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The map label for this gene is mer [H]

Identifier: 150401178

GI number: 150401178

Start: 770547

End: 771518

Strand: Reverse

Name: mer [H]

Synonym: Maeo_0749

Alternate gene names: 150401178

Gene position: 771518-770547 (Counterclockwise)

Preceding gene: 150401184

Following gene: 150401175

Centisome position: 49.16

GC content: 37.55

Gene sequence:

>972_bases
ATGAAATTTGGTATTGAATTTGTTCCTAATGAACCCATAACAAAATTAAGTTACTATGTAAAATTGGCAGAAGATAATGG
ATTTGAATACTGCTGGATTACAGACCACTACAACAACAGAAATGTATATATGGCATTAACAGCAATCGCAGCAGCTACAA
ACAAAATTAAAATAGGACCTGGTGTAACCAACCCCTATGTAAGAAGCCCAGCTGTTACAGCATCAGCAATGATTACATTG
GACGAAGTATCAACAGGAAGAGCTGTTTTAGGAATAGGTCCCGGAGATAAAGCTACATTTGATGCTTTGGGAATTGAATG
GACAAAACCTGTATCCACAATTAAAAAAGCTATTGCAGATATGAAAGCTTTAATGGATGGAGAAAGATTAGAAGAAGGAG
CAGTTTTAGCAATTAAGCCATCAACAAAAATCCCAATTTACATGGGAGCTCAAGGACCAAAAATGCTTGAAACAGCAGGT
ATGATTTCAGATGGTGTATTAATTAACGCATCAAATCCAAAAGACTTCGAAGCAGCAGTTCCATTAATTAGAAAAGGGGC
AGAAGCAGCAGGAAGAAGCATGGATGAAGTAGATGTTGCAGCTTATGCTTGTATGTCAGTTGATAAAAACGCAGATAAAG
CAAAAGGAGCAGCAAGCCCAGTTGTAGCTTTCATTGCAGCAGGTTCGCCACCAATGGTTTTAGAAAGGCATGGAATTGAC
CAAGAAAAAGTAGCAACAATTAGTGCAGCATTGAAAAAAGGAGACTTCGGAACAGCATTTGGAACAGTAGATGATACAAT
GTTAGAAGCATTCTCCTTATACGGAACACCTGATGAAGTAGTTGAAAAAATAGCAGCTCTTGGAAAAATGGGAGTAACAC
AAATTGTTGCAGGTTCCCCAATTGGACCAAACAAAGACACCAGCATTAAATTAATCGGTAAAAAAGTTGTTCCAGCAGTT
AAAGATTTATAA

Upstream 100 bases:

>100_bases
CATAATAATACATAAATATTATGGCATAATATGAATAAATTTTAAGTCTCATTTAAGGGTTGCTTCACTGCCATAAATAA
TTTAAAACCAAGGTGAAAAA

Downstream 100 bases:

>100_bases
TCTTTTAACGGATTTATCTTTTAATTTTTTTGTTTTTAAAATAATTTTTTAAAATAATTTTGATAATCTAAATAAAAATA
AAATAAGATAAATGATAGTT

Product: methylenetetrahydromethanopterin reductase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKFGIEFVPNEPITKLSYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAAATNKIKIGPGVTNPYVRSPAVTASAMITL
DEVSTGRAVLGIGPGDKATFDALGIEWTKPVSTIKKAIADMKALMDGERLEEGAVLAIKPSTKIPIYMGAQGPKMLETAG
MISDGVLINASNPKDFEAAVPLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAKGAASPVVAFIAAGSPPMVLERHGID
QEKVATISAALKKGDFGTAFGTVDDTMLEAFSLYGTPDEVVEKIAALGKMGVTQIVAGSPIGPNKDTSIKLIGKKVVPAV
KDL

Sequences:

>Translated_323_residues
MKFGIEFVPNEPITKLSYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAAATNKIKIGPGVTNPYVRSPAVTASAMITL
DEVSTGRAVLGIGPGDKATFDALGIEWTKPVSTIKKAIADMKALMDGERLEEGAVLAIKPSTKIPIYMGAQGPKMLETAG
MISDGVLINASNPKDFEAAVPLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAKGAASPVVAFIAAGSPPMVLERHGID
QEKVATISAALKKGDFGTAFGTVDDTMLEAFSLYGTPDEVVEKIAALGKMGVTQIVAGSPIGPNKDTSIKLIGKKVVPAV
KDL
>Mature_323_residues
MKFGIEFVPNEPITKLSYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAAATNKIKIGPGVTNPYVRSPAVTASAMITL
DEVSTGRAVLGIGPGDKATFDALGIEWTKPVSTIKKAIADMKALMDGERLEEGAVLAIKPSTKIPIYMGAQGPKMLETAG
MISDGVLINASNPKDFEAAVPLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAKGAASPVVAFIAAGSPPMVLERHGID
QEKVATISAALKKGDFGTAFGTVDDTMLEAFSLYGTPDEVVEKIAALGKMGVTQIVAGSPIGPNKDTSIKLIGKKVVPAV
KDL

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 34016; Mature: 34016

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGIEFVPNEPITKLSYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAAATNKIKIGP
CCCCCEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCEEEEEEEEHHHCCCEEEECC
GVTNPYVRSPAVTASAMITLDEVSTGRAVLGIGPGDKATFDALGIEWTKPVSTIKKAIAD
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCEEHHCCCCCCCHHHHHHHHHHH
MKALMDGERLEEGAVLAIKPSTKIPIYMGAQGPKMLETAGMISDGVLINASNPKDFEAAV
HHHHHCCCHHCCCCEEEECCCCCCEEEECCCCCHHHHHHCCCCCCEEEECCCCCCHHHHH
PLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAKGAASPVVAFIAAGSPPMVLERHGID
HHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
QEKVATISAALKKGDFGTAFGTVDDTMLEAFSLYGTPDEVVEKIAALGKMGVTQIVAGSP
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEEECCC
IGPNKDTSIKLIGKKVVPAVKDL
CCCCCCCEEEEECHHHCHHHHCC
>Mature Secondary Structure
MKFGIEFVPNEPITKLSYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAAATNKIKIGP
CCCCCEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCEEEEEEEEHHHCCCEEEECC
GVTNPYVRSPAVTASAMITLDEVSTGRAVLGIGPGDKATFDALGIEWTKPVSTIKKAIAD
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCEEHHCCCCCCCHHHHHHHHHHH
MKALMDGERLEEGAVLAIKPSTKIPIYMGAQGPKMLETAGMISDGVLINASNPKDFEAAV
HHHHHCCCHHCCCCEEEECCCCCCEEEECCCCCHHHHHHCCCCCCEEEECCCCCCHHHHH
PLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAKGAASPVVAFIAAGSPPMVLERHGID
HHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
QEKVATISAALKKGDFGTAFGTVDDTMLEAFSLYGTPDEVVEKIAALGKMGVTQIVAGSP
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEEECCC
IGPNKDTSIKLIGKKVVPAVKDL
CCCCCCCEEEEECHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]