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The map label for this gene is infB

Identifier: 150401328

GI number: 150401328

Start: 927776

End: 929572

Strand: Reverse

Name: infB

Synonym: Maeo_0901

Alternate gene names: 150401328

Gene position: 929572-927776 (Counterclockwise)

Preceding gene: 150401329

Following gene: 150401327

Centisome position: 59.23

GC content: 35.95

Gene sequence:

>1797_bases
ATGGCATTAAGATGTCCAATAGTTAGTGTTCTTGGTCATGTAGATCATGGAAAAACAAGTTTGCTCGATAAAATTAGAAA
AACGAGGGTTACACAGAGAGAGGCAGGGGGAATTACTCAACACATCGGGGCAAGTGAAATTCCAATAGATATTATAAAGA
AAATATCAAAGGATTTAATTAAAATGTTGGGTGCAAATTTAACCATTCCCGGAATATTAGTTATAGATACACCGGGGCAT
GCAGCATTTACTTCACTCAGAAAAAGAGGGGGAGCTCTGGCAGATATTGCAGTATTGATTGTAGATATAAATGAAGGATT
CATGCCCCAAACAATAGAGGCACTAAATATATTAAAACAAAATAAAACTCCATTTGTAGTTGCAGCAAATAAAATTGATA
GGTTGCCGGGGTGGAGCTCCGTAGATGGGGCATTCATTACAAACTTTAACGAACAGAAACAGCACCCAAATGCTTTAACA
GAATTTGAAATTAAGTTGTATGAAAATGTGATAGCACCTCTGGCAGAAAGGGGATTTGAAGCCGACCTTTTTTCCAGAGT
AAAAGATGTTTCAAAAACCATAAATATTGTGCCAATATCTGCAATGACGGGGGAGGGAATCCCTGATTTACTTGTTATGA
TTTCCGGTCTTGCTCAAAGATTTATGGAACAAAATTTAAAATTAAATGTAGAAGGATATGCCAAAGGAACAGTTCTTGAA
GTTAAAGAAGAAAGAGGGCTTGGAAAAACCATGGATGCCATAATTTATGATGGCGTGGCAAAAAGGGGGGACTACATTGT
AATAGGAAATCCCGACGGAATTGTGGTTTCTAGAATAAAGGCTCTTTTAAAGCCAAAGGCACTAGATGAAATGAGGGACC
CGAGGGATAAATTTAAAACAATGAATGAAATTAGTGCTGCAACTGGTCTTAAAATATCTGCCCCTGATTTAGACAATATT
ATAGCAGGTAGCCCTTTAAGAATTGTGCCAAAAAATATGGTGGAACAGGCAAAAGCCGAAATTGTGGAAGAGATAGAGGA
AACAGCCATACAACTAGACGAAGAAGGTATAATTATAAAGGCAGATACTCTTGGTTCATTGGAGGCACTTGCAACAGAAT
TAAGAAAGGTAGGTGCAAAAATCAAAAAGGCAGAAGTTGGAGATGTTTCAAAAAAAGATGTAATCGAAGCTTCATCTTAT
GCTCAAACTAATCCATTAAATGGGGCAATTATATTATTTAACTCAAAACTATTGGCAGATGCAAAAAGTGAAGTAGAAAA
ATATGAGATAAAAACATTCGAAGGAGACATTATTTATAAACTTGTTGAAGATTATGAAGAATGGACAAAAGAAATGAAAG
AATTATTAAAATCAGATGAGTTTAATAGATTAACAAAACCCGCCATATTGAGAATAATTCCCGGATGTATTTTTAATAAA
ACAAAACCCGCCATTTGTGGCGTGGAGGTAGTATATGGAACGCTGAGAGTTGGCTGTTCTGTTGTAGATGAACAGGGTAA
AAGATTAGGGACTGTTAAAGAAATTAAAGATAAAAAACAGGAAAATATAAAAGAGGCAAAAGTTGGAATGGAGGTTCCAA
TTTCTATTGATGGAACTGTAATTCTTGGGAGACATATCGGGGAAGATGATATTATGTATGTGGAGCTCCCTGAACCAGAG
GTAAGAATATTATCTCATAATTATATGGGCGAGTTAAGGGGGGACGAAAGAGAGGCATTTGAAAGATATGTGGAATTAAA
AAGAAAGTTAGAGAACAATCCATTCTGGGGAATTTAA

Upstream 100 bases:

>100_bases
ATATTATTAGATAACAACATATTATTTTATTTTTATTTTTAACGGTTATTATGTGATTATAGTGATATTATTTTATTTTT
ATTTTTAAACGGTGATAGAT

Downstream 100 bases:

