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The map label for this gene is mch

Identifier: 150400873

GI number: 150400873

Start: 461420

End: 462394

Strand: Reverse

Name: mch

Synonym: Maeo_0441

Alternate gene names: 150400873

Gene position: 462394-461420 (Counterclockwise)

Preceding gene: 150400876

Following gene: 150400871

Centisome position: 29.46

GC content: 34.87

Gene sequence:

>975_bases
ATGTTAAGTGTAAATTTAAAATCTTTGCCAATTGTAGAAAATATGATTGAAAAAGCGGAAGAAATGAACATTGAAGTAAT
AAAATTAGAAAATGGGGCAACAGTTTTAGATTGTGGAGTAAATGTTATGGGAAGTATAGAGGCAGGAAAAGCCTTTACAA
AAATATGTTTAGGAGGATTAGCTCATGTTGGAGTTAGTATAGCTGGAACCGTATCCGATGAGATGGTATTACCTTGTGTA
AAAGTTAAAACCTCACATCCTGCAATAGCAACATTGGGATCCCAAAAAGCAGGTTGGACAATTAACATTGGAAAATTCTT
TGCTATGGGTTCAGGACCTGCGAGAGCATTGGCAAAGATACCAAAAGCAACCTACGAAGAAATAAACTACGAAGACAACG
CAGATGTTGCTATTTTATGTTTGGAAGCATCACAATTACCAAATGAAGAAGTTGCAGAATTTGTTGCTGAAAAATGTGGT
GTAGATGTAAGTAAAGTATATCTTTTAGTAGCTCCAACCTCATCACTTGTAGGGTCAATACAAATAAGTGGTAGAGTTGT
AGAAAACGGAACCTATAAAATGCTTGAAGCTCTCCACTTCGATGTTAATAAAGTTAAATTTGCAGCTGGAATCGCACCTG
TTGCTCCAATTATTGGAGACGATTTGGCTATGATGGGAGCTACAAATGATATGGTATTATATGGAGGTAGAACATACTAC
TACATAGAAAGTGATGAAAATGATGATGTAGAAGCACTTTGTAAAGCACTTCCTTCATGCTCATCACAAGATTACGGTAA
GCCATTTTTAGAAACATTTAAAGCAGCAAACTACGACTTCTATAAAATAGATAAAGGAATGTTTGCTCCTGCTGTTGTTG
TAATAAATGATATGAGAACAGGAAAATTGGTAACTTATGGAAAGCCACATGTAGATGTTCTTAAAAAATCATTAGGATAC
AAAGAATTAGAATAA

Upstream 100 bases:

>100_bases
GCTTTGCGATTTTGAGACAGTTTATTGAAAAAGACCGAAGATTTACTATAAATACATACTCTATATATTATATATCCAAT
AACATAAAACTGGTGAAAAA

Downstream 100 bases:

>100_bases
TTAAAAATTATTATTTATTTTATGGGAGCTCCTTGGAGCTCCCTATTTTATAAATTAGATTATTACTTATTCATTTTTCT
CCATATATTTATCTATCAAT

Product: N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase

Products: NA

Alternate protein names: Methenyl-H4MPT cyclohydrolase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLSVNLKSLPIVENMIEKAEEMNIEVIKLENGATVLDCGVNVMGSIEAGKAFTKICLGGLAHVGVSIAGTVSDEMVLPCV
KVKTSHPAIATLGSQKAGWTINIGKFFAMGSGPARALAKIPKATYEEINYEDNADVAILCLEASQLPNEEVAEFVAEKCG
VDVSKVYLLVAPTSSLVGSIQISGRVVENGTYKMLEALHFDVNKVKFAAGIAPVAPIIGDDLAMMGATNDMVLYGGRTYY
YIESDENDDVEALCKALPSCSSQDYGKPFLETFKAANYDFYKIDKGMFAPAVVVINDMRTGKLVTYGKPHVDVLKKSLGY
KELE

Sequences:

>Translated_324_residues
MLSVNLKSLPIVENMIEKAEEMNIEVIKLENGATVLDCGVNVMGSIEAGKAFTKICLGGLAHVGVSIAGTVSDEMVLPCV
KVKTSHPAIATLGSQKAGWTINIGKFFAMGSGPARALAKIPKATYEEINYEDNADVAILCLEASQLPNEEVAEFVAEKCG
VDVSKVYLLVAPTSSLVGSIQISGRVVENGTYKMLEALHFDVNKVKFAAGIAPVAPIIGDDLAMMGATNDMVLYGGRTYY
YIESDENDDVEALCKALPSCSSQDYGKPFLETFKAANYDFYKIDKGMFAPAVVVINDMRTGKLVTYGKPHVDVLKKSLGY
KELE
>Mature_324_residues
MLSVNLKSLPIVENMIEKAEEMNIEVIKLENGATVLDCGVNVMGSIEAGKAFTKICLGGLAHVGVSIAGTVSDEMVLPCV
KVKTSHPAIATLGSQKAGWTINIGKFFAMGSGPARALAKIPKATYEEINYEDNADVAILCLEASQLPNEEVAEFVAEKCG
VDVSKVYLLVAPTSSLVGSIQISGRVVENGTYKMLEALHFDVNKVKFAAGIAPVAPIIGDDLAMMGATNDMVLYGGRTYY
YIESDENDDVEALCKALPSCSSQDYGKPFLETFKAANYDFYKIDKGMFAPAVVVINDMRTGKLVTYGKPHVDVLKKSLGY
KELE

Specific function: Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT(+)

COG id: COG3252

COG function: function code H; Methenyltetrahydromethanopterin cyclohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MCH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MCH_META3 (A6UU55)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324639.1
- ProteinModelPortal:   A6UU55
- SMR:   A6UU55
- STRING:   A6UU55
- GeneID:   5327209
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0441
- eggNOG:   arNOG05033
- HOGENOM:   HBG497176
- OMA:   YFAMGSG
- ProtClustDB:   PRK02264
- BioCyc:   MAEO419665:MAEO_0441-MONOMER
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_00486
- InterPro:   IPR003209
- TIGRFAMs:   TIGR03120

Pfam domain/function: PF02289 MCH; SSF56199 Cyclohydrolase

EC number: =3.5.4.27

Molecular weight: Translated: 34801; Mature: 34801

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVNLKSLPIVENMIEKAEEMNIEVIKLENGATVLDCGVNVMGSIEAGKAFTKICLGGL
CEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEECCCHHHHHHHHHHHHH
AHVGVSIAGTVSDEMVLPCVKVKTSHPAIATLGSQKAGWTINIGKFFAMGSGPARALAKI
HHHCEEEEECCCCCEEEEEEEEECCCCCEEECCCCCCCEEEECCCEEEECCCHHHHHHHC
PKATYEEINYEDNADVAILCLEASQLPNEEVAEFVAEKCGVDVSKVYLLVAPTSSLVGSI
CCHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHEEEEEECCHHHEEEE
QISGRVVENGTYKMLEALHFDVNKVKFAAGIAPVAPIIGDDLAMMGATNDMVLYGGRTYY
EEEEEEEECCHHHHHHHHHCCHHHEEEHHCCCCHHHHHCCCEEEECCCCCEEEECCEEEE
YIESDENDDVEALCKALPSCSSQDYGKPFLETFKAANYDFYKIDKGMFAPAVVVINDMRT
EEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
GKLVTYGKPHVDVLKKSLGYKELE
CEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSVNLKSLPIVENMIEKAEEMNIEVIKLENGATVLDCGVNVMGSIEAGKAFTKICLGGL
CEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEECCCHHHHHHHHHHHHH
AHVGVSIAGTVSDEMVLPCVKVKTSHPAIATLGSQKAGWTINIGKFFAMGSGPARALAKI
HHHCEEEEECCCCCEEEEEEEEECCCCCEEECCCCCCCEEEECCCEEEECCCHHHHHHHC
PKATYEEINYEDNADVAILCLEASQLPNEEVAEFVAEKCGVDVSKVYLLVAPTSSLVGSI
CCHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHEEEEEECCHHHEEEE
QISGRVVENGTYKMLEALHFDVNKVKFAAGIAPVAPIIGDDLAMMGATNDMVLYGGRTYY
EEEEEEEECCHHHHHHHHHCCHHHEEEHHCCCCHHHHHCCCEEEECCCCCEEEECCEEEE
YIESDENDDVEALCKALPSCSSQDYGKPFLETFKAANYDFYKIDKGMFAPAVVVINDMRT
EEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
GKLVTYGKPHVDVLKKSLGYKELE
CEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA