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The map label for this gene is gsiC [H]

Identifier: 150400943

GI number: 150400943

Start: 532019

End: 532963

Strand: Reverse

Name: gsiC [H]

Synonym: Maeo_0511

Alternate gene names: 150400943

Gene position: 532963-532019 (Counterclockwise)

Preceding gene: 150400944

Following gene: 150400942

Centisome position: 33.96

GC content: 34.18

Gene sequence:

>945_bases
ATGAAAAATTTTATATTAAGGAGGTTATTTTTGGCAATACCAATGGCAATAGCTGTTTCATTGATTTCATTTTCATTACT
TTACTTTTCCCCGGGGAATCCCGCAGAAATCATATTGGAGCAGAAATCACCAGATTCCAGTCCTGATGAAAATGCAATTA
AAGAATATGAGAAAAAACTTGGACTAGATAAGCCTTTTTATGATTTATATGTAATATGGCTTAGCAAAGCATTAACAGGA
GATTTTGGAGTTTCCCTTCAAAATGGCGAGCCAGTTATAGATGAGTTTATGGCAAGATTTCCATATACTGTTATGATTAT
GGTCGGTGCTACTACTGTTTATTTTGTGCTGGGGGTTGTAATGGGTATATTATCTGCACTTAACAAAGATGGCATAATTG
ATAATATAGTCAGAGCTTATGCATCATTAAAAATGGCTATCCCAAGCTTTTGGTTGGCATTGTTGTTAATATGGGTATTT
TCTGTTAAACTTAAAATTATTAGTGCATTTGGATATAATGGGCTTGATAGTTTAATACTACCTTCCTTTGCTCTTGGTCT
AGGCATGGCAGGTTCTCTAGCAAGGGTTTTGAGAACATGCATCCTTGAAGTCATGAGTAGTGATTATATTTTAACTGCAA
GGGCGAAGGGACTTTCAAATAAGGTTGTTGTATTGAAACATGTATTAAAAAATGCCTTTCTACCAGTTATAACATTAATG
GGGATGAAAACAGCCTATTTACTTGGAGGTGCCGTCATAATTGAAAGTATATTTGGATGGCCAGGTATTGGAAGTTATTT
TATCGATATAATCAATGCAAAAGATTATCCTGCGGTTTCTGGACTTGTATTTATATTTGGAATTCTATTTGTTCTTGTTA
ATTTAATCGTGGATATATCTTATGCCATATTAGACCCGAGAGTGAGATACGATAAAGGTGTATAA

Upstream 100 bases:

>100_bases
GATGTGGGATATATTGATTTAAGCAATGTTGTAATTAAATAAAAAATAACTAAATAATCAAATAAACAAATTATCTCTTT
TTATTTTTTAAGGTGAGCTC

Downstream 100 bases:

>100_bases
AAAATGAACGCCAATAAAAAGTTTGCTTTATGTTTGGCAGGTGTTGCTGTCATATTTATTATTTCATTGCTCTCTCCATA
CATATTCAAAGATGTAAATG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKNFILRRLFLAIPMAIAVSLISFSLLYFSPGNPAEIILEQKSPDSSPDENAIKEYEKKLGLDKPFYDLYVIWLSKALTG
DFGVSLQNGEPVIDEFMARFPYTVMIMVGATTVYFVLGVVMGILSALNKDGIIDNIVRAYASLKMAIPSFWLALLLIWVF
SVKLKIISAFGYNGLDSLILPSFALGLGMAGSLARVLRTCILEVMSSDYILTARAKGLSNKVVVLKHVLKNAFLPVITLM
GMKTAYLLGGAVIIESIFGWPGIGSYFIDIINAKDYPAVSGLVFIFGILFVLVNLIVDISYAILDPRVRYDKGV

Sequences:

>Translated_314_residues
MKNFILRRLFLAIPMAIAVSLISFSLLYFSPGNPAEIILEQKSPDSSPDENAIKEYEKKLGLDKPFYDLYVIWLSKALTG
DFGVSLQNGEPVIDEFMARFPYTVMIMVGATTVYFVLGVVMGILSALNKDGIIDNIVRAYASLKMAIPSFWLALLLIWVF
SVKLKIISAFGYNGLDSLILPSFALGLGMAGSLARVLRTCILEVMSSDYILTARAKGLSNKVVVLKHVLKNAFLPVITLM
GMKTAYLLGGAVIIESIFGWPGIGSYFIDIINAKDYPAVSGLVFIFGILFVLVNLIVDISYAILDPRVRYDKGV
>Mature_314_residues
MKNFILRRLFLAIPMAIAVSLISFSLLYFSPGNPAEIILEQKSPDSSPDENAIKEYEKKLGLDKPFYDLYVIWLSKALTG
DFGVSLQNGEPVIDEFMARFPYTVMIMVGATTVYFVLGVVMGILSALNKDGIIDNIVRAYASLKMAIPSFWLALLLIWVF
SVKLKIISAFGYNGLDSLILPSFALGLGMAGSLARVLRTCILEVMSSDYILTARAKGLSNKVVVLKHVLKNAFLPVITLM
GMKTAYLLGGAVIIESIFGWPGIGSYFIDIINAKDYPAVSGLVFIFGILFVLVNLIVDISYAILDPRVRYDKGV

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=37.0967741935484, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1789888, Length=313, Percent_Identity=38.3386581469649, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1789965, Length=343, Percent_Identity=33.5276967930029, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1787497, Length=313, Percent_Identity=35.7827476038339, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787761, Length=339, Percent_Identity=33.6283185840708, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1787550, Length=334, Percent_Identity=28.4431137724551, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=26.8493150684932, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34534; Mature: 34534

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFILRRLFLAIPMAIAVSLISFSLLYFSPGNPAEIILEQKSPDSSPDENAIKEYEKKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHC
GLDKPFYDLYVIWLSKALTGDFGVSLQNGEPVIDEFMARFPYTVMIMVGATTVYFVLGVV
CCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHH
MGILSALNKDGIIDNIVRAYASLKMAIPSFWLALLLIWVFSVKLKIISAFGYNGLDSLIL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PSFALGLGMAGSLARVLRTCILEVMSSDYILTARAKGLSNKVVVLKHVLKNAFLPVITLM
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GMKTAYLLGGAVIIESIFGWPGIGSYFIDIINAKDYPAVSGLVFIFGILFVLVNLIVDIS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YAILDPRVRYDKGV
HHHHCCCHHCCCCC
>Mature Secondary Structure
MKNFILRRLFLAIPMAIAVSLISFSLLYFSPGNPAEIILEQKSPDSSPDENAIKEYEKKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHC
GLDKPFYDLYVIWLSKALTGDFGVSLQNGEPVIDEFMARFPYTVMIMVGATTVYFVLGVV
CCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHH
MGILSALNKDGIIDNIVRAYASLKMAIPSFWLALLLIWVFSVKLKIISAFGYNGLDSLIL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PSFALGLGMAGSLARVLRTCILEVMSSDYILTARAKGLSNKVVVLKHVLKNAFLPVITLM
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GMKTAYLLGGAVIIESIFGWPGIGSYFIDIINAKDYPAVSGLVFIFGILFVLVNLIVDIS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YAILDPRVRYDKGV
HHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]