>100_bases
TTAATTTTTAATTCAATTTCCTTATATTTATATTTCAAATATGATGTCAATATTAATAATATACATATATGTTAATAATA
TATATGTTCAAGAACTTATT

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MALRCPIVSVLGHVDHGKTSLLDKIRKTRVTQREAGGITQHIGASEIPIDIIKKISKDLIKMLGANLTIPGILVIDTPGH
AAFTSLRKRGGALADIAVLIVDINEGFMPQTIEALNILKQNKTPFVVAANKIDRLPGWSSVDGAFITNFNEQKQHPNALT
EFEIKLYENVIAPLAERGFEADLFSRVKDVSKTINIVPISAMTGEGIPDLLVMISGLAQRFMEQNLKLNVEGYAKGTVLE
VKEERGLGKTMDAIIYDGVAKRGDYIVIGNPDGIVVSRIKALLKPKALDEMRDPRDKFKTMNEISAATGLKISAPDLDNI
IAGSPLRIVPKNMVEQAKAEIVEEIEETAIQLDEEGIIIKADTLGSLEALATELRKVGAKIKKAEVGDVSKKDVIEASSY
AQTNPLNGAIILFNSKLLADAKSEVEKYEIKTFEGDIIYKLVEDYEEWTKEMKELLKSDEFNRLTKPAILRIIPGCIFNK
TKPAICGVEVVYGTLRVGCSVVDEQGKRLGTVKEIKDKKQENIKEAKVGMEVPISIDGTVILGRHIGEDDIMYVELPEPE
VRILSHNYMGELRGDEREAFERYVELKRKLENNPFWGI

Sequences:

>Translated_598_residues
MALRCPIVSVLGHVDHGKTSLLDKIRKTRVTQREAGGITQHIGASEIPIDIIKKISKDLIKMLGANLTIPGILVIDTPGH
AAFTSLRKRGGALADIAVLIVDINEGFMPQTIEALNILKQNKTPFVVAANKIDRLPGWSSVDGAFITNFNEQKQHPNALT
EFEIKLYENVIAPLAERGFEADLFSRVKDVSKTINIVPISAMTGEGIPDLLVMISGLAQRFMEQNLKLNVEGYAKGTVLE
VKEERGLGKTMDAIIYDGVAKRGDYIVIGNPDGIVVSRIKALLKPKALDEMRDPRDKFKTMNEISAATGLKISAPDLDNI
IAGSPLRIVPKNMVEQAKAEIVEEIEETAIQLDEEGIIIKADTLGSLEALATELRKVGAKIKKAEVGDVSKKDVIEASSY
AQTNPLNGAIILFNSKLLADAKSEVEKYEIKTFEGDIIYKLVEDYEEWTKEMKELLKSDEFNRLTKPAILRIIPGCIFNK
TKPAICGVEVVYGTLRVGCSVVDEQGKRLGTVKEIKDKKQENIKEAKVGMEVPISIDGTVILGRHIGEDDIMYVELPEPE
VRILSHNYMGELRGDEREAFERYVELKRKLENNPFWGI
>Mature_597_residues
ALRCPIVSVLGHVDHGKTSLLDKIRKTRVTQREAGGITQHIGASEIPIDIIKKISKDLIKMLGANLTIPGILVIDTPGHA
AFTSLRKRGGALADIAVLIVDINEGFMPQTIEALNILKQNKTPFVVAANKIDRLPGWSSVDGAFITNFNEQKQHPNALTE
FEIKLYENVIAPLAERGFEADLFSRVKDVSKTINIVPISAMTGEGIPDLLVMISGLAQRFMEQNLKLNVEGYAKGTVLEV
KEERGLGKTMDAIIYDGVAKRGDYIVIGNPDGIVVSRIKALLKPKALDEMRDPRDKFKTMNEISAATGLKISAPDLDNII
AGSPLRIVPKNMVEQAKAEIVEEIEETAIQLDEEGIIIKADTLGSLEALATELRKVGAKIKKAEVGDVSKKDVIEASSYA
QTNPLNGAIILFNSKLLADAKSEVEKYEIKTFEGDIIYKLVEDYEEWTKEMKELLKSDEFNRLTKPAILRIIPGCIFNKT
KPAICGVEVVYGTLRVGCSVVDEQGKRLGTVKEIKDKKQENIKEAKVGMEVPISIDGTVILGRHIGEDDIMYVELPEPEV
RILSHNYMGELRGDEREAFERYVELKRKLENNPFWGI

Specific function: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family

Homologues:

Organism=Homo sapiens, GI84043963, Length=602, Percent_Identity=36.3787375415282, Blast_Score=342, Evalue=7e-94,
Organism=Homo sapiens, GI53729339, Length=266, Percent_Identity=33.0827067669173, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI53729337, Length=266, Percent_Identity=33.0827067669173, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI1789559, Length=579, Percent_Identity=28.6701208981002, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI212656558, Length=600, Percent_Identity=34.6666666666667, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI71994658, Length=269, Percent_Identity=29.368029739777, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319282, Length=570, Percent_Identity=37.3684210526316, Blast_Score=342, Evalue=9e-95,
Organism=Saccharomyces cerevisiae, GI6324550, Length=518, Percent_Identity=28.957528957529, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656849, Length=561, Percent_Identity=38.1461675579323, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI28572034, Length=266, Percent_Identity=31.203007518797, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI160714833, Length=87, Percent_Identity=44.8275862068966, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): IF2P_META3 (A6UVG0)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325094.1
- ProteinModelPortal:   A6UVG0
- SMR:   A6UVG0
- STRING:   A6UVG0
- GeneID:   5327717
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0901
- eggNOG:   arNOG04413
- HOGENOM:   HBG635083
- OMA:   SPLRIVP
- ProtClustDB:   PRK04004
- BioCyc:   MAEO419665:MAEO_0901-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00100_A
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR004544
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000
- Gene3D:   G3DSA:3.40.50.10050
- PANTHER:   PTHR23115:SF41
- PRINTS:   PR00315
- TIGRFAMs:   TIGR00491
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; SSF52156 TIF_IF2_dom3; SSF50447 Translat_factor

EC number: NA

Molecular weight: Translated: 66117; Mature: 65985

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01176 IF2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRCPIVSVLGHVDHGKTSLLDKIRKTRVTQREAGGITQHIGASEIPIDIIKKISKDLI
CCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
KMLGANLTIPGILVIDTPGHAAFTSLRKRGGALADIAVLIVDINEGFMPQTIEALNILKQ
HHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHC
NKTPFVVAANKIDRLPGWSSVDGAFITNFNEQKQHPNALTEFEIKLYENVIAPLAERGFE
CCCCEEEECCHHHCCCCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
ADLFSRVKDVSKTINIVPISAMTGEGIPDLLVMISGLAQRFMEQNLKLNVEGYAKGTVLE
HHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
VKEERGLGKTMDAIIYDGVAKRGDYIVIGNPDGIVVSRIKALLKPKALDEMRDPRDKFKT
EHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCHHHHHHH
MNEISAATGLKISAPDLDNIIAGSPLRIVPKNMVEQAKAEIVEEIEETAIQLDEEGIIIK
HHHHHHHCCCEEECCCCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEEE
ADTLGSLEALATELRKVGAKIKKAEVGDVSKKDVIEASSYAQTNPLNGAIILFNSKLLAD
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCHHHHH
AKSEVEKYEIKTFEGDIIYKLVEDYEEWTKEMKELLKSDEFNRLTKPAILRIIPGCIFNK
HHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHCCC
TKPAICGVEVVYGTLRVGCSVVDEQGKRLGTVKEIKDKKQENIKEAKVGMEVPISIDGTV
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCEE
ILGRHIGEDDIMYVELPEPEVRILSHNYMGELRGDEREAFERYVELKRKLENNPFWGI
EEECCCCCCCEEEEECCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ALRCPIVSVLGHVDHGKTSLLDKIRKTRVTQREAGGITQHIGASEIPIDIIKKISKDLI
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
KMLGANLTIPGILVIDTPGHAAFTSLRKRGGALADIAVLIVDINEGFMPQTIEALNILKQ
HHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHC
NKTPFVVAANKIDRLPGWSSVDGAFITNFNEQKQHPNALTEFEIKLYENVIAPLAERGFE
CCCCEEEECCHHHCCCCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
ADLFSRVKDVSKTINIVPISAMTGEGIPDLLVMISGLAQRFMEQNLKLNVEGYAKGTVLE
HHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
VKEERGLGKTMDAIIYDGVAKRGDYIVIGNPDGIVVSRIKALLKPKALDEMRDPRDKFKT
EHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCHHHHHHH
MNEISAATGLKISAPDLDNIIAGSPLRIVPKNMVEQAKAEIVEEIEETAIQLDEEGIIIK
HHHHHHHCCCEEECCCCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEEE
ADTLGSLEALATELRKVGAKIKKAEVGDVSKKDVIEASSYAQTNPLNGAIILFNSKLLAD
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCHHHHH
AKSEVEKYEIKTFEGDIIYKLVEDYEEWTKEMKELLKSDEFNRLTKPAILRIIPGCIFNK
HHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHCCC
TKPAICGVEVVYGTLRVGCSVVDEQGKRLGTVKEIKDKKQENIKEAKVGMEVPISIDGTV
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCEE
ILGRHIGEDDIMYVELPEPEVRILSHNYMGELRGDEREAFERYVELKRKLENNPFWGI
EEECCCCCCCEEEEECCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA