BacMap

Definition	Methanococcus aeolicus Nankai-3, complete genome.
Accession	NC_009635
Length	1,569,500

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The map label for this gene is gabD [C]

Identifier: 150401454

GI number: 150401454

Start: 1058606

End: 1060003

Strand: Reverse

Name: gabD [C]

Synonym: Maeo_1030

Alternate gene names: 150401454

Gene position: 1060003-1058606 (Counterclockwise)

Preceding gene: 150401456

Following gene: 150401453

Centisome position: 67.54

GC content: 30.33

Gene sequence:

>1398_bases
ATGTTTATAAATGGAGAATGGATAAATAGAAAAGATATAGAAGTAAAAAATCCATACAATAATGAAATAATAGGGTATAT
ACCATCATTAAGTAGAAATGAGACAAAAGAAGCAATAAAAATAGCCGAGGAACATAAATCTACAATGAAAAATCTAAGCC
CAACTATAAGATATAATATATTAATGAAAATAGCTTCAGAATTATCCAAAAATAAAAGAGAATTGGCAAAATTAATAACT
ATTGATGTAGGAAAGCCAATAAAACAGTCAATTATTGAGGTAGATAGAACAATAACCACATTTAAATTTTCAGCATTTTA
TTCAAGGGAGTTAAGGGGGGAAACTATACCTTTTGACGATGGGATGGTAATAACAAAAAGAGAACCAGTTGGATTAGTTG
GTGCAATTACTCCATTTAATTTTCCATTAAACCTATTTGCACATAAAATAGCTCCGGCAATAGCTATGGGAAATAGTATA
GTAGCTCACCCATCATCAAAAGCTCCGATGATAACTATTGAATTAACAAAGATTATTGAAAAAGTTTTAAAAAGTAAAAA
AATACCGTTGGGAGTATTTAACCTATTAACTGGGGAGGGGCATATTGTAGGGGATGAAATCGTAAAAAATAATAAAATAA
ATAAACTGTCATTTACTGGAAGTGTAGAAGTTGGCGAATCAATTACAAAAAAGGCAGGATTTAAAAAAATAACTCTTGAA
TTGGGGGGAAATAATCCAATGATAATATTAAAAGATGCAAATATAAATAAAGCCGTGGAATCTTGTATGAGCGGTAAATT
TTTAAATTCTGGTCAGGTTTGTATTTCTGTTGGACGGGTTCTAATAGAGCAGGAAGTGGCAGATGAATTTATAAATAAAA
TAGTTGAAAAAGTTAAAAAATTAAAAATAGGCAATCCATTAGATGAGGATACAAATATTAGTTCTTTAATATCATTGGAT
AGTGCGGAAAGAGTGGAAAAATTAATAAATAAATCAATAGGGCAAGGGGGAAAATTGATATGCGGTGGAAAGAGGGAAAA
TAGTATAATATATCCAACAATATTGGAAATCACAGCGGATAATATTTTAGCAAATATCGAAATTTTTGCCCCAGTTTTAC
CAATTATTAGGGTAAATGACATGAATGAGGCACTAAATCAGGCAAATAATTCAAATTATGGGCTCCACTCGGGAGTATTT
ACACAGGACATAAATAAAGCATTATATTTTGCAGACAATTTGGAATATGGGGGAGTATTGATAAACAATAGTCCTACATT
TAGAATAGACAACATGCCATTTGGAGGAATTAAACACAGTGGATTAGGTAGGGAAGGTATAAAATATGCCATTGACGAAA
TGAGCGAAATTAAAACTATTATAGTTAATACTAAATAA

Upstream 100 bases:

>100_bases
TTTGTCATTATAATTATTATCCTTAATAATATTACCAAATTATTTAAATTTATATTTTATATGTTCAAAAAGTTCCAAGA
TACAAAAAGGGGTGATATAT

Downstream 100 bases:

