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The map label for this gene is wecB [H]

Identifier: 150400917

GI number: 150400917

Start: 508468

End: 509640

Strand: Direct

Name: wecB [H]

Synonym: Maeo_0485

Alternate gene names: 150400917

Gene position: 508468-509640 (Clockwise)

Preceding gene: 150400916

Following gene: 150400918

Centisome position: 32.4

GC content: 29.33

Gene sequence:

>1173_bases
ATGAAAATAGCAATAATATTAGGAACAAGGCCAGAAATTATTAAATTATCTTCAATTATTAGGGAGCTCCAAAATTTTTC
AAAGGAAAATTTTTACAGTTGTAAAACTTGTGAAGCAAATCTAAAACACAATCAATCAAACACCCATAAGGATAATAAAA
ACATTGAATATTTTATAATACATACAAATCAACATTATTCTAAAAATATGGACGAAATATTTTTTAAAGAATTAAATCTG
CCAACTCCGAAATACAATTTAAATGTTGGTTCTGGGACACATGGCGAACAAACCGCAAAAATGATTGACGGTATTGAAAA
AATATTAATATCGGAAAATCCCGATGTAGTAATTGTTCAAGGGGATACAAACACAGTTCTTGCAGGAGCTCTATCAGCTT
CAAAATTACATATAAAGGTAGCACATGTTGAAGCAGGATTGCGAAGTTATGACCGAAATATGCCGGAAGAAACAAACAGG
GTTTTAACAGACCATATTAGTAACTACCTATTTGCACCAACTGAAATAGCAAAACATAATTTATTGAAAGAGGGAATTAA
TAAAAATGTGTTTGTCGTCGGAAATACTATTGTAGATGCCACAATTCAAAATATAGAAATTGCCGAAAATATATATAAAT
ATAATAATATGTCCATAAAAACCAATATAAATGAAGATTATTTTTTATTAACACTCCATAGGGCAGAAAATACGGACAAT
AAAGAAAGATTAACAAATATTGTTAATGCCATTATCAAAGCAACGGAGCAATATAATAAAAAAATCATATTTCCAATGCA
CCCCAGAACGGAGAAAAAATTAAAAGAATATAATTTATTTGAAAATTTACAAAAAAACAGTAAAATAGAAATTATAGAAC
CAGTGGGCTATTTAGAATTTCTACTTCTTGAAAAAAATGCAAAATTAATATTAACGGATAGTGGGGGAGTTCAAGAAGAG
GCCTGTATTTTGGGAGCTCCATGTATAACATTGAGAGATAATACCGAAAGACCAGAAACTATATATATTGGAAGTAATAT
ATTGGTAAATGCCGATATAAATAAAATTTTAGATGGTATCGGCGTAATGGCCAATAAAAAAATAAATGGGAATAATCCTT
TTGGAGATGGAAATAGTGGCAAAGCCATCGTTAAAATATTGCTGGAAAATTAA

Upstream 100 bases:

>100_bases
GCGATTTTTACGACCTCAAAATTCCAGAGGAATTTTTACGATAGGGCAAATAAGAGACAGTTATTGAAGATTAATTATAA
ATTATGTTGGGTGTAGGTAA

Downstream 100 bases:

>100_bases
TATATGGTTAATTTAAAAAGCCCATGTATTAATTAATCTATTGTTAATAGCAAAATATTTAACTATGGTTAAATTTATTA
AGTTATATAAAATATGTGAA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKIAIILGTRPEIIKLSSIIRELQNFSKENFYSCKTCEANLKHNQSNTHKDNKNIEYFIIHTNQHYSKNMDEIFFKELNL
PTPKYNLNVGSGTHGEQTAKMIDGIEKILISENPDVVIVQGDTNTVLAGALSASKLHIKVAHVEAGLRSYDRNMPEETNR
VLTDHISNYLFAPTEIAKHNLLKEGINKNVFVVGNTIVDATIQNIEIAENIYKYNNMSIKTNINEDYFLLTLHRAENTDN
KERLTNIVNAIIKATEQYNKKIIFPMHPRTEKKLKEYNLFENLQKNSKIEIIEPVGYLEFLLLEKNAKLILTDSGGVQEE
ACILGAPCITLRDNTERPETIYIGSNILVNADINKILDGIGVMANKKINGNNPFGDGNSGKAIVKILLEN

Sequences:

