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The map label for this gene is purQ [H]

Identifier: 150401108

GI number: 150401108

Start: 695963

End: 696643

Strand: Reverse

Name: purQ [H]

Synonym: Maeo_0678

Alternate gene names: 150401108

Gene position: 696643-695963 (Counterclockwise)

Preceding gene: 150401109

Following gene: 150401107

Centisome position: 44.39

GC content: 34.8

Gene sequence:

>681_bases
ATGGACATTGCAGTTGCAAAATTTTTAGGAACAAATTGTGATAATGATGTATGTCATGCTATAAAATTAGCAGGGGGAGC
TCCCCATTTAATATGGTTTTCCGAAAAAAATATAGATAATTATGCCGGTGCAGTTATTCCCGGAGGATTTTCCTACGGCG
ATTATTTAAGAGCTGGAGCAATAAGCTCAAAAACTCCTATTGTGGGAGCTCTGAAAAAAATGGTAGATGACGGAAAACCA
GTATTGGGTATTTGCAATGGAGCTCAAATAGGTTTAGAAGCTGGATTTTCCTACGGAACTCTTACAAATAATGAAAGTGC
AAGATTTATTTGTAAATGGGTATATATCAGAGTTGAAAATAACAACACACCATTCACAAAATACTACAATGTTGGAGATG
TTTTAAAAATACCTGTGGCACATGCAGAAGGTAGATTTTATGCAGATGAAGAAACCCTTCAAAAAATGTATGAAAAAAAC
ATGATTGTATTTAAATACTGTGATGAACATGGAAATATCACAGAGGAGGCCAATCCAAATGGTTCTGTTGATAATATTGC
AGGAGTATGCAACGAAAAAGGAAATTGTGTTTTATTAATGCCTCATCCTGAGAGGGCAAGTGAGGAGCTCCTTGGTTCAG
ATGATGGATTAAATATGTTTAAATCAATGATAAATAAATAG

Upstream 100 bases:

>100_bases
ACAAAAGAATTTTTAAAAGTGCTTTCTTCTGAATTAACAAGGGAAGAATAATAAATATTATTAAAAAAATAAAATCAAAT
CAATATACAAATGTGATAAT

Downstream 100 bases:

>100_bases
AAATAAATAGTAATTATTATATAATATTATAATAATATCATTATCTGTTAATAATATCATAAACAAGAGCATAGGGTTTA
ATAGTTTTAATTATCGAGGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDIAVAKFLGTNCDNDVCHAIKLAGGAPHLIWFSEKNIDNYAGAVIPGGFSYGDYLRAGAISSKTPIVGALKKMVDDGKP
VLGICNGAQIGLEAGFSYGTLTNNESARFICKWVYIRVENNNTPFTKYYNVGDVLKIPVAHAEGRFYADEETLQKMYEKN
MIVFKYCDEHGNITEEANPNGSVDNIAGVCNEKGNCVLLMPHPERASEELLGSDDGLNMFKSMINK

Sequences:

>Translated_226_residues
MDIAVAKFLGTNCDNDVCHAIKLAGGAPHLIWFSEKNIDNYAGAVIPGGFSYGDYLRAGAISSKTPIVGALKKMVDDGKP
VLGICNGAQIGLEAGFSYGTLTNNESARFICKWVYIRVENNNTPFTKYYNVGDVLKIPVAHAEGRFYADEETLQKMYEKN
MIVFKYCDEHGNITEEANPNGSVDNIAGVCNEKGNCVLLMPHPERASEELLGSDDGLNMFKSMINK
>Mature_226_residues
MDIAVAKFLGTNCDNDVCHAIKLAGGAPHLIWFSEKNIDNYAGAVIPGGFSYGDYLRAGAISSKTPIVGALKKMVDDGKP
VLGICNGAQIGLEAGFSYGTLTNNESARFICKWVYIRVENNNTPFTKYYNVGDVLKIPVAHAEGRFYADEETLQKMYEKN
MIVFKYCDEHGNITEEANPNGSVDNIAGVCNEKGNCVLLMPHPERASEELLGSDDGLNMFKSMINK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=243, Percent_Identity=28.8065843621399, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI48994899, Length=185, Percent_Identity=30.8108108108108, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17553022, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24582111, Length=233, Percent_Identity=31.3304721030043, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24582109, Length=233, Percent_Identity=31.3304721030043, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17137292, Length=233, Percent_Identity=31.3304721030043, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24687; Mature: 24687

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVAKFLGTNCDNDVCHAIKLAGGAPHLIWFSEKNIDNYAGAVIPGGFSYGDYLRAGA
CCEEHHHHHCCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCCEEECCCCCCHHHHHHCC
ISSKTPIVGALKKMVDDGKPVLGICNGAQIGLEAGFSYGTLTNNESARFICKWVYIRVEN
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEHHCCCCCCCEECCCCCCEEEEEEEEEEEEC
NNTPFTKYYNVGDVLKIPVAHAEGRFYADEETLQKMYEKNMIVFKYCDEHGNITEEANPN
CCCCEEEEECCCCEEEEEEEECCCCEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
GSVDNIAGVCNEKGNCVLLMPHPERASEELLGSDDGLNMFKSMINK
CCHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MDIAVAKFLGTNCDNDVCHAIKLAGGAPHLIWFSEKNIDNYAGAVIPGGFSYGDYLRAGA
CCEEHHHHHCCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCCEEECCCCCCHHHHHHCC
ISSKTPIVGALKKMVDDGKPVLGICNGAQIGLEAGFSYGTLTNNESARFICKWVYIRVEN
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEHHCCCCCCCEECCCCCCEEEEEEEEEEEEC
NNTPFTKYYNVGDVLKIPVAHAEGRFYADEETLQKMYEKNMIVFKYCDEHGNITEEANPN
CCCCEEEEECCCCEEEEEEEECCCCEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
GSVDNIAGVCNEKGNCVLLMPHPERASEELLGSDDGLNMFKSMINK
CCHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]