>100_bases
AATAATATTAATAAATAATAAAATAAGGAAAATTATGCAGATAAATAATAAATCCAACAATAAATTTAAAATAATACACT
TAAAAACTACAATTTCCACA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MFINGEWINRKDIEVKNPYNNEIIGYIPSLSRNETKEAIKIAEEHKSTMKNLSPTIRYNILMKIASELSKNKRELAKLIT
IDVGKPIKQSIIEVDRTITTFKFSAFYSRELRGETIPFDDGMVITKREPVGLVGAITPFNFPLNLFAHKIAPAIAMGNSI
VAHPSSKAPMITIELTKIIEKVLKSKKIPLGVFNLLTGEGHIVGDEIVKNNKINKLSFTGSVEVGESITKKAGFKKITLE
LGGNNPMIILKDANINKAVESCMSGKFLNSGQVCISVGRVLIEQEVADEFINKIVEKVKKLKIGNPLDEDTNISSLISLD
SAERVEKLINKSIGQGGKLICGGKRENSIIYPTILEITADNILANIEIFAPVLPIIRVNDMNEALNQANNSNYGLHSGVF
TQDINKALYFADNLEYGGVLINNSPTFRIDNMPFGGIKHSGLGREGIKYAIDEMSEIKTIIVNTK

Sequences:

>Translated_465_residues
MFINGEWINRKDIEVKNPYNNEIIGYIPSLSRNETKEAIKIAEEHKSTMKNLSPTIRYNILMKIASELSKNKRELAKLIT
IDVGKPIKQSIIEVDRTITTFKFSAFYSRELRGETIPFDDGMVITKREPVGLVGAITPFNFPLNLFAHKIAPAIAMGNSI
VAHPSSKAPMITIELTKIIEKVLKSKKIPLGVFNLLTGEGHIVGDEIVKNNKINKLSFTGSVEVGESITKKAGFKKITLE
LGGNNPMIILKDANINKAVESCMSGKFLNSGQVCISVGRVLIEQEVADEFINKIVEKVKKLKIGNPLDEDTNISSLISLD
SAERVEKLINKSIGQGGKLICGGKRENSIIYPTILEITADNILANIEIFAPVLPIIRVNDMNEALNQANNSNYGLHSGVF
TQDINKALYFADNLEYGGVLINNSPTFRIDNMPFGGIKHSGLGREGIKYAIDEMSEIKTIIVNTK
>Mature_465_residues
MFINGEWINRKDIEVKNPYNNEIIGYIPSLSRNETKEAIKIAEEHKSTMKNLSPTIRYNILMKIASELSKNKRELAKLIT
IDVGKPIKQSIIEVDRTITTFKFSAFYSRELRGETIPFDDGMVITKREPVGLVGAITPFNFPLNLFAHKIAPAIAMGNSI
VAHPSSKAPMITIELTKIIEKVLKSKKIPLGVFNLLTGEGHIVGDEIVKNNKINKLSFTGSVEVGESITKKAGFKKITLE
LGGNNPMIILKDANINKAVESCMSGKFLNSGQVCISVGRVLIEQEVADEFINKIVEKVKKLKIGNPLDEDTNISSLISLD
SAERVEKLINKSIGQGGKLICGGKRENSIIYPTILEITADNILANIEIFAPVLPIIRVNDMNEALNQANNSNYGLHSGVF
TQDINKALYFADNLEYGGVLINNSPTFRIDNMPFGGIKHSGLGREGIKYAIDEMSEIKTIIVNTK

Specific function: Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family

Homologues:

Organism=Homo sapiens, GI25777730, Length=479, Percent_Identity=36.1169102296451, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI153266822, Length=477, Percent_Identity=36.4779874213836, Blast_Score=308, Evalue=6e-84,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=36.0587002096436, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI25777728, Length=415, Percent_Identity=38.3132530120482, Blast_Score=291, Evalue=7e-79,
Organism=Homo sapiens, GI25777732, Length=477, Percent_Identity=33.5429769392034, Blast_Score=289, Evalue=4e-78,
Organism=Homo sapiens, GI21361176, Length=477, Percent_Identity=33.3333333333333, Blast_Score=282, Evalue=5e-76,
Organism=Homo sapiens, GI21614513, Length=480, Percent_Identity=33.5416666666667, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI12007648, Length=478, Percent_Identity=31.7991631799163, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI25777726, Length=477, Percent_Identity=32.7044025157233, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI238814322, Length=481, Percent_Identity=31.8087318087318, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=33.630289532294, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI4507229, Length=473, Percent_Identity=30.8668076109937, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI25777721, Length=482, Percent_Identity=30.2904564315353, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI25952152, Length=468, Percent_Identity=30.5555555555556, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI188035924, Length=471, Percent_Identity=28.8747346072187, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI310128093, Length=453, Percent_Identity=29.5805739514349, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI310128103, Length=453, Percent_Identity=29.3598233995585, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI310128091, Length=453, Percent_Identity=28.6975717439294, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI301500698, Length=475, Percent_Identity=26.5263157894737, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI11095441, Length=486, Percent_Identity=25.9259259259259, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI310128089, Length=284, Percent_Identity=30.6338028169014, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI310128087, Length=286, Percent_Identity=30.4195804195804, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI73466520, Length=343, Percent_Identity=27.9883381924198, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4557303, Length=343, Percent_Identity=27.9883381924198, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI310128095, Length=298, Percent_Identity=29.1946308724832, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI238859541, Length=415, Percent_Identity=27.710843373494, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI25777736, Length=415, Percent_Identity=27.710843373494, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI25777734, Length=415, Percent_Identity=27.710843373494, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI206597441, Length=345, Percent_Identity=30.1449275362319, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI206597439, Length=345, Percent_Identity=30.1449275362319, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI22907049, Length=345, Percent_Identity=30.1449275362319, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI73695881, Length=352, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI73695879, Length=352, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI71773324, Length=348, Percent_Identity=25.5747126436782, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4502043, Length=348, Percent_Identity=25.5747126436782, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI238814371, Length=348, Percent_Identity=25.5747126436782, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI223972651, Length=458, Percent_Identity=23.1441048034935, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310128097, Length=247, Percent_Identity=29.5546558704453, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310128099, Length=228, Percent_Identity=30.7017543859649, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310128101, Length=228, Percent_Identity=30.7017543859649, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI223972653, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789015, Length=474, Percent_Identity=35.4430379746835, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI87081896, Length=424, Percent_Identity=35.377358490566, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787558, Length=479, Percent_Identity=32.776617954071, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1787684, Length=477, Percent_Identity=31.4465408805031, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1786504, Length=481, Percent_Identity=30.3534303534304, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787715, Length=476, Percent_Identity=30.8823529411765, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082295, Length=483, Percent_Identity=31.4699792960663, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87081926, Length=451, Percent_Identity=30.5986696230599, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788042, Length=466, Percent_Identity=28.5407725321888, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1787250, Length=443, Percent_Identity=27.9909706546275, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787653, Length=411, Percent_Identity=19.9513381995134, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788797, Length=408, Percent_Identity=20.5882352941176, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562198, Length=477, Percent_Identity=35.8490566037736, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI25144435, Length=477, Percent_Identity=33.5429769392034, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI133930964, Length=484, Percent_Identity=32.6446280991736, Blast_Score=268, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI32564736, Length=420, Percent_Identity=35, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI25143876, Length=482, Percent_Identity=32.7800829875519, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI25143874, Length=482, Percent_Identity=32.7800829875519, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17534119, Length=470, Percent_Identity=32.7659574468085, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI71995606, Length=484, Percent_Identity=31.198347107438, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17551164, Length=485, Percent_Identity=31.5463917525773, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI71995613, Length=420, Percent_Identity=30.952380952381, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI115534176, Length=474, Percent_Identity=27.8481012658228, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71986308, Length=470, Percent_Identity=27.8723404255319, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI25146391, Length=343, Percent_Identity=29.1545189504373, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI32566756, Length=343, Percent_Identity=29.1545189504373, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25146394, Length=343, Percent_Identity=29.1545189504373, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17564084, Length=354, Percent_Identity=28.2485875706215, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17534447, Length=437, Percent_Identity=27.4599542334096, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115532534, Length=386, Percent_Identity=28.4974093264249, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564151, Length=395, Percent_Identity=27.0886075949367, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990744, Length=288, Percent_Identity=27.0833333333333, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324950, Length=474, Percent_Identity=35.2320675105485, Blast_Score=269, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6319478, Length=474, Percent_Identity=32.4894514767932, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6320917, Length=473, Percent_Identity=31.2896405919662, Blast_Score=255, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6325196, Length=474, Percent_Identity=31.0126582278481, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323821, Length=490, Percent_Identity=31.4285714285714, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6323822, Length=487, Percent_Identity=30.3901437371663, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321828, Length=480, Percent_Identity=24.375, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321826, Length=483, Percent_Identity=24.8447204968944, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=373, Percent_Identity=29.4906166219839, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129399, Length=480, Percent_Identity=34.1666666666667, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24650465, Length=475, Percent_Identity=34.9473684210526, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24585660, Length=482, Percent_Identity=31.3278008298755, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI281362580, Length=477, Percent_Identity=31.8658280922432, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI62472918, Length=477, Percent_Identity=31.8658280922432, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI62472926, Length=477, Percent_Identity=31.8658280922432, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI62472936, Length=477, Percent_Identity=31.8658280922432, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI21356737, Length=477, Percent_Identity=31.8658280922432, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24666674, Length=473, Percent_Identity=29.1754756871036, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24638876, Length=470, Percent_Identity=26.5957446808511, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24638878, Length=470, Percent_Identity=26.5957446808511, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281360299, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360297, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360295, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24586250, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360301, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360303, Length=439, Percent_Identity=26.1958997722096, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45552499, Length=439, Percent_Identity=26.1958997722096, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24668425, Length=434, Percent_Identity=26.9585253456221, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668417, Length=434, Percent_Identity=26.9585253456221, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668413, Length=434, Percent_Identity=26.9585253456221, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574525, Length=442, Percent_Identity=21.7194570135747, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571806, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571798, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571796, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571794, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571802, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571800, Length=468, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360293, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LADH_META3 (A6UVT6)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325220.1
- ProteinModelPortal:   A6UVT6
- SMR:   A6UVT6
- STRING:   A6UVT6
- GeneID:   5327289
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1030
- eggNOG:   arNOG04288
- HOGENOM:   HBG752218
- OMA:   ITKKAGF
- ProtClustDB:   CLSK876565
- BioCyc:   MAEO419665:MAEO_1030-MONOMER
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.22

Molecular weight: Translated: 51327; Mature: 51327

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU; PS00012 PHOSPHOPANTETHEINE

Important sites: ACT_SITE 240-240 ACT_SITE 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFINGEWINRKDIEVKNPYNNEIIGYIPSLSRNETKEAIKIAEEHKSTMKNLSPTIRYNI
CEECCCCCCCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LMKIASELSKNKRELAKLITIDVGKPIKQSIIEVDRTITTFKFSAFYSRELRGETIPFDD
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHEEEEEHHHHHHHHCCCCCCCCC
GMVITKREPVGLVGAITPFNFPLNLFAHKIAPAIAMGNSIVAHPSSKAPMITIELTKIIE
CEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEHHHHHH
KVLKSKKIPLGVFNLLTGEGHIVGDEIVKNNKINKLSFTGSVEVGESITKKAGFKKITLE
HHHHHCCCCEEEHEEECCCCCEECHHHHCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEE
LGGNNPMIILKDANINKAVESCMSGKFLNSGQVCISVGRVLIEQEVADEFINKIVEKVKK
ECCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIGNPLDEDTNISSLISLDSAERVEKLINKSIGQGGKLICGGKRENSIIYPTILEITAD
HCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEEEECC
NILANIEIFAPVLPIIRVNDMNEALNQANNSNYGLHSGVFTQDINKALYFADNLEYGGVL
HHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEE
INNSPTFRIDNMPFGGIKHSGLGREGIKYAIDEMSEIKTIIVNTK
ECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MFINGEWINRKDIEVKNPYNNEIIGYIPSLSRNETKEAIKIAEEHKSTMKNLSPTIRYNI
CEECCCCCCCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LMKIASELSKNKRELAKLITIDVGKPIKQSIIEVDRTITTFKFSAFYSRELRGETIPFDD
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHEEEEEHHHHHHHHCCCCCCCCC
GMVITKREPVGLVGAITPFNFPLNLFAHKIAPAIAMGNSIVAHPSSKAPMITIELTKIIE
CEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEHHHHHH
KVLKSKKIPLGVFNLLTGEGHIVGDEIVKNNKINKLSFTGSVEVGESITKKAGFKKITLE
HHHHHCCCCEEEHEEECCCCCEECHHHHCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEE
LGGNNPMIILKDANINKAVESCMSGKFLNSGQVCISVGRVLIEQEVADEFINKIVEKVKK
ECCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIGNPLDEDTNISSLISLDSAERVEKLINKSIGQGGKLICGGKRENSIIYPTILEITAD
HCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEEEECC
NILANIEIFAPVLPIIRVNDMNEALNQANNSNYGLHSGVFTQDINKALYFADNLEYGGVL
HHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEE
INNSPTFRIDNMPFGGIKHSGLGREGIKYAIDEMSEIKTIIVNTK
ECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA