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The map label for this gene is ygbD [C]

Identifier: 150401176

GI number: 150401176

Start: 768825

End: 770174

Strand: Direct

Name: ygbD [C]

Synonym: Maeo_0747

Alternate gene names: 150401176

Gene position: 768825-770174 (Clockwise)

Preceding gene: 150401174

Following gene: 150401177

Centisome position: 48.99

GC content: 36.0

Gene sequence:

>1350_bases
ATGAGAACTATAATAATAGGAAGTGGTGCTGCTGGACTCACTACTGCATCTACGATAAGAAGATACGATAAAGAAATGGA
AATAACCGTAATAACAATGGATAAATATATAGCATATTCCCCATGTGCTATACCTTATGCAATATGTGGCGAAATTCCAT
CATTTGACGATATAATAATGCACACACCAGAAGAATATAAAAAAAATAGATTAATTGATGTAATCACTGAATCCGAAGTA
TTAACAGTTAATTCAGAAAATAATAATATAACATATAAGGATAGCAATGGCAAAATAAATGAATTATCATATGATAACCT
GGTAATAGCAACAGGCGGTTCCTCGTTTATTCCTCCTATTGAGGGCATAGATTTAGAGGGGGTATTCAAACTAAGAACAA
TTGAAGACGGAATGAAAATAAAAGAATATGCTGAAAATTCGAAAAGTGCCGTAGTTGCAGGTGCAGGAGCTATTGGATTA
GAAATGGCATATGCCTTAAAAGTTATGGGTCTTGATGTGGTTGTAATTGAAATGGCTCCGCAAGTGCTTCCAAGAGCATT
AGATATTGACATGGCTGAAACCGTTAAAAAATATTTGGAAGATATTGGCATAAAATTCATAATTGGAAAACCATTGGCAA
AAATAATTGGAGAGGATAAGGTTAGAGCAATATATGCCGACGATAGAGAGATTGATACAGACATGATTATATTGGCAACA
GGAGTTAGATCAAATACGGAGCTCGCTAAAATGGCGGGCTGTGAAGTAGGAAGATGGGCAATAAAGGTAAATGAAAAAAT
GGAGACTTCAATACCTAATATATATGCTGTTGGAGATTGTGTCGAAGTTAAGGATTTTATAACTGGGCAGACAACTCTTT
CGCCATTTGGAACCACAGCAGTTAGGCAAGGTAAAGTTGCAGGTAAAAATATTGTAGGAATTGAAGCTAAATTTAATCCA
GTCTTAAATGCCATGGTATCAAAAATAGGAGATATTGAAATGGCTGGAACTGGTATGAGTGAGCTCGGTGCTCACCAAAA
TAGGCTCAAAGTAGTAGTTGGAAAATCAAAGGCACTAACCAGAGCAAGATACTACCCAGATGGAAAATTAATAGAAGTTA
AATTAATATGCGATAATAACAAGCACATTGTCGGATGCCAGATTGTAGGGGGCGAACGAGTTGCTGAAAGAGTAGACGCC
ATTTCAATAGCTATTGTAAATCATATGACTTGTAAAGAGCTCGCAGATATGGAATTCTGCTATGCGCCCCCTGTTTCGAT
GGTAATTGATCCATTAGCTCTTGCAGCTGAAAATGCATGCGATAAATTTAAAAAGATTAAAAAGGAATAA

Upstream 100 bases:

>100_bases
TAATTATTTGCACAAATATTATATATAATGGGGCCTACAAAGATATCAATATATTAATACCATTATTATTTCTATATATT
TTATTTTATAAGGTGAATTA

Downstream 100 bases:

>100_bases
AAATATATTATTATTTGTTTAATAATATATTAATAACAATTAATTATATTCAATAAATAAAGAAAAAATTAAAAAGGGGA
TATTATGGATATGGAAATGC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRTIIIGSGAAGLTTASTIRRYDKEMEITVITMDKYIAYSPCAIPYAICGEIPSFDDIIMHTPEEYKKNRLIDVITESEV
LTVNSENNNITYKDSNGKINELSYDNLVIATGGSSFIPPIEGIDLEGVFKLRTIEDGMKIKEYAENSKSAVVAGAGAIGL
EMAYALKVMGLDVVVIEMAPQVLPRALDIDMAETVKKYLEDIGIKFIIGKPLAKIIGEDKVRAIYADDREIDTDMIILAT
GVRSNTELAKMAGCEVGRWAIKVNEKMETSIPNIYAVGDCVEVKDFITGQTTLSPFGTTAVRQGKVAGKNIVGIEAKFNP
VLNAMVSKIGDIEMAGTGMSELGAHQNRLKVVVGKSKALTRARYYPDGKLIEVKLICDNNKHIVGCQIVGGERVAERVDA
ISIAIVNHMTCKELADMEFCYAPPVSMVIDPLALAAENACDKFKKIKKE

Sequences:

>Translated_449_residues
MRTIIIGSGAAGLTTASTIRRYDKEMEITVITMDKYIAYSPCAIPYAICGEIPSFDDIIMHTPEEYKKNRLIDVITESEV
LTVNSENNNITYKDSNGKINELSYDNLVIATGGSSFIPPIEGIDLEGVFKLRTIEDGMKIKEYAENSKSAVVAGAGAIGL
EMAYALKVMGLDVVVIEMAPQVLPRALDIDMAETVKKYLEDIGIKFIIGKPLAKIIGEDKVRAIYADDREIDTDMIILAT
GVRSNTELAKMAGCEVGRWAIKVNEKMETSIPNIYAVGDCVEVKDFITGQTTLSPFGTTAVRQGKVAGKNIVGIEAKFNP
VLNAMVSKIGDIEMAGTGMSELGAHQNRLKVVVGKSKALTRARYYPDGKLIEVKLICDNNKHIVGCQIVGGERVAERVDA
ISIAIVNHMTCKELADMEFCYAPPVSMVIDPLALAAENACDKFKKIKKE
>Mature_449_residues
MRTIIIGSGAAGLTTASTIRRYDKEMEITVITMDKYIAYSPCAIPYAICGEIPSFDDIIMHTPEEYKKNRLIDVITESEV
LTVNSENNNITYKDSNGKINELSYDNLVIATGGSSFIPPIEGIDLEGVFKLRTIEDGMKIKEYAENSKSAVVAGAGAIGL
EMAYALKVMGLDVVVIEMAPQVLPRALDIDMAETVKKYLEDIGIKFIIGKPLAKIIGEDKVRAIYADDREIDTDMIILAT
GVRSNTELAKMAGCEVGRWAIKVNEKMETSIPNIYAVGDCVEVKDFITGQTTLSPFGTTAVRQGKVAGKNIVGIEAKFNP
VLNAMVSKIGDIEMAGTGMSELGAHQNRLKVVVGKSKALTRARYYPDGKLIEVKLICDNNKHIVGCQIVGGERVAERVDA
ISIAIVNHMTCKELADMEFCYAPPVSMVIDPLALAAENACDKFKKIKKE

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=340, Percent_Identity=26.1764705882353, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226437568, Length=340, Percent_Identity=26.1764705882353, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI65787454, Length=340, Percent_Identity=26.1764705882353, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI22202629, Length=284, Percent_Identity=26.056338028169, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4757732, Length=284, Percent_Identity=26.056338028169, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI91199540, Length=387, Percent_Identity=24.031007751938, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789065, Length=332, Percent_Identity=27.1084337349398, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789765, Length=409, Percent_Identity=29.8288508557457, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788892, Length=281, Percent_Identity=23.4875444839858, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786307, Length=338, Percent_Identity=28.698224852071, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082354, Length=356, Percent_Identity=24.1573033707865, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=371, Percent_Identity=26.1455525606469, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32565766, Length=207, Percent_Identity=25.1207729468599, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639257, Length=348, Percent_Identity=26.4367816091954, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281359715, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281359713, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639250, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18543267, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639252, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24585130, Length=328, Percent_Identity=22.8658536585366, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358499, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48905; Mature: 48905

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIIIGSGAAGLTTASTIRRYDKEMEITVITMDKYIAYSPCAIPYAICGEIPSFDDIIM
CEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEECCEEEECCCCCCHHHHCCCCCCCHHEE
HTPEEYKKNRLIDVITESEVLTVNSENNNITYKDSNGKINELSYDNLVIATGGSSFIPPI
CCCHHHHCCCEEEEEECCEEEEEECCCCEEEEECCCCEEEEEECCCEEEECCCCCCCCCC
EGIDLEGVFKLRTIEDGMKIKEYAENSKSAVVAGAGAIGLEMAYALKVMGLDVVVIEMAP
CCCCCCCEEEEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCH
QVLPRALDIDMAETVKKYLEDIGIKFIIGKPLAKIIGEDKVRAIYADDREIDTDMIILAT
HHCCHHCCCCHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCEEEEEE
GVRSNTELAKMAGCEVGRWAIKVNEKMETSIPNIYAVGDCVEVKDFITGQTTLSPFGTTA
CCCCCCHHHHHHCCCCCEEEEEECCCHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCHH
VRQGKVAGKNIVGIEAKFNPVLNAMVSKIGDIEMAGTGMSELGAHQNRLKVVVGKSKALT
HHCCCCCCCEEEEEEECCHHHHHHHHHHCCCEEECCCCHHHHCCCCCCEEEEEECCHHHH
RARYYPDGKLIEVKLICDNNKHIVGCQIVGGERVAERVDAISIAIVNHMTCKELADMEFC
HHEECCCCCEEEEEEEECCCCEEEEEEEECCHHHHHHHHHEEEEEECCCHHHHHHCCCEE
YAPPVSMVIDPLALAAENACDKFKKIKKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTIIIGSGAAGLTTASTIRRYDKEMEITVITMDKYIAYSPCAIPYAICGEIPSFDDIIM
CEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEECCEEEECCCCCCHHHHCCCCCCCHHEE
HTPEEYKKNRLIDVITESEVLTVNSENNNITYKDSNGKINELSYDNLVIATGGSSFIPPI
CCCHHHHCCCEEEEEECCEEEEEECCCCEEEEECCCCEEEEEECCCEEEECCCCCCCCCC
EGIDLEGVFKLRTIEDGMKIKEYAENSKSAVVAGAGAIGLEMAYALKVMGLDVVVIEMAP
CCCCCCCEEEEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCH
QVLPRALDIDMAETVKKYLEDIGIKFIIGKPLAKIIGEDKVRAIYADDREIDTDMIILAT
HHCCHHCCCCHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCEEEEEE
GVRSNTELAKMAGCEVGRWAIKVNEKMETSIPNIYAVGDCVEVKDFITGQTTLSPFGTTA
CCCCCCHHHHHHCCCCCEEEEEECCCHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCHH
VRQGKVAGKNIVGIEAKFNPVLNAMVSKIGDIEMAGTGMSELGAHQNRLKVVVGKSKALT
HHCCCCCCCEEEEEEECCHHHHHHHHHHCCCEEECCCCHHHHCCCCCCEEEEEECCHHHH
RARYYPDGKLIEVKLICDNNKHIVGCQIVGGERVAERVDAISIAIVNHMTCKELADMEFC
HHEECCCCCEEEEEEEECCCCEEEEEEEECCHHHHHHHHHEEEEEECCCHHHHHHCCCEE
YAPPVSMVIDPLALAAENACDKFKKIKKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]