| Definition | Methanococcus aeolicus Nankai-3, complete genome. |
|---|---|
| Accession | NC_009635 |
| Length | 1,569,500 |
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The map label for this gene is hmd [H]
Identifier: 150401449
GI number: 150401449
Start: 1053386
End: 1054414
Strand: Direct
Name: hmd [H]
Synonym: Maeo_1025
Alternate gene names: 150401449
Gene position: 1053386-1054414 (Clockwise)
Preceding gene: 150401447
Following gene: 150401450
Centisome position: 67.12
GC content: 36.25
Gene sequence:
>1029_bases TTGAAAGTAGCAATATTAGGAGCAGGATGTTATAGGTCCCATGCAGCATGTGGTATTACAAACTTTTCAAGAGCAGCAGA AGTTGCAAATAAAGTAGGAATTCCGGAAATAACAATGACTCATTCAACTATCACGATGGGGGCAGAATTATTACATTTAG TAGATGAAATTGATGAAGTTGTTGTTTCAGACCCATGCTTTGCAGAAGAACCGGGTTTAATTATAATTGACGAATTTGAC TGTAAAGAAGTAATGGAAGCTCATTTAGCAGGAAAAGCAGAGGATGTAATGCCAGCTATTAGGGATGCTGTTAAAGCTAA GGCAAAAGATTCGCCAAAACCACCAAAAGGATGTATCCACTTTGTTAATCCAGAAAAAGTTGGATTAAAAGTTACATCAG ACGACAGAGAAGCTATTGAAGGAGCCGATATAGTAATTACATGGTTACCAAAAGGAGGAAGCCAGCCAGCAATTATTGAA AAATTCGTAGATGCAATAAAAGAAGGAGCTATTGTAACACATGCATGCACCATTCCAACACCAAAATTCGCAAAAATCTT TAAAGATTTAGGAAGAGAAGATTTAAACATTGTATCATTCCATCCAGGATGTGTTCCTGAAATGAAAGGACAAGTATATT TATCAGAAGGATATGCTAGTGAAGAAGCTGTTGAGAAATTATACAAAATCGCAAAAATATCAAGAGGAACAGCATTTAAA ATGCCAGCTAACTTAATTAGTCCTGTATGTGATATGGGTTCAGCTGTTACAGCACCAGTTTATGCTGCAATATTATCATA CAGAGATGCAGTTACAAACATTTTAGGAGCTCCTGCTGATTTCGCTCAAATGATGGCAGACGAAGCTATTACTCAAATGT TAGAATTAATGAGAAATGAAGGAATACAAAATATGGAAAACAAATTAAACCCAGGAGCATTAACCGGAACAGCAGACAGT ATGTGCTTTGGTCCATTGTCAGAATTACTTCCAGCTTCATTGAAAGTTCTCGAAGAACACAAAAAATAA
Upstream 100 bases:
>100_bases GTATTAATAATTTTTATAGGTATTGCATTAAATGAAATTAAATCGTTAAGTTTTTATATAATATTTATACAAATTAGTAT TATAAAAATGAGGTGATATT
Downstream 100 bases:
>100_bases TTAATAAATATTTATAATCCCATATTTTCTTTTTTTTAACATTTTTATGTCATAAGAATAATTTATTTTTAAATTAAATA TATTAAATTTATAAACCTCC
Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase
Products: NA
Alternate protein names: H(2)-dependent methylene-H(4)MPT dehydrogenase; H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase; N(5),N(10)-methenyltetrahydromethanopterin hydrogenase [H]
Number of amino acids: Translated: 342; Mature: 342
Protein sequence:
>342_residues MKVAILGAGCYRSHAACGITNFSRAAEVANKVGIPEITMTHSTITMGAELLHLVDEIDEVVVSDPCFAEEPGLIIIDEFD CKEVMEAHLAGKAEDVMPAIRDAVKAKAKDSPKPPKGCIHFVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIE KFVDAIKEGAIVTHACTIPTPKFAKIFKDLGREDLNIVSFHPGCVPEMKGQVYLSEGYASEEAVEKLYKIAKISRGTAFK MPANLISPVCDMGSAVTAPVYAAILSYRDAVTNILGAPADFAQMMADEAITQMLELMRNEGIQNMENKLNPGALTGTADS MCFGPLSELLPASLKVLEEHKK
Sequences:
>Translated_342_residues MKVAILGAGCYRSHAACGITNFSRAAEVANKVGIPEITMTHSTITMGAELLHLVDEIDEVVVSDPCFAEEPGLIIIDEFD CKEVMEAHLAGKAEDVMPAIRDAVKAKAKDSPKPPKGCIHFVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIE KFVDAIKEGAIVTHACTIPTPKFAKIFKDLGREDLNIVSFHPGCVPEMKGQVYLSEGYASEEAVEKLYKIAKISRGTAFK MPANLISPVCDMGSAVTAPVYAAILSYRDAVTNILGAPADFAQMMADEAITQMLELMRNEGIQNMENKLNPGALTGTADS MCFGPLSELLPASLKVLEEHKK >Mature_342_residues MKVAILGAGCYRSHAACGITNFSRAAEVANKVGIPEITMTHSTITMGAELLHLVDEIDEVVVSDPCFAEEPGLIIIDEFD CKEVMEAHLAGKAEDVMPAIRDAVKAKAKDSPKPPKGCIHFVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIE KFVDAIKEGAIVTHACTIPTPKFAKIFKDLGREDLNIVSFHPGCVPEMKGQVYLSEGYASEEAVEKLYKIAKISRGTAFK MPANLISPVCDMGSAVTAPVYAAILSYRDAVTNILGAPADFAQMMADEAITQMLELMRNEGIQNMENKLNPGALTGTADS MCFGPLSELLPASLKVLEEHKK
Specific function: Catalyzes the reversible reduction of methenyl- H(4)MPT(+) to methylene-H(4)MPT [H]
COG id: COG4074
COG function: function code C; H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the HMD family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008927 - InterPro: IPR004889 - InterPro: IPR010062 - InterPro: IPR016040 [H]
Pfam domain/function: PF03201 HMD [H]
EC number: =1.12.98.2 [H]
Molecular weight: Translated: 36743; Mature: 36743
Theoretical pI: Translated: 4.86; Mature: 4.86
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 6.7 %Cys+Met (Translated Protein) 2.6 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 6.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVAILGAGCYRSHAACGITNFSRAAEVANKVGIPEITMTHSTITMGAELLHLVDEIDEV CEEEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHH VVSDPCFAEEPGLIIIDEFDCKEVMEAHLAGKAEDVMPAIRDAVKAKAKDSPKPPKGCIH HHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEE FVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIEKFVDAIKEGAIVTHACTIPT ECCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCC PKFAKIFKDLGREDLNIVSFHPGCVPEMKGQVYLSEGYASEEAVEKLYKIAKISRGTAFK HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEE MPANLISPVCDMGSAVTAPVYAAILSYRDAVTNILGAPADFAQMMADEAITQMLELMRNE CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC GIQNMENKLNPGALTGTADSMCFGPLSELLPASLKVLEEHKK CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MKVAILGAGCYRSHAACGITNFSRAAEVANKVGIPEITMTHSTITMGAELLHLVDEIDEV CEEEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHH VVSDPCFAEEPGLIIIDEFDCKEVMEAHLAGKAEDVMPAIRDAVKAKAKDSPKPPKGCIH HHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEE FVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIEKFVDAIKEGAIVTHACTIPT ECCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCC PKFAKIFKDLGREDLNIVSFHPGCVPEMKGQVYLSEGYASEEAVEKLYKIAKISRGTAFK HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEE MPANLISPVCDMGSAVTAPVYAAILSYRDAVTNILGAPADFAQMMADEAITQMLELMRNE CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC GIQNMENKLNPGALTGTADSMCFGPLSELLPASLKVLEEHKK CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8599536 [H]