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The map label for this gene is kamA [H]

Identifier: 150400676

GI number: 150400676

Start: 265656

End: 266969

Strand: Direct

Name: kamA [H]

Synonym: Maeo_0240

Alternate gene names: 150400676

Gene position: 265656-266969 (Clockwise)

Preceding gene: 150400675

Following gene: 150400677

Centisome position: 16.93

GC content: 36.99

Gene sequence:

>1314_bases
ATGGAGAAAATATTTGATAAGAAACATAAAGATTTTGCAGAAAAGATATCAAAAAATATAGGCTTGGAAGAATGGTATGA
CTGGAAATGGCAGTTGAAAAACTCCATAAGGGATATAGACACTTTTGAAGAAGTTATAGGCATAAAATTCCATGAAGACG
AAAAAGCAGAATTGCAGGAAGCAGCAGATGTATTTCCACTGTCAATAACGCCATATTATGCATCATTGATAGATGTAAAA
AACTTCAGAGAAGACCCTATTTTTAAGCAGTCTTTTGTTGGCGTAGAAGAATTAATAACCGAGAACTTTGAGATGGCTGA
CCCATTGGCTGAAGATAAAGATTCTCCGGTTCCAGGATTAACACATCGTTATCCAGATAGAATATTATTTTATATCAGTC
ATGCCTGTGCGGTATATTGTCGTCATTGCACCCGTAAAAGGAAAGTAGGCGATACAGATAGTATTCCGTCAAAAAAACAG
ATAGAAAAAGGACTGGATTATATTCGAAACAACCCTCAAATTAGGGATGTTCTTTTATCAGGGGGGGACCCACTACTTTT
GCCTGATGATTATTTAGACTGGATTTTAACTGAGTTGTGGAGTATACCACACATTGAAGTGATTAGAATAGGTACGAGAG
TTCCTGTGGTTTTACCTTATCGTATTACCGATGAATTAGTAAATATGCTGAAAAAGCACCATCCGCTATGGATAAATACT
CATTTTAATCATATAAAAGAAATAACAAAATCTTCAAAAAATGCATTAAGAAAACTGGCAGATGTTGGAATTCCTTTGGG
GAATCAGTCAGTATTATTGCGGGGGGTTAATGACTGTCCAAATGTCATTAAAAAACTTAATCAAAAATTGGCTGCAAATA
GGGTAAGACCATACTATCTTTTCCAGTGTGATTTATCGGAGGGGCTTTCACATTTTCGTACATCTGTGAGAAAAGGAGTT
GAAATTATAGAAAGTTTAATTGGCCATACAAGTGGATTTGCAGTTCCAAGGTATGTTGTAGATGCACCTGGCGGAGGAGG
TAAAATACCAGTCATGCCAAACTATGTAATTTCATGGGGGACTGACAGGGTTATTTTGAGAAATTATGAGGGCGTTATTA
CCACCTACAAGGAACCAGAGCACCAGGATGATTGCAGTAAAGATTGTACGGGCTGTGAAAGAGGGCTGGCAGAGGAAGGA
GAAGAGCATGATTTAGTTGGAATAGAGAAGTTACTCTTTAATTCGGCAGATGACACAATATCTCTAGTTCCACAAGGAAC
TGAAAGAATTGATAAAAGGGACAATAATGGATAA

Upstream 100 bases:

>100_bases
ATTTATTGCCACATATATTCTTTCCATAAAGAATAGTGTAATAGTGTAATTAGGCATCGACCTCCACATATTAATAAATA
ATAAACTAATGAGGTATATA

Downstream 100 bases:

>100_bases
AATAACAAATATCCATGGTTCAGTTATTCAGTTGAGTGATTTGAACGATAGAATATATTTGATGAAGTTGAATCAAGATA
AAATAGGGGAATTATTGCCA

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MEKIFDKKHKDFAEKISKNIGLEEWYDWKWQLKNSIRDIDTFEEVIGIKFHEDEKAELQEAADVFPLSITPYYASLIDVK
NFREDPIFKQSFVGVEELITENFEMADPLAEDKDSPVPGLTHRYPDRILFYISHACAVYCRHCTRKRKVGDTDSIPSKKQ
IEKGLDYIRNNPQIRDVLLSGGDPLLLPDDYLDWILTELWSIPHIEVIRIGTRVPVVLPYRITDELVNMLKKHHPLWINT
HFNHIKEITKSSKNALRKLADVGIPLGNQSVLLRGVNDCPNVIKKLNQKLAANRVRPYYLFQCDLSEGLSHFRTSVRKGV
EIIESLIGHTSGFAVPRYVVDAPGGGGKIPVMPNYVISWGTDRVILRNYEGVITTYKEPEHQDDCSKDCTGCERGLAEEG
EEHDLVGIEKLLFNSADDTISLVPQGTERIDKRDNNG

Sequences:

>Translated_437_residues
MEKIFDKKHKDFAEKISKNIGLEEWYDWKWQLKNSIRDIDTFEEVIGIKFHEDEKAELQEAADVFPLSITPYYASLIDVK
NFREDPIFKQSFVGVEELITENFEMADPLAEDKDSPVPGLTHRYPDRILFYISHACAVYCRHCTRKRKVGDTDSIPSKKQ
IEKGLDYIRNNPQIRDVLLSGGDPLLLPDDYLDWILTELWSIPHIEVIRIGTRVPVVLPYRITDELVNMLKKHHPLWINT
HFNHIKEITKSSKNALRKLADVGIPLGNQSVLLRGVNDCPNVIKKLNQKLAANRVRPYYLFQCDLSEGLSHFRTSVRKGV
EIIESLIGHTSGFAVPRYVVDAPGGGGKIPVMPNYVISWGTDRVILRNYEGVITTYKEPEHQDDCSKDCTGCERGLAEEG
EEHDLVGIEKLLFNSADDTISLVPQGTERIDKRDNNG
>Mature_437_residues
MEKIFDKKHKDFAEKISKNIGLEEWYDWKWQLKNSIRDIDTFEEVIGIKFHEDEKAELQEAADVFPLSITPYYASLIDVK
NFREDPIFKQSFVGVEELITENFEMADPLAEDKDSPVPGLTHRYPDRILFYISHACAVYCRHCTRKRKVGDTDSIPSKKQ
IEKGLDYIRNNPQIRDVLLSGGDPLLLPDDYLDWILTELWSIPHIEVIRIGTRVPVVLPYRITDELVNMLKKHHPLWINT
HFNHIKEITKSSKNALRKLADVGIPLGNQSVLLRGVNDCPNVIKKLNQKLAANRVRPYYLFQCDLSEGLSHFRTSVRKGV
EIIESLIGHTSGFAVPRYVVDAPGGGGKIPVMPNYVISWGTDRVILRNYEGVITTYKEPEHQDDCSKDCTGCERGLAEEG
EEHDLVGIEKLLFNSADDTISLVPQGTERIDKRDNNG

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=327, Percent_Identity=34.5565749235474, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 49954; Mature: 49954

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIFDKKHKDFAEKISKNIGLEEWYDWKWQLKNSIRDIDTFEEVIGIKFHEDEKAELQE
CCCHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AADVFPLSITPYYASLIDVKNFREDPIFKQSFVGVEELITENFEMADPLAEDKDSPVPGL
HHCCCCEEECHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCC
THRYPDRILFYISHACAVYCRHCTRKRKVGDTDSIPSKKQIEKGLDYIRNNPQIRDVLLS
CHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHC
GGDPLLLPDDYLDWILTELWSIPHIEVIRIGTRVPVVLPYRITDELVNMLKKHHPLWINT
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHCCCEEEEC
HFNHIKEITKSSKNALRKLADVGIPLGNQSVLLRGVNDCPNVIKKLNQKLAANRVRPYYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEE
FQCDLSEGLSHFRTSVRKGVEIIESLIGHTSGFAVPRYVVDAPGGGGKIPVMPNYVISWG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECC
TDRVILRNYEGVITTYKEPEHQDDCSKDCTGCERGLAEEGEEHDLVGIEKLLFNSADDTI
CCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCE
SLVPQGTERIDKRDNNG
EECCCCHHHHHCCCCCC
>Mature Secondary Structure
MEKIFDKKHKDFAEKISKNIGLEEWYDWKWQLKNSIRDIDTFEEVIGIKFHEDEKAELQE
CCCHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AADVFPLSITPYYASLIDVKNFREDPIFKQSFVGVEELITENFEMADPLAEDKDSPVPGL
HHCCCCEEECHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCC
THRYPDRILFYISHACAVYCRHCTRKRKVGDTDSIPSKKQIEKGLDYIRNNPQIRDVLLS
CHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHC
GGDPLLLPDDYLDWILTELWSIPHIEVIRIGTRVPVVLPYRITDELVNMLKKHHPLWINT
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHCCCEEEEC
HFNHIKEITKSSKNALRKLADVGIPLGNQSVLLRGVNDCPNVIKKLNQKLAANRVRPYYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEE
FQCDLSEGLSHFRTSVRKGVEIIESLIGHTSGFAVPRYVVDAPGGGGKIPVMPNYVISWG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECC
TDRVILRNYEGVITTYKEPEHQDDCSKDCTGCERGLAEEGEEHDLVGIEKLLFNSADDTI
CCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCE
SLVPQGTERIDKRDNNG
EECCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]