>Translated_390_residues
MKIAIILGTRPEIIKLSSIIRELQNFSKENFYSCKTCEANLKHNQSNTHKDNKNIEYFIIHTNQHYSKNMDEIFFKELNL
PTPKYNLNVGSGTHGEQTAKMIDGIEKILISENPDVVIVQGDTNTVLAGALSASKLHIKVAHVEAGLRSYDRNMPEETNR
VLTDHISNYLFAPTEIAKHNLLKEGINKNVFVVGNTIVDATIQNIEIAENIYKYNNMSIKTNINEDYFLLTLHRAENTDN
KERLTNIVNAIIKATEQYNKKIIFPMHPRTEKKLKEYNLFENLQKNSKIEIIEPVGYLEFLLLEKNAKLILTDSGGVQEE
ACILGAPCITLRDNTERPETIYIGSNILVNADINKILDGIGVMANKKINGNNPFGDGNSGKAIVKILLEN
>Mature_390_residues
MKIAIILGTRPEIIKLSSIIRELQNFSKENFYSCKTCEANLKHNQSNTHKDNKNIEYFIIHTNQHYSKNMDEIFFKELNL
PTPKYNLNVGSGTHGEQTAKMIDGIEKILISENPDVVIVQGDTNTVLAGALSASKLHIKVAHVEAGLRSYDRNMPEETNR
VLTDHISNYLFAPTEIAKHNLLKEGINKNVFVVGNTIVDATIQNIEIAENIYKYNNMSIKTNINEDYFLLTLHRAENTDN
KERLTNIVNAIIKATEQYNKKIIFPMHPRTEKKLKEYNLFENLQKNSKIEIIEPVGYLEFLLLEKNAKLILTDSGGVQEE
ACILGAPCITLRDNTERPETIYIGSNILVNADINKILDGIGVMANKKINGNNPFGDGNSGKAIVKILLEN

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=411, Percent_Identity=32.1167883211679, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44009; Mature: 44009

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIILGTRPEIIKLSSIIRELQNFSKENFYSCKTCEANLKHNQSNTHKDNKNIEYFII
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEE
HTNQHYSKNMDEIFFKELNLPTPKYNLNVGSGTHGEQTAKMIDGIEKILISENPDVVIVQ
ECCCCHHCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GDTNTVLAGALSASKLHIKVAHVEAGLRSYDRNMPEETNRVLTDHISNYLFAPTEIAKHN
CCCCEEEEEECCCCEEEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCEECCHHHHHHH
LLKEGINKNVFVVGNTIVDATIQNIEIAENIYKYNNMSIKTNINEDYFLLTLHRAENTDN
HHHHCCCCCEEEEECEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCCH
KERLTNIVNAIIKATEQYNKKIIFPMHPRTEKKLKEYNLFENLQKNSKIEIIEPVGYLEF
HHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEE
LLLEKNAKLILTDSGGVQEEACILGAPCITLRDNTERPETIYIGSNILVNADINKILDGI
EEEECCCEEEEECCCCCCCCCEEECCCEEEECCCCCCCCEEEECCEEEEECCHHHHHHHH
GVMANKKINGNNPFGDGNSGKAIVKILLEN
CCEECCEECCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKIAIILGTRPEIIKLSSIIRELQNFSKENFYSCKTCEANLKHNQSNTHKDNKNIEYFII
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEE
HTNQHYSKNMDEIFFKELNLPTPKYNLNVGSGTHGEQTAKMIDGIEKILISENPDVVIVQ
ECCCCHHCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GDTNTVLAGALSASKLHIKVAHVEAGLRSYDRNMPEETNRVLTDHISNYLFAPTEIAKHN
CCCCEEEEEECCCCEEEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCEECCHHHHHHH
LLKEGINKNVFVVGNTIVDATIQNIEIAENIYKYNNMSIKTNINEDYFLLTLHRAENTDN
HHHHCCCCCEEEEECEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCCH
KERLTNIVNAIIKATEQYNKKIIFPMHPRTEKKLKEYNLFENLQKNSKIEIIEPVGYLEF
HHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEE
LLLEKNAKLILTDSGGVQEEACILGAPCITLRDNTERPETIYIGSNILVNADINKILDGI
EEEECCCEEEEECCCCCCCCCEEECCCEEEECCCCCCCCEEEECCEEEEECCHHHHHHHH
GVMANKKINGNNPFGDGNSGKAIVKILLEN
CCEECCEECCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]