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The map label for this gene is speH

Identifier: 150401034

GI number: 150401034

Start: 618523

End: 618876

Strand: Reverse

Name: speH

Synonym: Maeo_0603

Alternate gene names: 150401034

Gene position: 618876-618523 (Counterclockwise)

Preceding gene: 150401035

Following gene: 150401033

Centisome position: 39.43

GC content: 38.7

Gene sequence:

>354_bases
TTGAAACATCTGGGAAAACATCTAATAATGGAGCTCTGGGATTGTGATAAACAGGCATTAGACAATCAGGCAGGGGTAGA
AAAAATGTTGGAGGATGCCACCAATTCATGCGGGGCAACACTTATTTGCATAAGAACCCATAAATTTTCGCCACAAGGAG
TTACGGGAGTTGCAGTTCTTGCGGAAAGTCATATTAGTATCCACACATGGCCAGAAATAGGATATGCGGCAATGGATATA
TTTACCTGTGGAGAGCATGTAAATCCAGAAGATGCTATTCCGGCAATAAGGGATTTTTTAAAACCTGCTAAATTTGATAT
AATAGATATAAAAAGAGGAAGTATGGTAGAATAA

Upstream 100 bases:

>100_bases
AAATATTGGCTGTGCCTTTGCAGCTGTTGCACTGTGGTATAAATAATATACAATATAAAATATACAATAAAATATATAAA
AAGAAAAAAGGTGAGATTAT

Downstream 100 bases:

>100_bases
ATTTATTATTTTTAAGTAAGTTAATAATTAAGGAGCTCCCCTTATATAGTTAATCTTCAATAATTGTCCCTTATCCGGCT
TATTATTAAATAAAAAGACC

Product: S-adenosylmethionine decarboxylase related

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MKHLGKHLIMELWDCDKQALDNQAGVEKMLEDATNSCGATLICIRTHKFSPQGVTGVAVLAESHISIHTWPEIGYAAMDI
FTCGEHVNPEDAIPAIRDFLKPAKFDIIDIKRGSMVE

Sequences:

>Translated_117_residues
MKHLGKHLIMELWDCDKQALDNQAGVEKMLEDATNSCGATLICIRTHKFSPQGVTGVAVLAESHISIHTWPEIGYAAMDI
FTCGEHVNPEDAIPAIRDFLKPAKFDIIDIKRGSMVE
>Mature_117_residues
MKHLGKHLIMELWDCDKQALDNQAGVEKMLEDATNSCGATLICIRTHKFSPQGVTGVAVLAESHISIHTWPEIGYAAMDI
FTCGEHVNPEDAIPAIRDFLKPAKFDIIDIKRGSMVE

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_META3 (A6UUL6)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324800.1
- ProteinModelPortal:   A6UUL6
- SMR:   A6UUL6
- STRING:   A6UUL6
- GeneID:   5326474
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0603
- eggNOG:   arNOG10813
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   CLSK876156
- BioCyc:   MAEO419665:MAEO_0603-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 12947; Mature: 12947

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLGKHLIMELWDCDKQALDNQAGVEKMLEDATNSCGATLICIRTHKFSPQGVTGVAVL
CCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHEEE
AESHISIHTWPEIGYAAMDIFTCGEHVNPEDAIPAIRDFLKPAKFDIIDIKRGSMVE
ECCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKHLGKHLIMELWDCDKQALDNQAGVEKMLEDATNSCGATLICIRTHKFSPQGVTGVAVL
CCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHEEE
AESHISIHTWPEIGYAAMDIFTCGEHVNPEDAIPAIRDFLKPAKFDIIDIKRGSMVE
ECCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA