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The map label for this gene is carA [H]

Identifier: 150400997

GI number: 150400997

Start: 583347

End: 584408

Strand: Reverse

Name: carA [H]

Synonym: Maeo_0566

Alternate gene names: 150400997

Gene position: 584408-583347 (Counterclockwise)

Preceding gene: 150401000

Following gene: 150400996

Centisome position: 37.24

GC content: 32.39

Gene sequence:

>1062_bases
ATGTATGGAATATTAGTTTTAGAAGACGGGACATTTTTAAAAGGAAAAGGATTCGGTGCAGAAGGCGAAGTTTTAGGAGA
ATTAGTATTTAATACCTGTATGACCGGATATGTGGAAATTCTAACAGACCCATCATATAGTGGTCAAATAATAACAATGA
CTTATCCATTGGAAGGAAACTATGGAGTAGATGAAGAATGGTTCGAATCTGATGGAATAAAAGCCGAAGGATTTGTTGTA
AAAGATATGACCAGTGAAAAATTAGATAATTTCTTAAAAGAATACAATATTCCCGGAATAAGTGATATTGACACAAGATT
TATTACAAAAAGAATTAGGTCAAAAGGAGTTGTAAAGGCACTTTTAAAAACTTCAACAGAACCAATAAACGAAAATGACA
TAAATAAATATGTGGAAATGGCTAAAAATCATAAAGATTTATCGGAAATTGATTTGGTGCCTAATGTATCTACAAAAGAA
ACAATAATCCATAAGGTAGAAGACGATAAAGAAATATCAAAATGTGTTTTAATTGATTGCGGAGTTAAAACAAGTATAAT
CGACTGCCTGTTGGAAAGAAATTGCACTGTGATACAGGTGCCATATAATACCCCTGCTAAGGAAATATTAAATTATGGTG
CTAATTTTGTACTGGTATCAAATGGTCCCGGCGACCCAGATAATATGGAAGATACTGTAAATATTGTAAAGGAGCTCCTT
GGAAAAATACCAATTACAGGAATTTGTTTAGGACATCAAATTATATCCTTAGCATTGGGTGGAAAAACTTATAAAATGAA
GTTTGGACATAGGGGAGGAAACCAGCCAGTGGAAGAAAATGGATTAGTATATATAACATCTCAGAATCATGGATATGCAT
CAGAAAACATATCAAAAGAAGGAATTAGTATTAATTCGATAAATCTAAATGATAATACTGTGGAAGGACTTAAAGGAGAT
AATTTACTATGTGTTCAATATCACCCGGAGGCAGCTCCTGGACCTCATGATGCCATGTTTTTGTTTGACGAATTTATTAA
ATTGGGACAAAATAATAAATAA

Upstream 100 bases:

>100_bases
GCGGTACGGAAAATTGTTCGAAGATTGACTATATGGTTTTTTATACTAATTTATAATTTTATAAATTTTATATTTATTAT
ACAATTTTTTGGTGGATTAT

Downstream 100 bases:

>100_bases
TAATATTTTTTAATAATATTTTTTTATGAATATTGGGTTTTTAAAAACCGTTTTTTTTTATAATTTATATTATTATTTTT
TACACTATTAAAAAAACGAT

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MYGILVLEDGTFLKGKGFGAEGEVLGELVFNTCMTGYVEILTDPSYSGQIITMTYPLEGNYGVDEEWFESDGIKAEGFVV
KDMTSEKLDNFLKEYNIPGISDIDTRFITKRIRSKGVVKALLKTSTEPINENDINKYVEMAKNHKDLSEIDLVPNVSTKE
TIIHKVEDDKEISKCVLIDCGVKTSIIDCLLERNCTVIQVPYNTPAKEILNYGANFVLVSNGPGDPDNMEDTVNIVKELL
GKIPITGICLGHQIISLALGGKTYKMKFGHRGGNQPVEENGLVYITSQNHGYASENISKEGISINSINLNDNTVEGLKGD
NLLCVQYHPEAAPGPHDAMFLFDEFIKLGQNNK

Sequences:

>Translated_353_residues
MYGILVLEDGTFLKGKGFGAEGEVLGELVFNTCMTGYVEILTDPSYSGQIITMTYPLEGNYGVDEEWFESDGIKAEGFVV
KDMTSEKLDNFLKEYNIPGISDIDTRFITKRIRSKGVVKALLKTSTEPINENDINKYVEMAKNHKDLSEIDLVPNVSTKE
TIIHKVEDDKEISKCVLIDCGVKTSIIDCLLERNCTVIQVPYNTPAKEILNYGANFVLVSNGPGDPDNMEDTVNIVKELL
GKIPITGICLGHQIISLALGGKTYKMKFGHRGGNQPVEENGLVYITSQNHGYASENISKEGISINSINLNDNTVEGLKGD
NLLCVQYHPEAAPGPHDAMFLFDEFIKLGQNNK
>Mature_353_residues
MYGILVLEDGTFLKGKGFGAEGEVLGELVFNTCMTGYVEILTDPSYSGQIITMTYPLEGNYGVDEEWFESDGIKAEGFVV
KDMTSEKLDNFLKEYNIPGISDIDTRFITKRIRSKGVVKALLKTSTEPINENDINKYVEMAKNHKDLSEIDLVPNVSTKE
TIIHKVEDDKEISKCVLIDCGVKTSIIDCLLERNCTVIQVPYNTPAKEILNYGANFVLVSNGPGDPDNMEDTVNIVKELL
GKIPITGICLGHQIISLALGGKTYKMKFGHRGGNQPVEENGLVYITSQNHGYASENISKEGISINSINLNDNTVEGLKGD
NLLCVQYHPEAAPGPHDAMFLFDEFIKLGQNNK

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=369, Percent_Identity=38.7533875338753, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI169790915, Length=374, Percent_Identity=37.9679144385027, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI21361331, Length=374, Percent_Identity=37.9679144385027, Blast_Score=223, Evalue=1e-58,
Organism=Escherichia coli, GI1786215, Length=373, Percent_Identity=39.9463806970509, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI193204318, Length=373, Percent_Identity=39.142091152815, Blast_Score=227, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6322331, Length=388, Percent_Identity=37.3711340206186, Blast_Score=216, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6324878, Length=375, Percent_Identity=36, Blast_Score=206, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24642586, Length=377, Percent_Identity=36.8700265251989, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI45555749, Length=377, Percent_Identity=36.8700265251989, Blast_Score=214, Evalue=6e-56,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 38956; Mature: 38956

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGILVLEDGTFLKGKGFGAEGEVLGELVFNTCMTGYVEILTDPSYSGQIITMTYPLEGN
CEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEECCCC
YGVDEEWFESDGIKAEGFVVKDMTSEKLDNFLKEYNIPGISDIDTRFITKRIRSKGVVKA
CCCCHHHHHCCCCEECCEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKTSTEPINENDINKYVEMAKNHKDLSEIDLVPNVSTKETIIHKVEDDKEISKCVLIDC
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEC
GVKTSIIDCLLERNCTVIQVPYNTPAKEILNYGANFVLVSNGPGDPDNMEDTVNIVKELL
CCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHH
GKIPITGICLGHQIISLALGGKTYKMKFGHRGGNQPVEENGLVYITSQNHGYASENISKE
HHCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
GISINSINLNDNTVEGLKGDNLLCVQYHPEAAPGPHDAMFLFDEFIKLGQNNK
CEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYGILVLEDGTFLKGKGFGAEGEVLGELVFNTCMTGYVEILTDPSYSGQIITMTYPLEGN
CEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEECCCC
YGVDEEWFESDGIKAEGFVVKDMTSEKLDNFLKEYNIPGISDIDTRFITKRIRSKGVVKA
CCCCHHHHHCCCCEECCEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKTSTEPINENDINKYVEMAKNHKDLSEIDLVPNVSTKETIIHKVEDDKEISKCVLIDC
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEC
GVKTSIIDCLLERNCTVIQVPYNTPAKEILNYGANFVLVSNGPGDPDNMEDTVNIVKELL
CCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHH
GKIPITGICLGHQIISLALGGKTYKMKFGHRGGNQPVEENGLVYITSQNHGYASENISKE
HHCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
GISINSINLNDNTVEGLKGDNLLCVQYHPEAAPGPHDAMFLFDEFIKLGQNNK
CEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA