Click here to switch to the map view.

The map label for this gene is 150401287

Identifier: 150401287

GI number: 150401287

Start: 887225

End: 887998

Strand: Direct

Name: 150401287

Synonym: Maeo_0859

Alternate gene names: NA

Gene position: 887225-887998 (Clockwise)

Preceding gene: 150401284

Following gene: 150401290

Centisome position: 56.53

GC content: 24.68

Gene sequence:

>774_bases
ATGGATAAATTAAACAATTTAAAAACTACATTAAAAGAGTTAGGTATAGAATCTGCAAAAACGATTGAAGAAACCGTAGA
TTTACAATATCATTATTTAGAAAATCTGCAAAAATCATTAAATAATGACGAATTATTTTTAAAATTAGTAATAATTAATG
CCCTTACGAGCTATCAACTTTCAACAACTGGCGAAAACTGGTGGAAGGAATTTTCAGAATATAACTGGGACAATACCATT
AAAAATAAAGAGAAAGATAATGGCGATTTATTTGAAAATTATATATTATTTTTAAGTAATTCAAATGGAAATAGACGCAT
TAACAATGTAAAAATAAAAAGAATTAATAAAATAAAACCATTTTTAAATAATTTACCCATTGCAGATTTGGAAAATTATT
ATTTAAATATGAATTCATTCAGGGATAATCTGGCAAAGCAATTAAACACAAAAAAGGATTCAAAAACCGTAGTATTTGCT
ATTAAAATGTTTGGATATGCTTCAAGGATAGTTTTTAAAAGATTTATTCCTTATCCTTTTGAGATTGAGATACCAAAAGA
CAGCAGGATAGAAAAATACACCAAAAAATTTACAGAACAAAATCCAATTGAATTTTGGAACAATATTTCAAAAGAAACGG
AAATTCCTCCTCTTCATATAGATTCTATATTGTGGTCAGCTTTGGGAAATTCAAAAACTGTAAAAATTCGTTTAAAATCG
TTGGAAAATAAAGAAATAAGTAAAAAAATAGATAATTTAATAAATATTCAATAA

Upstream 100 bases:

>100_bases
TATATACATATCGGTGCAAAAAGTTCTCGAATAGACTATATGGTGTATAGTGAAAATATATAGGGGAGCTCCCAAAAAGC
ATAACCCATTGTGTGATAAA

Downstream 100 bases:

>100_bases
TTTATTTATTCATTAATTTCTCAAAGCATTCCATGCATACAACCTTTCCGTCGATTAATCTCCCCTTAATTTCCATAAAA
TACTCCCCACACTCATCACA

Product: N-glycosylase/DNA lyase

Products: NA

Alternate protein names: 8-oxoguanine DNA glycosylase; AGOG; DNA-(apurinic or apyrimidinic site) lyase; AP lyase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDKLNNLKTTLKELGIESAKTIEETVDLQYHYLENLQKSLNNDELFLKLVIINALTSYQLSTTGENWWKEFSEYNWDNTI
KNKEKDNGDLFENYILFLSNSNGNRRINNVKIKRINKIKPFLNNLPIADLENYYLNMNSFRDNLAKQLNTKKDSKTVVFA
IKMFGYASRIVFKRFIPYPFEIEIPKDSRIEKYTKKFTEQNPIEFWNNISKETEIPPLHIDSILWSALGNSKTVKIRLKS
LENKEISKKIDNLINIQ

Sequences:

>Translated_257_residues
MDKLNNLKTTLKELGIESAKTIEETVDLQYHYLENLQKSLNNDELFLKLVIINALTSYQLSTTGENWWKEFSEYNWDNTI
KNKEKDNGDLFENYILFLSNSNGNRRINNVKIKRINKIKPFLNNLPIADLENYYLNMNSFRDNLAKQLNTKKDSKTVVFA
IKMFGYASRIVFKRFIPYPFEIEIPKDSRIEKYTKKFTEQNPIEFWNNISKETEIPPLHIDSILWSALGNSKTVKIRLKS
LENKEISKKIDNLINIQ
>Mature_257_residues
MDKLNNLKTTLKELGIESAKTIEETVDLQYHYLENLQKSLNNDELFLKLVIINALTSYQLSTTGENWWKEFSEYNWDNTI
KNKEKDNGDLFENYILFLSNSNGNRRINNVKIKRINKIKPFLNNLPIADLENYYLNMNSFRDNLAKQLNTKKDSKTVVFA
IKMFGYASRIVFKRFIPYPFEIEIPKDSRIEKYTKKFTEQNPIEFWNNISKETEIPPLHIDSILWSALGNSKTVKIRLKS
LENKEISKKIDNLINIQ

Specific function: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates [H]

COG id: COG4047

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR023170
- InterPro:   IPR015254
- InterPro:   IPR016544 [H]

Pfam domain/function: PF09171 DUF1886 [H]

EC number: =4.2.99.18 [H]

Molecular weight: Translated: 30328; Mature: 30328

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLNNLKTTLKELGIESAKTIEETVDLQYHYLENLQKSLNNDELFLKLVIINALTSYQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEE
STTGENWWKEFSEYNWDNTIKNKEKDNGDLFENYILFLSNSNGNRRINNVKIKRINKIKP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCCEECCEEEEHHHHHHH
FLNNLPIADLENYYLNMNSFRDNLAKQLNTKKDSKTVVFAIKMFGYASRIVFKRFIPYPF
HHHCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCE
EIEIPKDSRIEKYTKKFTEQNPIEFWNNISKETEIPPLHIDSILWSALGNSKTVKIRLKS
EEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
LENKEISKKIDNLINIQ
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKLNNLKTTLKELGIESAKTIEETVDLQYHYLENLQKSLNNDELFLKLVIINALTSYQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEE
STTGENWWKEFSEYNWDNTIKNKEKDNGDLFENYILFLSNSNGNRRINNVKIKRINKIKP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCCEECCEEEEHHHHHHH
FLNNLPIADLENYYLNMNSFRDNLAKQLNTKKDSKTVVFAIKMFGYASRIVFKRFIPYPF
HHHCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCE
EIEIPKDSRIEKYTKKFTEQNPIEFWNNISKETEIPPLHIDSILWSALGNSKTVKIRLKS
EEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
LENKEISKKIDNLINIQ
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA