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The map label for this gene is aroC

Identifier: 150401119

GI number: 150401119

Start: 707642

End: 708763

Strand: Direct

Name: aroC

Synonym: Maeo_0689

Alternate gene names: 150401119

Gene position: 707642-708763 (Clockwise)

Preceding gene: 150401118

Following gene: 150401120

Centisome position: 45.09

GC content: 34.58

Gene sequence:

>1122_bases
ATTAACACAATAGGCAAATCTTTTAGAATTACGGCATGGGGGGAAAGTCATGGAAAGGCATTAGGTGCTGTCGTAGACGG
ATGTCCTTCAAATTTACCACTAACAGGGGAGGACATTCAAAAGGAGTTAAACAGAAGAAGGCCAGGATATAGCTTATTTT
CCACACCAAGAAAGGAGGGGGACAAGGTAGAAATATTGTCTGGAATTTTTGAGGGAAAAACTACTGGAACTCCCATATCT
GCAATAGTATATAATACAAATCAAAAATCAAAAGATTACAGTCATTTGAAAAATACACCAAGACCGGGACATGCTGATTT
ATCGTATAAATTAAAATATGGAAATTATGATTATAGGGGAGGGGGTAGAAGTAGTGGAAGAACAACAATAGGGCACACAA
TAGGGGGAGCAATAGCAAAAAAACTATTGGATTATACTCACAATATAAAAATAATAGGATATACCACAAAAATAGGGAAT
ATCGAAGGAGATTTTAATTATTATAATAGTATTGAAAATAATGAAAAAATGATAAATGAGGAATTAATAAATAAAATAGA
AAATAATCCATTAAGATGCCCTTCCTCAAATGCCGATGAAATGAAAGATTTTGTATTAAATGCAATGGAAAATAAAAACA
GTGTCGGAGGAGTAATTGAATTAATTGCCCTAAATGTTCCAGTTGGAGTTGGAAACCCAATATTTGGTAAATTAAATGGG
GAGCTCTCAAATGCAATAATGAATATTAATGCCGTTAAAGGTGTGGAGATAGGTAGGGGATTTGAAAGTGCGGAGCTCCT
TGGAAGTGAAATGAATGATGAATATTATTATGATGAAAACAATAATATAAAATTAAAAACAAATAATTGTGGTGGTGTGT
TGGGCGGCATAAGTTGCGGAGCTCCCTTAGTAATCAGGGTGGCAGTTAAACCAACGCCATCAATATCCGCAGTCCAAAGC
ACCATAAATATAGAAAATAAAACAACAGAAAATCTTGAAATAGGGGGACGACATGACCCAATAATTGTTCCCAGAGTAAT
ACCTGTTTTGGAATCAATGGTGGCAATTGCGTTAAGTGATTTAATGATTAGAGGTGGATTTATTCACCCCTGTAAATTAT
AA

Upstream 100 bases:

>100_bases
AGCATTACAGCAAATACAGCAAGATACGATAGGACACATAGAGAACATACACTTTTCAAACACACCATAATAAAAAGAAA
AAAGAAAAAAAGGTGAAATT

Downstream 100 bases:

>100_bases
ATATTAGAAACGGGATATAATATTAATAATTAATTATTTATATTTTTATATTTTATTCTGATAATTTTAATTTTATATAT
TTATTTTTTACAACCATATA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNTIGKSFRITAWGESHGKALGAVVDGCPSNLPLTGEDIQKELNRRRPGYSLFSTPRKEGDKVEILSGIFEGKTTGTPIS
AIVYNTNQKSKDYSHLKNTPRPGHADLSYKLKYGNYDYRGGGRSSGRTTIGHTIGGAIAKKLLDYTHNIKIIGYTTKIGN
IEGDFNYYNSIENNEKMINEELINKIENNPLRCPSSNADEMKDFVLNAMENKNSVGGVIELIALNVPVGVGNPIFGKLNG
ELSNAIMNINAVKGVEIGRGFESAELLGSEMNDEYYYDENNNIKLKTNNCGGVLGGISCGAPLVIRVAVKPTPSISAVQS
TINIENKTTENLEIGGRHDPIIVPRVIPVLESMVAIALSDLMIRGGFIHPCKL

Sequences:

