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The map label for this gene is kch [C]

Identifier: 150400883

GI number: 150400883

Start: 473749

End: 474759

Strand: Direct

Name: kch [C]

Synonym: Maeo_0451

Alternate gene names: 150400883

Gene position: 473749-474759 (Clockwise)

Preceding gene: 150400879

Following gene: 150400884

Centisome position: 30.18

GC content: 31.75

Gene sequence:

>1011_bases
ATGGAAGCAATAAAACAAATAAAAATTGGAATTACTGTTATAGGAGTTATTATATTGTTGGCATCATTAGGTTTAATGAG
GTATGAAAATTGGGATTTTTTCACTGCTCTATATGTAACAATAATCACAATTACCACGGTTGGATATGGTGATTATGTCC
CCCAAACAATTAAAGGAAAACTTATCACGGTTGGATATATAATATTTGGAGCAGGTGCCATGGCATATACTTTTGGGTCT
ATTGCAGGGTTTTTTATTGAGGGACGATTTAAAGAAATAATATACTTAAAAAAAATGAAGTCAAGGTTAAAAAAAATGGA
AGATCATTATATTATTTGTGGATTTGGTAAAATTGGTAAGGTAGTAGCTAAAAAATTTGAAGATGCAAATGTGCCTTATG
TAGTAATTGATTCCGACCAATCAATAATGGAGAGTCCATTAGAGCAATATCCTCATTTATCATATGTAATTGGAGATGCT
TCCTCGGATGAGATATTAATAAAAGCAGGTGCGCATAAGGCTAAGGGATTAATAACCGCAGTAAATTCCGATGCAGATAA
TGCCTTTATCACCATATCTGCAAAAGAGATAAATCCAAACATATATATTGTTGCAAAAGCTGATAAAGATAGCTCTGTTG
ATAAATTAATAAAAGCAGGTGCGGATAGGGCAGTATCTCCATATGACATAGGAGGATTGAGAATCGCAGAACTGTCCCTA
AAACCTGAAATTCTTGATTTTGTATCTACTCTTATGGATGCATCACAAGATATGGAAATTGGAAGATATGAAGTATCTCC
AAATTCAAAGGTTGTTGGACATTCTCTTTATGAGTGCAAAATAAGACAAACAACTGGAACTACAATTCTTGCCATTAAAA
AAATTAAAGAAGATGGCAGTGATGATATTATTATTAATCCAGAGTCCGATGTGATTTTAAAAGAGCATGACATATTATAT
GTATTTGGAACAAAAGAACAATTAAGAAAACTTAAAGAAATATTATTATAA

Upstream 100 bases:

>100_bases
TATACGATATACACACATAAAGAATAAAATCATTATTGTTATATAATTTATTTTTATATTTTATTATATTTTTATTCTTT
ATATTTATTTATGTGATTAA

Downstream 100 bases:

>100_bases
AATGAAGATAGTATTTAATAATATATATTATTTAAAATAAAAATATAGAGGAGATATAATGAATAATATAGAATCTACTG
AATATATTGAATTAAAAGGA

Product: TrkA domain-containing protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK1 [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MEAIKQIKIGITVIGVIILLASLGLMRYENWDFFTALYVTIITITTVGYGDYVPQTIKGKLITVGYIIFGAGAMAYTFGS
IAGFFIEGRFKEIIYLKKMKSRLKKMEDHYIICGFGKIGKVVAKKFEDANVPYVVIDSDQSIMESPLEQYPHLSYVIGDA
SSDEILIKAGAHKAKGLITAVNSDADNAFITISAKEINPNIYIVAKADKDSSVDKLIKAGADRAVSPYDIGGLRIAELSL
KPEILDFVSTLMDASQDMEIGRYEVSPNSKVVGHSLYECKIRQTTGTTILAIKKIKEDGSDDIIINPESDVILKEHDILY
VFGTKEQLRKLKEILL

Sequences:

