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The map label for this gene is argD [H]

Identifier: 150401070

GI number: 150401070

Start: 657328

End: 658539

Strand: Direct

Name: argD [H]

Synonym: Maeo_0640

Alternate gene names: 150401070

Gene position: 657328-658539 (Clockwise)

Preceding gene: 150401068

Following gene: 150401071

Centisome position: 41.88

GC content: 33.5

Gene sequence:

>1212_bases
ATGGATTATTTCTCTGAGATTTATGATAATATCGATGAAAAAACAATGATAAAAAATGATAAAAAATACATAATTGGAAC
ATATGGGAGATATGGAATCGTCCCAGTAAAGGGATATGGGATGATTGTAGAAGACATCAACGGAAAAAAATATAAGGATT
TTCTTGCTGGTATTGGCGTAAATAATGTAGGGCATTGCCATCCAGAAGTAGTTAAAACATTGCAAAAACAGGCGGAGCTC
CTTATTCATACATCAAATTTATACCACATAATACCACAAGTTCAACTCGGTAAAAAATTGGTGGAATTAACTGGAATGGA
TAAAGCCTTTTTCTCAAACAGTGGGGCTGAAGCCAATGAAGCCGCAATAAAACTTGCTCGAAAACATGGGAAAAACAACA
ACATAGGAGAGGGAGAAATTATTACTATGGAACATAGCTTCCACGGTAGAACTTTAACCACAATAACGGCAACGGCAAAA
CCAGCATATCAAGAAGGATATGAACCACTCCCAAAAGGATTTAAATATGTTAAATTTAATGATATTGAAGCACTAAAAGA
AGGCATATCAAATAAAACAACGGCAATAATGTTGGAACCTATTCAAGGGGAAGGGGGCATACATATAGCAGATAAAGAAT
ATTTAAAAGGAGTTAGAGACATCTGCAATGATAAAAATATAGTGTTAATATTTGATGAAGTTCAATGTGGTATGGGGAGA
ACAGGAAAAATGTTTGCATATGAACATTATAATATAAAACCAGACATATTAACATTGGCAAAAGCTCTCGGTGGTGGAGC
TCCGATAGGTGCAACAATTGCAACGGAAGAAGTGGCGACTGCCTTTACACCAGGAAGTCATGGAACCACATTTGGAGGAA
ATCCATTAGCCTGTTCTGCATCTTATGCATCAGTTAGAGTATTAGAAGGACTTTTAGAAAATACTCAAAATATGGGAGAA
TATTTTATAACTGAATTAAATAAATTAAAAAATAAATATGGATTTATTAAAGAGGTTAGAGGAATAGGATTAATGATAGG
AATAGAACTATCATTTAATGGTGGAGATATTGTTAAAAAAATGCTTGAAAAAGGTTATTTAATAAATTGCACATCAGATG
TGGTTTTAAGATTTTTGCCACCGCTTATCGTGGAAAAAACAGATATTGATGGATTGATTAATGCCTTAGATGAAGTATTT
TCAGAAATATAG

Upstream 100 bases:

>100_bases
GTATAGTATATGGTTTATAATGTATTGATGTATAATAGTTTAATGTATAATAGTACATAGAGACAATATATAATATATTT
TATAAATAAATGGTGATTTT

Downstream 100 bases:

>100_bases
TCAATCTTTAATTAAATATCATTTATTAGTCAAGGTACCTAAGCATTCTTTAACTGTATTTTATAGTTTAAAGGAATATT
TGCTTTTATTCAACACCAAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MDYFSEIYDNIDEKTMIKNDKKYIIGTYGRYGIVPVKGYGMIVEDINGKKYKDFLAGIGVNNVGHCHPEVVKTLQKQAEL
LIHTSNLYHIIPQVQLGKKLVELTGMDKAFFSNSGAEANEAAIKLARKHGKNNNIGEGEIITMEHSFHGRTLTTITATAK
PAYQEGYEPLPKGFKYVKFNDIEALKEGISNKTTAIMLEPIQGEGGIHIADKEYLKGVRDICNDKNIVLIFDEVQCGMGR
TGKMFAYEHYNIKPDILTLAKALGGGAPIGATIATEEVATAFTPGSHGTTFGGNPLACSASYASVRVLEGLLENTQNMGE
YFITELNKLKNKYGFIKEVRGIGLMIGIELSFNGGDIVKKMLEKGYLINCTSDVVLRFLPPLIVEKTDIDGLINALDEVF
SEI

Sequences:

>Translated_403_residues
MDYFSEIYDNIDEKTMIKNDKKYIIGTYGRYGIVPVKGYGMIVEDINGKKYKDFLAGIGVNNVGHCHPEVVKTLQKQAEL
LIHTSNLYHIIPQVQLGKKLVELTGMDKAFFSNSGAEANEAAIKLARKHGKNNNIGEGEIITMEHSFHGRTLTTITATAK
PAYQEGYEPLPKGFKYVKFNDIEALKEGISNKTTAIMLEPIQGEGGIHIADKEYLKGVRDICNDKNIVLIFDEVQCGMGR
TGKMFAYEHYNIKPDILTLAKALGGGAPIGATIATEEVATAFTPGSHGTTFGGNPLACSASYASVRVLEGLLENTQNMGE
YFITELNKLKNKYGFIKEVRGIGLMIGIELSFNGGDIVKKMLEKGYLINCTSDVVLRFLPPLIVEKTDIDGLINALDEVF
SEI
>Mature_403_residues
MDYFSEIYDNIDEKTMIKNDKKYIIGTYGRYGIVPVKGYGMIVEDINGKKYKDFLAGIGVNNVGHCHPEVVKTLQKQAEL
LIHTSNLYHIIPQVQLGKKLVELTGMDKAFFSNSGAEANEAAIKLARKHGKNNNIGEGEIITMEHSFHGRTLTTITATAK
PAYQEGYEPLPKGFKYVKFNDIEALKEGISNKTTAIMLEPIQGEGGIHIADKEYLKGVRDICNDKNIVLIFDEVQCGMGR
TGKMFAYEHYNIKPDILTLAKALGGGAPIGATIATEEVATAFTPGSHGTTFGGNPLACSASYASVRVLEGLLENTQNMGE
YFITELNKLKNKYGFIKEVRGIGLMIGIELSFNGGDIVKKMLEKGYLINCTSDVVLRFLPPLIVEKTDIDGLINALDEVF
SEI

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=34.1145833333333, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI284507298, Length=288, Percent_Identity=35.7638888888889, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI13994255, Length=396, Percent_Identity=30.5555555555556, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=30.4878048780488, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=30.8093994778068, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226442705, Length=410, Percent_Identity=30, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=27.4939172749392, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI188536080, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679950, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679946, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1789759, Length=374, Percent_Identity=44.1176470588235, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI1788044, Length=383, Percent_Identity=43.0809399477807, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=38.2278481012658, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=35.7682619647355, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=33.0808080808081, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1786991, Length=419, Percent_Identity=28.1622911694511, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786349, Length=315, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=390, Percent_Identity=36.4102564102564, Blast_Score=261, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI25144274, Length=279, Percent_Identity=36.9175627240143, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=32.7790973871734, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=413, Percent_Identity=31.7191283292978, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17541228, Length=434, Percent_Identity=26.4976958525346, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71981843, Length=177, Percent_Identity=32.2033898305085, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=36.7901234567901, Blast_Score=260, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=409, Percent_Identity=35.9413202933985, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=25.2927400468384, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=483, Percent_Identity=25.2587991718427, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=36.8421052631579, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=30.4449648711944, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356575, Length=415, Percent_Identity=30.3614457831325, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28574759, Length=433, Percent_Identity=30.4849884526559, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.5901639344262, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.5901639344262, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.5901639344262, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44307; Mature: 44307

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFSEIYDNIDEKTMIKNDKKYIIGTYGRYGIVPVKGYGMIVEDINGKKYKDFLAGIGV
CCHHHHHHCCCCHHHHHCCCCCEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHCCC
NNVGHCHPEVVKTLQKQAELLIHTSNLYHIIPQVQLGKKLVELTGMDKAFFSNSGAEANE
CCCCCCCHHHHHHHHHHHHEEEEECCCEEECCCHHHHHHHHHHHCCCHHHHCCCCCCHHH
AAIKLARKHGKNNNIGEGEIITMEHSFHGRTLTTITATAKPAYQEGYEPLPKGFKYVKFN
HHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCEEEEEC
DIEALKEGISNKTTAIMLEPIQGEGGIHIADKEYLKGVRDICNDKNIVLIFDEVQCGMGR
CHHHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TGKMFAYEHYNIKPDILTLAKALGGGAPIGATIATEEVATAFTPGSHGTTFGGNPLACSA
CCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHEECCCCCCCCCCCCCCEECC
SYASVRVLEGLLENTQNMGEYFITELNKLKNKYGFIKEVRGIGLMIGIELSFNGGDIVKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHH
MLEKGYLINCTSDVVLRFLPPLIVEKTDIDGLINALDEVFSEI
HHHCCEEEECHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYFSEIYDNIDEKTMIKNDKKYIIGTYGRYGIVPVKGYGMIVEDINGKKYKDFLAGIGV
CCHHHHHHCCCCHHHHHCCCCCEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHCCC
NNVGHCHPEVVKTLQKQAELLIHTSNLYHIIPQVQLGKKLVELTGMDKAFFSNSGAEANE
CCCCCCCHHHHHHHHHHHHEEEEECCCEEECCCHHHHHHHHHHHCCCHHHHCCCCCCHHH
AAIKLARKHGKNNNIGEGEIITMEHSFHGRTLTTITATAKPAYQEGYEPLPKGFKYVKFN
HHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCEEEEEC
DIEALKEGISNKTTAIMLEPIQGEGGIHIADKEYLKGVRDICNDKNIVLIFDEVQCGMGR
CHHHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TGKMFAYEHYNIKPDILTLAKALGGGAPIGATIATEEVATAFTPGSHGTTFGGNPLACSA
CCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHEECCCCCCCCCCCCCCEECC
SYASVRVLEGLLENTQNMGEYFITELNKLKNKYGFIKEVRGIGLMIGIELSFNGGDIVKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHH
MLEKGYLINCTSDVVLRFLPPLIVEKTDIDGLINALDEVFSEI
HHHCCEEEECHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]