>Translated_373_residues
MNTIGKSFRITAWGESHGKALGAVVDGCPSNLPLTGEDIQKELNRRRPGYSLFSTPRKEGDKVEILSGIFEGKTTGTPIS
AIVYNTNQKSKDYSHLKNTPRPGHADLSYKLKYGNYDYRGGGRSSGRTTIGHTIGGAIAKKLLDYTHNIKIIGYTTKIGN
IEGDFNYYNSIENNEKMINEELINKIENNPLRCPSSNADEMKDFVLNAMENKNSVGGVIELIALNVPVGVGNPIFGKLNG
ELSNAIMNINAVKGVEIGRGFESAELLGSEMNDEYYYDENNNIKLKTNNCGGVLGGISCGAPLVIRVAVKPTPSISAVQS
TINIENKTTENLEIGGRHDPIIVPRVIPVLESMVAIALSDLMIRGGFIHPCKL
>Mature_373_residues
MNTIGKSFRITAWGESHGKALGAVVDGCPSNLPLTGEDIQKELNRRRPGYSLFSTPRKEGDKVEILSGIFEGKTTGTPIS
AIVYNTNQKSKDYSHLKNTPRPGHADLSYKLKYGNYDYRGGGRSSGRTTIGHTIGGAIAKKLLDYTHNIKIIGYTTKIGN
IEGDFNYYNSIENNEKMINEELINKIENNPLRCPSSNADEMKDFVLNAMENKNSVGGVIELIALNVPVGVGNPIFGKLNG
ELSNAIMNINAVKGVEIGRGFESAELLGSEMNDEYYYDENNNIKLKTNNCGGVLGGISCGAPLVIRVAVKPTPSISAVQS
TINIENKTTENLEIGGRHDPIIVPRVIPVLESMVAIALSDLMIRGGFIHPCKL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=44.2307692307692, Blast_Score=291, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321290, Length=366, Percent_Identity=42.896174863388, Blast_Score=299, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_META3 (A6UUV1)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324885.1
- ProteinModelPortal:   A6UUV1
- SMR:   A6UUV1
- STRING:   A6UUV1
- GeneID:   5326689
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0689
- eggNOG:   arNOG04618
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   MAEO419665:MAEO_0689-MONOMER
- HAMAP:   MF_00300_A
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 40501; Mature: 40501

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIGKSFRITAWGESHGKALGAVVDGCPSNLPLTGEDIQKELNRRRPGYSLFSTPRKEG
CCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCC
DKVEILSGIFEGKTTGTPISAIVYNTNQKSKDYSHLKNTPRPGHADLSYKLKYGNYDYRG
CEEHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEEECCEEECC
GGRSSGRTTIGHTIGGAIAKKLLDYTHNIKIIGYTTKIGNIEGDFNYYNSIENNEKMINE
CCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHCCCCCHHHHHHH
ELINKIENNPLRCPSSNADEMKDFVLNAMENKNSVGGVIELIALNVPVGVGNPIFGKLNG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEECCC
ELSNAIMNINAVKGVEIGRGFESAELLGSEMNDEYYYDENNNIKLKTNNCGGVLGGISCG
HHHHHEEEEECCCCEECCCCCCHHHHHCCCCCCCEEEECCCEEEEEECCCCCEECCCCCC
APLVIRVAVKPTPSISAVQSTINIENKTTENLEIGGRHDPIIVPRVIPVLESMVAIALSD
CCEEEEEEECCCCCHHHHHHHEECCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHH
LMIRGGFIHPCKL
HHHCCCCCCCCCC
>Mature Secondary Structure
MNTIGKSFRITAWGESHGKALGAVVDGCPSNLPLTGEDIQKELNRRRPGYSLFSTPRKEG
CCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCC
DKVEILSGIFEGKTTGTPISAIVYNTNQKSKDYSHLKNTPRPGHADLSYKLKYGNYDYRG
CEEHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEEECCEEECC
GGRSSGRTTIGHTIGGAIAKKLLDYTHNIKIIGYTTKIGNIEGDFNYYNSIENNEKMINE
CCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHCCCCCHHHHHHH
ELINKIENNPLRCPSSNADEMKDFVLNAMENKNSVGGVIELIALNVPVGVGNPIFGKLNG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEECCC
ELSNAIMNINAVKGVEIGRGFESAELLGSEMNDEYYYDENNNIKLKTNNCGGVLGGISCG
HHHHHEEEEECCCCEECCCCCCHHHHHCCCCCCCEEEECCCEEEEEECCCCCEECCCCCC
APLVIRVAVKPTPSISAVQSTINIENKTTENLEIGGRHDPIIVPRVIPVLESMVAIALSD
CCEEEEEEECCCCCHHHHHHHEECCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHH
LMIRGGFIHPCKL
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA