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The map label for this gene is cobB [H]

Identifier: 150400743

GI number: 150400743

Start: 333840

End: 335210

Strand: Direct

Name: cobB [H]

Synonym: Maeo_0309

Alternate gene names: 150400743

Gene position: 333840-335210 (Clockwise)

Preceding gene: 150400742

Following gene: 150400744

Centisome position: 21.27

GC content: 31.07

Gene sequence:

>1371_bases
ATGGATTTTAAAAGAATAATTTTAGCAGGGACTTCTTCAATGGTTGGAAAGACCACAATATCCACGGGGATAATGAAAGC
ACTTTCAAAAAAATATACAATTCAACCCTATAAAATAGGACCAGATTACATTGACCCAACATACCATACAACAGCCACTA
AAAACCAAAGTCGGAATTTGGACTCTTTTTTTATGGACGATGGCCAAATAATGGAGTTATTTAAAAGAAATTCTAAAAAT
AGCAATGCCGATATAAGTGTTATAGAGGGTGTTAGGGGACTATATGAAGGTATTTCCCCATATAATGATATAGGAACTAC
GGCCTCAATCTCTAAATCATTAAATGCTTCCACAATATTGATAGTTGATGGAAGAAGCCTAACACGAAGTGCCGCAGCAA
TTATAAAAGGGTTTAAAAGCTTTGACACAGATGTAAATATTGATGGAGTAATATTTAATAAAATTAGGGGGGAAAAACAT
TATAAAAAATTAAAAGAAGCTATAAATTATTATGTTCCAGATATAGAAGTTATCGGAGCTCTACCGCGAGATGAAAAACT
TGAAGTATCTCAAAGACATTTGGGGCTTGTTCCAACCCCAGAAAATAGGGAAAAACTTAATAATGATGTGGAGCTTTGGG
GAAAAGTTGTTGAAGAACATCTTGATTTAGATAAAATAGTTGAATTAAGTAATAGATATGAATTAGAGGAGGCAGAGGCA
AATAATACAATAAATACAACAGAACATACCAAATTATATGAATTAAATAAAAATAAATGCACAGTAGGGGTTGCATATGA
TGAAGTTTTTAATTTCTACTATTGGGATAATTTTAAAGCATTAGAGGATAATGGGGCAAAAATAAAGTTTTTTAGTCCTT
TGAATGATGAATATATTCCAGATTGCGATGTGTTGTATTTGGGCGGAGGATATCCTGAAATTTATGCCAATGAATTAAAT
AAAAATAAATCTATGATGGAAAGTATTAAAAATTTTGATGGAAAAATATATGGCGAATGTGGAGGTTTAATGTATTTAAC
TAATTCAATAAATGGCATTAAAATGACGGGGGTTTTGGACTGTGATTCAATTATGACAGATAGAGTGCAGGGGTTAAGTT
ATGTTAAAGCAACTTTTATGTCGGATTGTATGGTAGGTAAAAAAGGAGCGGAATTTAAAGCACATGAATTCCACTATTCA
AAATTAATAAATATAAAAGAAAAATCATTTGCATATGATATAAATAGAGGAACAGGGATAATAAATAATAAAGATGGCAT
AATTAAAGACAATAGGATATTGGGCGGATATGCACATCAACATTGTGTAGCAAATCCTTATTTTGCATGTTCTTTGGTAA
ATAATATTTAA

Upstream 100 bases:

>100_bases
GTTATTACGATATCGGAAATTATTAATATTATTATATCGCAGTTATTGTTATTATTAAAATATGTATAAAATTTAAAAAA
TTAAATTTAAAGTGATATAT

Downstream 100 bases:

>100_bases
TAATTAAAAAAATAATGTAAAGAAATTATAATGTAAATATAAATATAAAAAATGGGAAAATATGTGGTCTAAATCGATTT
TAAAACATGGGTATGAATTG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDFKRIILAGTSSMVGKTTISTGIMKALSKKYTIQPYKIGPDYIDPTYHTTATKNQSRNLDSFFMDDGQIMELFKRNSKN
SNADISVIEGVRGLYEGISPYNDIGTTASISKSLNASTILIVDGRSLTRSAAAIIKGFKSFDTDVNIDGVIFNKIRGEKH
YKKLKEAINYYVPDIEVIGALPRDEKLEVSQRHLGLVPTPENREKLNNDVELWGKVVEEHLDLDKIVELSNRYELEEAEA
NNTINTTEHTKLYELNKNKCTVGVAYDEVFNFYYWDNFKALEDNGAKIKFFSPLNDEYIPDCDVLYLGGGYPEIYANELN
KNKSMMESIKNFDGKIYGECGGLMYLTNSINGIKMTGVLDCDSIMTDRVQGLSYVKATFMSDCMVGKKGAEFKAHEFHYS
KLINIKEKSFAYDINRGTGIINNKDGIIKDNRILGGYAHQHCVANPYFACSLVNNI

Sequences:

>Translated_456_residues
MDFKRIILAGTSSMVGKTTISTGIMKALSKKYTIQPYKIGPDYIDPTYHTTATKNQSRNLDSFFMDDGQIMELFKRNSKN
SNADISVIEGVRGLYEGISPYNDIGTTASISKSLNASTILIVDGRSLTRSAAAIIKGFKSFDTDVNIDGVIFNKIRGEKH
YKKLKEAINYYVPDIEVIGALPRDEKLEVSQRHLGLVPTPENREKLNNDVELWGKVVEEHLDLDKIVELSNRYELEEAEA
NNTINTTEHTKLYELNKNKCTVGVAYDEVFNFYYWDNFKALEDNGAKIKFFSPLNDEYIPDCDVLYLGGGYPEIYANELN
KNKSMMESIKNFDGKIYGECGGLMYLTNSINGIKMTGVLDCDSIMTDRVQGLSYVKATFMSDCMVGKKGAEFKAHEFHYS
KLINIKEKSFAYDINRGTGIINNKDGIIKDNRILGGYAHQHCVANPYFACSLVNNI
>Mature_456_residues
MDFKRIILAGTSSMVGKTTISTGIMKALSKKYTIQPYKIGPDYIDPTYHTTATKNQSRNLDSFFMDDGQIMELFKRNSKN
SNADISVIEGVRGLYEGISPYNDIGTTASISKSLNASTILIVDGRSLTRSAAAIIKGFKSFDTDVNIDGVIFNKIRGEKH
YKKLKEAINYYVPDIEVIGALPRDEKLEVSQRHLGLVPTPENREKLNNDVELWGKVVEEHLDLDKIVELSNRYELEEAEA
NNTINTTEHTKLYELNKNKCTVGVAYDEVFNFYYWDNFKALEDNGAKIKFFSPLNDEYIPDCDVLYLGGGYPEIYANELN
KNKSMMESIKNFDGKIYGECGGLMYLTNSINGIKMTGVLDCDSIMTDRVQGLSYVKATFMSDCMVGKKGAEFKAHEFHYS
KLINIKEKSFAYDINRGTGIINNKDGIIKDNRILGGYAHQHCVANPYFACSLVNNI

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 51311; Mature: 51311

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKRIILAGTSSMVGKTTISTGIMKALSKKYTIQPYKIGPDYIDPTYHTTATKNQSRNL
CCCCEEEEECCCCHHCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
DSFFMDDGQIMELFKRNSKNSNADISVIEGVRGLYEGISPYNDIGTTASISKSLNASTIL
HHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCHHHHHCCCCCEEE
IVDGRSLTRSAAAIIKGFKSFDTDVNIDGVIFNKIRGEKHYKKLKEAINYYVPDIEVIGA
EECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHCCCCCCEEEC
LPRDEKLEVSQRHLGLVPTPENREKLNNDVELWGKVVEEHLDLDKIVELSNRYELEEAEA
CCCCCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHC
NNTINTTEHTKLYELNKNKCTVGVAYDEVFNFYYWDNFKALEDNGAKIKFFSPLNDEYIP
CCCCCCCCCCEEEEECCCEEEEEEEHHHHHEEEEECCEEEECCCCCEEEEECCCCCCCCC
DCDVLYLGGGYPEIYANELNKNKSMMESIKNFDGKIYGECGGLMYLTNSINGIKMTGVLD
CCCEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEEEC
CDSIMTDRVQGLSYVKATFMSDCMVGKKGAEFKAHEFHYSKLINIKEKSFAYDINRGTGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCE
INNKDGIIKDNRILGGYAHQHCVANPYFACSLVNNI
EECCCCEEECCEEECCHHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure
MDFKRIILAGTSSMVGKTTISTGIMKALSKKYTIQPYKIGPDYIDPTYHTTATKNQSRNL
CCCCEEEEECCCCHHCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
DSFFMDDGQIMELFKRNSKNSNADISVIEGVRGLYEGISPYNDIGTTASISKSLNASTIL
HHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCHHHHHCCCCCEEE
IVDGRSLTRSAAAIIKGFKSFDTDVNIDGVIFNKIRGEKHYKKLKEAINYYVPDIEVIGA
EECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHCCCCCCEEEC
LPRDEKLEVSQRHLGLVPTPENREKLNNDVELWGKVVEEHLDLDKIVELSNRYELEEAEA
CCCCCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHC
NNTINTTEHTKLYELNKNKCTVGVAYDEVFNFYYWDNFKALEDNGAKIKFFSPLNDEYIP
CCCCCCCCCCEEEEECCCEEEEEEEHHHHHEEEEECCEEEECCCCCEEEEECCCCCCCCC
DCDVLYLGGGYPEIYANELNKNKSMMESIKNFDGKIYGECGGLMYLTNSINGIKMTGVLD
CCCEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEEEC
CDSIMTDRVQGLSYVKATFMSDCMVGKKGAEFKAHEFHYSKLINIKEKSFAYDINRGTGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCE
INNKDGIIKDNRILGGYAHQHCVANPYFACSLVNNI
EECCCCEEECCEEECCHHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA