequences:

>Translated_426_residues
MTIVRFHGGCHQIGMSCVEIDTKKSKILVDCGMNPSDNSLPKINPNDIDAVVVSHSHLDHCGAVPYFNFKNPIYSTIPSV
DLMYILWKDISKLSKTYPEENIQKAMNNIKAVNYREPKKITSDITMRLYDAGHILGSSSVYLDIGGKKLLYTGDINEIET
RTLKSADTDIDEIDTLIIESTYGAPTDIKPSRKALEKQLIDEISATIEKGGKVIIPVFAVGRSQEIIAVLHNYMRSKLLK
RVPIYVEGSLVHTTGIYMSHSEWLNPKIRNNLENRINPFGDVTIVNKENSSEIYNKEPCIIISTSGMVQGGPILQYLKLL
KSPKNKIILTGFQAEETLGRQLEDGAEEITPFRNKIPVRGEVVKVEFSAHSDYNSLIRYMKKIPKPKKVFVMHGERYQSL
SFAMTIWKNFKIPAIAPTAGSILPLF
>Mature_425_residues
TIVRFHGGCHQIGMSCVEIDTKKSKILVDCGMNPSDNSLPKINPNDIDAVVVSHSHLDHCGAVPYFNFKNPIYSTIPSVD
LMYILWKDISKLSKTYPEENIQKAMNNIKAVNYREPKKITSDITMRLYDAGHILGSSSVYLDIGGKKLLYTGDINEIETR
TLKSADTDIDEIDTLIIESTYGAPTDIKPSRKALEKQLIDEISATIEKGGKVIIPVFAVGRSQEIIAVLHNYMRSKLLKR
VPIYVEGSLVHTTGIYMSHSEWLNPKIRNNLENRINPFGDVTIVNKENSSEIYNKEPCIIISTSGMVQGGPILQYLKLLK
SPKNKIILTGFQAEETLGRQLEDGAEEITPFRNKIPVRGEVVKVEFSAHSDYNSLIRYMKKIPKPKKVFVMHGERYQSLS
FAMTIWKNFKIPAIAPTAGSILPLF

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI7706427, Length=429, Percent_Identity=31.7016317016317, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI33300633, Length=444, Percent_Identity=28.6036036036036, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI34101288, Length=388, Percent_Identity=24.2268041237113, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32566029, Length=426, Percent_Identity=29.1079812206573, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI32564696, Length=438, Percent_Identity=29.6803652968037, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17559452, Length=369, Percent_Identity=24.1192411924119, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323307, Length=422, Percent_Identity=27.2511848341232, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24648013, Length=427, Percent_Identity=30.6791569086651, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI21358523, Length=439, Percent_Identity=30.2961275626424, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI21358013, Length=369, Percent_Identity=23.5772357723577, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 47831; Mature: 47700

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVRFHGGCHQIGMSCVEIDTKKSKILVDCGMNPSDNSLPKINPNDIDAVVVSHSHLDH
CEEEEECCCHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCC
CGAVPYFNFKNPIYSTIPSVDLMYILWKDISKLSKTYPEENIQKAMNNIKAVNYREPKKI
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCHHH
TSDITMRLYDAGHILGSSSVYLDIGGKKLLYTGDINEIETRTLKSADTDIDEIDTLIIES
HHHHEEEEEECCCEECCCEEEEEECCCEEEEECCCCHHHHHHHHCCCCCHHHHHEEEEEC
TYGAPTDIKPSRKALEKQLIDEISATIEKGGKVIIPVFAVGRSQEIIAVLHNYMRSKLLK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
RVPIYVEGSLVHTTGIYMSHSEWLNPKIRNNLENRINPFGDVTIVNKENSSEIYNKEPCI
HCCEEEECCEEEEEEEEEECHHHCCCHHHHCHHHHCCCCCCEEEEECCCCCCCCCCCCEE
IISTSGMVQGGPILQYLKLLKSPKNKIILTGFQAEETLGRQLEDGAEEITPFRNKIPVRG
EEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCHHHHCCHHHCCCCCC
EVVKVEFSAHSDYNSLIRYMKKIPKPKKVFVMHGERYQSLSFAMTIWKNFKIPAIAPTAG
EEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCC
SILPLF
CCCCCC
>Mature Secondary Structure 
TIVRFHGGCHQIGMSCVEIDTKKSKILVDCGMNPSDNSLPKINPNDIDAVVVSHSHLDH
EEEEECCCHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCC
CGAVPYFNFKNPIYSTIPSVDLMYILWKDISKLSKTYPEENIQKAMNNIKAVNYREPKKI
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCHHH
TSDITMRLYDAGHILGSSSVYLDIGGKKLLYTGDINEIETRTLKSADTDIDEIDTLIIES
HHHHEEEEEECCCEECCCEEEEEECCCEEEEECCCCHHHHHHHHCCCCCHHHHHEEEEEC
TYGAPTDIKPSRKALEKQLIDEISATIEKGGKVIIPVFAVGRSQEIIAVLHNYMRSKLLK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
RVPIYVEGSLVHTTGIYMSHSEWLNPKIRNNLENRINPFGDVTIVNKENSSEIYNKEPCI
HCCEEEECCEEEEEEEEEECHHHCCCHHHHCHHHHCCCCCCEEEEECCCCCCCCCCCCEE
IISTSGMVQGGPILQYLKLLKSPKNKIILTGFQAEETLGRQLEDGAEEITPFRNKIPVRG
EEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCHHHHCCHHHCCCCCC
EVVKVEFSAHSDYNSLIRYMKKIPKPKKVFVMHGERYQSLSFAMTIWKNFKIPAIAPTAG
EEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCC
SILPLF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]