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The map label for this gene is 150401123

Identifier: 150401123

GI number: 150401123

Start: 711478

End: 712509

Strand: Direct

Name: 150401123

Synonym: Maeo_0693

Alternate gene names: NA

Gene position: 711478-712509 (Clockwise)

Preceding gene: 150401122

Following gene: 150401124

Centisome position: 45.33

GC content: 37.6

Gene sequence:

>1032_bases
ATGAAAATATCCGTATATGGTGCAGGTAATCAGGATTTATATATAAATAAGCTAAATTTGCCAGAAAACTATGGTGGGGA
AGCCCCCTATGGGGGAAGTAGGATGGCAATAGAATTTGCCAAAGCAGGGCATGATGTAATTCTTGCAGAGCCGAATAAAA
ATATGTTAACAGAAGAACAGTGGAAAATTGTAGAGGATGCGGGTGTTAAAGTTATATCCGACGACATAGAAGCTGCAAAA
CATGCTGAAATAGCAGTGTTTTTCACACCATTTGGGAAAAGGACAATAGAAATAGCAAAAAATATAATGCCTCATTTACC
ACAAAATGCAGTAATCGCAAATACTTGTACAGTATCGCCCCCCATATTATATGCTGCATTGGAGGTGGAGCTCCGAACTA
AAAGAAAAGATATAGGTATCTCATCTATGCATCCTGCAGCAGTTCCCGGAACCCCACAGCATGAGCATTATGTGATAAGT
GGAATATCAACAAACGGGACAGCTTATGCATCAGAAGAACAAATAAATAAATGTGTTCAATTGGTGGAAAGTGTAGGTAA
AAAAGTATATATTGTTCCAGCCGATGTTTCTTCAACTGTTGCTGATATGGGTTCCCTTGTAACTGCGGTTACTCTTGCAG
GGATTTTAGACTATTACAGTATAGGTAAAAAAATAATAAAAGCACCTGAAAAAATGATTGAGCAGCAAATTATCATGACA
TTGCAAACCATGGCTTCACTTGTAGAGACCTCTGGCGTTAGGGGGTTATTGAAAGCTATTAACCCAGAACTATTAGTTAG
AAGTTCTTCGTCAATGCACATAATAGAACAGCAAAAAGAATTGAGTGAATCATTGGAAGTATTAAAAAATTTAGATGAAA
ACTTGTCAAAAGAATCCCAAAATGCCACCATAAATCCAACCACTCTTGTTGCATCTCAGGCACTCGTAAAAGAAATAGAG
ACACTTATAGGAGGGGCTGCGGCAAATGGTGCTATTAAAAGAAGCATGCGAAAACTATTCACTGATAAATAA

Upstream 100 bases:

>100_bases
TATTAAAAATCAAATAGTAAATAATATATAAACTAAATAACCTATATAACAATATATAAAATAAACATTATTTCATTAAA
TTCAATATTTTGGTGATATT

Downstream 100 bases:

>100_bases
TAAAATAAGTAATTGGGGCTATCGTATCATGTCAAAAGAGCCAAAAATCGTTGTTATGGGTTCCGAAAATGTGGGTAAAA
CTACAATTATGGAAAAATTA

Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein

Products: 5,10-methenyltetrahydromethanopterin; reduced coenzyme F420

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKISVYGAGNQDLYINKLNLPENYGGEAPYGGSRMAIEFAKAGHDVILAEPNKNMLTEEQWKIVEDAGVKVISDDIEAAK
HAEIAVFFTPFGKRTIEIAKNIMPHLPQNAVIANTCTVSPPILYAALEVELRTKRKDIGISSMHPAAVPGTPQHEHYVIS
GISTNGTAYASEEQINKCVQLVESVGKKVYIVPADVSSTVADMGSLVTAVTLAGILDYYSIGKKIIKAPEKMIEQQIIMT
LQTMASLVETSGVRGLLKAINPELLVRSSSSMHIIEQQKELSESLEVLKNLDENLSKESQNATINPTTLVASQALVKEIE
TLIGGAAANGAIKRSMRKLFTDK

Sequences:

>Translated_343_residues
MKISVYGAGNQDLYINKLNLPENYGGEAPYGGSRMAIEFAKAGHDVILAEPNKNMLTEEQWKIVEDAGVKVISDDIEAAK
HAEIAVFFTPFGKRTIEIAKNIMPHLPQNAVIANTCTVSPPILYAALEVELRTKRKDIGISSMHPAAVPGTPQHEHYVIS
GISTNGTAYASEEQINKCVQLVESVGKKVYIVPADVSSTVADMGSLVTAVTLAGILDYYSIGKKIIKAPEKMIEQQIIMT
LQTMASLVETSGVRGLLKAINPELLVRSSSSMHIIEQQKELSESLEVLKNLDENLSKESQNATINPTTLVASQALVKEIE
TLIGGAAANGAIKRSMRKLFTDK
>Mature_343_residues
MKISVYGAGNQDLYINKLNLPENYGGEAPYGGSRMAIEFAKAGHDVILAEPNKNMLTEEQWKIVEDAGVKVISDDIEAAK
HAEIAVFFTPFGKRTIEIAKNIMPHLPQNAVIANTCTVSPPILYAALEVELRTKRKDIGISSMHPAAVPGTPQHEHYVIS
GISTNGTAYASEEQINKCVQLVESVGKKVYIVPADVSSTVADMGSLVTAVTLAGILDYYSIGKKIIKAPEKMIEQQIIMT
LQTMASLVETSGVRGLLKAINPELLVRSSSSMHIIEQQKELSESLEVLKNLDENLSKESQNATINPTTLVASQALVKEIE
TLIGGAAANGAIKRSMRKLFTDK

Specific function: Unknown

COG id: COG4007

COG function: function code R; Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR010063
- InterPro:   IPR004889
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03201 HMD [H]

EC number: 1.5.99.9

Molecular weight: Translated: 37145; Mature: 37145

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVYGAGNQDLYINKLNLPENYGGEAPYGGSRMAIEFAKAGHDVILAEPNKNMLTEEQ
CEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHH
WKIVEDAGVKVISDDIEAAKHAEIAVFFTPFGKRTIEIAKNIMPHLPQNAVIANTCTVSP
HHHHHHCCCEEEEHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
PILYAALEVELRTKRKDIGISSMHPAAVPGTPQHEHYVISGISTNGTAYASEEQINKCVQ
CCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHH
LVESVGKKVYIVPADVSSTVADMGSLVTAVTLAGILDYYSIGKKIIKAPEKMIEQQIIMT
HHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTMASLVETSGVRGLLKAINPELLVRSSSSMHIIEQQKELSESLEVLKNLDENLSKESQ
HHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NATINPTTLVASQALVKEIETLIGGAAANGAIKRSMRKLFTDK
CCCCCHHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKISVYGAGNQDLYINKLNLPENYGGEAPYGGSRMAIEFAKAGHDVILAEPNKNMLTEEQ
CEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHH
WKIVEDAGVKVISDDIEAAKHAEIAVFFTPFGKRTIEIAKNIMPHLPQNAVIANTCTVSP
HHHHHHCCCEEEEHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
PILYAALEVELRTKRKDIGISSMHPAAVPGTPQHEHYVISGISTNGTAYASEEQINKCVQ
CCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHH
LVESVGKKVYIVPADVSSTVADMGSLVTAVTLAGILDYYSIGKKIIKAPEKMIEQQIIMT
HHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTMASLVETSGVRGLLKAINPELLVRSSSSMHIIEQQKELSESLEVLKNLDENLSKESQ
HHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NATINPTTLVASQALVKEIETLIGGAAANGAIKRSMRKLFTDK
CCCCCHHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydromethanopterin; coenzyme F420

Specific reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]