>Translated_336_residues
MEAIKQIKIGITVIGVIILLASLGLMRYENWDFFTALYVTIITITTVGYGDYVPQTIKGKLITVGYIIFGAGAMAYTFGS
IAGFFIEGRFKEIIYLKKMKSRLKKMEDHYIICGFGKIGKVVAKKFEDANVPYVVIDSDQSIMESPLEQYPHLSYVIGDA
SSDEILIKAGAHKAKGLITAVNSDADNAFITISAKEINPNIYIVAKADKDSSVDKLIKAGADRAVSPYDIGGLRIAELSL
KPEILDFVSTLMDASQDMEIGRYEVSPNSKVVGHSLYECKIRQTTGTTILAIKKIKEDGSDDIIINPESDVILKEHDILY
VFGTKEQLRKLKEILL
>Mature_336_residues
MEAIKQIKIGITVIGVIILLASLGLMRYENWDFFTALYVTIITITTVGYGDYVPQTIKGKLITVGYIIFGAGAMAYTFGS
IAGFFIEGRFKEIIYLKKMKSRLKKMEDHYIICGFGKIGKVVAKKFEDANVPYVVIDSDQSIMESPLEQYPHLSYVIGDA
SSDEILIKAGAHKAKGLITAVNSDADNAFITISAKEINPNIYIVAKADKDSSVDKLIKAGADRAVSPYDIGGLRIAELSL
KPEILDFVSTLMDASQDMEIGRYEVSPNSKVVGHSLYECKIRQTTGTTILAIKKIKEDGSDDIIINPESDVILKEHDILY
VFGTKEQLRKLKEILL

Specific function: Potassium channel protein. Seems to conduct potassium at low membrane potentials [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=226, Percent_Identity=27.4336283185841, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786685, Length=118, Percent_Identity=28.8135593220339, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003280
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 37124; Mature: 37124

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIKQIKIGITVIGVIILLASLGLMRYENWDFFTALYVTIITITTVGYGDYVPQTIKGK
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHEECCCCCCCCHHHCCC
LITVGYIIFGAGAMAYTFGSIAGFFIEGRFKEIIYLKKMKSRLKKMEDHYIICGFGKIGK
EEEEEEHHHCCCHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
VVAKKFEDANVPYVVIDSDQSIMESPLEQYPHLSYVIGDASSDEILIKAGAHKAKGLITA
HHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEE
VNSDADNAFITISAKEINPNIYIVAKADKDSSVDKLIKAGADRAVSPYDIGGLRIAELSL
ECCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
KPEILDFVSTLMDASQDMEIGRYEVSPNSKVVGHSLYECKIRQTTGTTILAIKKIKEDGS
CHHHHHHHHHHHCCCCCCCCCEEEECCCCCEECCCEEEEEEEECCCCEEEEEEEHHCCCC
DDIIINPESDVILKEHDILYVFGTKEQLRKLKEILL
CCEEECCCCCEEEEECCEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure
MEAIKQIKIGITVIGVIILLASLGLMRYENWDFFTALYVTIITITTVGYGDYVPQTIKGK
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHEECCCCCCCCHHHCCC
LITVGYIIFGAGAMAYTFGSIAGFFIEGRFKEIIYLKKMKSRLKKMEDHYIICGFGKIGK
EEEEEEHHHCCCHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
VVAKKFEDANVPYVVIDSDQSIMESPLEQYPHLSYVIGDASSDEILIKAGAHKAKGLITA
HHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEE
VNSDADNAFITISAKEINPNIYIVAKADKDSSVDKLIKAGADRAVSPYDIGGLRIAELSL
ECCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
KPEILDFVSTLMDASQDMEIGRYEVSPNSKVVGHSLYECKIRQTTGTTILAIKKIKEDGS
CHHHHHHHHHHHCCCCCCCCCEEEECCCCCEECCCEEEEEEEECCCCEEEEEEEHHCCCC
DDIIINPESDVILKEHDILYVFGTKEQLRKLKEILL
CCEEECCCCCEEEEECCEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]