| Definition | Methanococcus aeolicus Nankai-3, complete genome. |
|---|---|
| Accession | NC_009635 |
| Length | 1,569,500 |
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The map label for this gene is rep [H]
Identifier: 150400668
GI number: 150400668
Start: 251709
End: 253964
Strand: Reverse
Name: rep [H]
Synonym: Maeo_0230
Alternate gene names: 150400668
Gene position: 253964-251709 (Counterclockwise)
Preceding gene: 150400669
Following gene: 150400667
Centisome position: 16.18
GC content: 28.63
Gene sequence:
>2256_bases TTGGGATATAAATTTAATGAGGAGCAAAAAAATAGTGTAAATCACAAAGATAATCCACTGTGGGTAGTAGCAGGTCCGGG CTCTGGTAAAACAGAAGTTCTGGTAGTTAGAACGCTAAAACTAATATTTGTAGATGGAGTTAATCCTAAATCAATAATCT TGACCACATTTACAAAAAAGGCATCACAAAATCTATTTGATAGAATTATAAAATATTCAACTAAATTATATGATTTATAT CCAGAATTAAAAGGGAGCTCCATAGAAATACACAGTTTAAGAGTTGGCACACTTCATAGTTTATGCAATGACATAATGAA GGAATACAAATATACAGACTACGAAAATTACAAACTAATAAATGAAATTGAAAATTATATATTTGTATATAATTACTGTC CCATTGCAAAATATGGAGCTAGATATAAAGAGATATGGACTAAATTTAGATGTTTAGTAGGTAGATATGATAAAGATTTA TGCTGTCAGATAATTGATTATAAAAACAAAGCTCGGCTAACCAGTGCAACCATCACTTTATTTAATAGAATTATCGAAGA TAAAGTTAATATTGATAAATTGAAAAATGGCAAAATATACCATAAAAAATTAGCCGAGGAATGCGAAAAATATTTGGAAA AATTAGAAGGATTTAAATTGTGCACATTTTCAACAATTCAATTAAAATTTATAGATTTTCTAAACTCAGAAGACGGCGAA TTGTTTTTAAGTGGCTCGGGATATAATCCACCAATAAAACATATTATGGTAGATGAATACCAAGATACAAATCCAATTCA AGAGGAAATATATTTCAAAATGGCAAAACAAATTGAAAATAATAATTTATGTGTTGTTGGCGATGATGACCAAGCTATGT ATAGGTTTAGGGGCGGAACAGTAGAATGTATGGTAAATTTTGATAAAACCTGTGTAGAAAAATTCAATATTCCCATAGAT AAAATTAATAAAATATTTTTAAAATCAAATTATCGTTCCCACCCAGATATTGTAAAATATTATGATGACTACATAAATTC ATATAAATATACAAAAGATGTGGAAATGGAACGAGCCAGAGTAAAGGATAAACCGCAATTAGTGGCAAAAAAAGAAATGG ATAAAGAAACAATTGACAATTATTTAGCTTTAAATTATATTGAAAAAGAAGACGATGAGAAATTAGCCGAAGAGGTTGCA AATACTATAAAATATTTTAAAGACAATGATATTATTGAGGATTACTCCCAATGCGTAATATTAATAAAAAGCACAAGGGA AATTGATTATAATGGCAATGATTCATTTATTGGGCATATTAGACAAAAATTATTGAATAATGGAATTGACATATATAATC CACGGTCAAAGAATTTTTTAAATCAAGAGGAAATAAAATTGGCGTTGGGGGCGTTTATATCTATTGTTGATACCGACATA AGCGTTTTAGAAAATAATTTAAGGTCTCAACCTATTAGCAACGAAGTTGTAAAATGGTATGAGGAATATCAAAACAATAA AAATAAATATCCAGAATTGAAAAAATATGTGGATAGTAGTGTAGAAAAACTAAAAACTATGGAAGAGGGCAGTTTTATTA ATTCTTCCATTGAAAATATACTTTATAAAATATATGCCTGTTATCCATTTACGGAATGGCTAAATGACGAGGAAAAAAGT TATAGGTTGGCAAAATTAACAAATTTATTTAATAGCTATTCTACAATACCCACGGAAAATTTAATAAGCAAAGGAAGTAT TTCAATTGATGGGCACACCAAAGGTAAAGTTGATGTAAAATGGTTAATAGAATTTTACGGCTCATTGGTGGGGCACTTTT TAGGGGGTATTGACGATATTGAGGACGAGGAAATAACTATTCCAGAAGGAAAAGTTCCTATAATGACGGTGCATCAGGCA AAAGGTTTAGAATTTCCGTTTGTGTTTGTATATCTCCAAAAATGGCAGAATAAAGCAAATGACGGGGCAATATTAGAACG AGAATTTGCAGAATTTACGGATTTTAAGAGAATATCCACAATACCACGAAAAAAAACATTTCAAGATATTATTAGATTTC ATTATGTGGCATACTCTCGGGCTCAATATGGGCTTATACATTTATGGACATCTGATATAATAGACAAAAAAAATAACCAT AAATTATATGGATTTATAAAAGAACACCCAAATAATTTAAAAATATATATTAAAAATACTTCGTATTTTAAGAATAATAT AAATAAAATTAATTAA
Upstream 100 bases:
>100_bases TTCAATAAATAAATAAATAATATAAACGAAACAAGAACAAAATGAGGGGATAATTATCACAATATCATTAAATGAATTTT GGGAATGTATTGAATCAATA
Downstream 100 bases:
>100_bases AAAAATGGGGAATTAATATGATGGAATTAAATTCCTATAAATCCTTAAAAATAAAGAAAAAGGAAGAAAAGGAAAAAATA AAGCAAAGATACAGTATTAC
Product: UvrD/REP helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 751; Mature: 750
Protein sequence:
>751_residues MGYKFNEEQKNSVNHKDNPLWVVAGPGSGKTEVLVVRTLKLIFVDGVNPKSIILTTFTKKASQNLFDRIIKYSTKLYDLY PELKGSSIEIHSLRVGTLHSLCNDIMKEYKYTDYENYKLINEIENYIFVYNYCPIAKYGARYKEIWTKFRCLVGRYDKDL CCQIIDYKNKARLTSATITLFNRIIEDKVNIDKLKNGKIYHKKLAEECEKYLEKLEGFKLCTFSTIQLKFIDFLNSEDGE LFLSGSGYNPPIKHIMVDEYQDTNPIQEEIYFKMAKQIENNNLCVVGDDDQAMYRFRGGTVECMVNFDKTCVEKFNIPID KINKIFLKSNYRSHPDIVKYYDDYINSYKYTKDVEMERARVKDKPQLVAKKEMDKETIDNYLALNYIEKEDDEKLAEEVA NTIKYFKDNDIIEDYSQCVILIKSTREIDYNGNDSFIGHIRQKLLNNGIDIYNPRSKNFLNQEEIKLALGAFISIVDTDI SVLENNLRSQPISNEVVKWYEEYQNNKNKYPELKKYVDSSVEKLKTMEEGSFINSSIENILYKIYACYPFTEWLNDEEKS YRLAKLTNLFNSYSTIPTENLISKGSISIDGHTKGKVDVKWLIEFYGSLVGHFLGGIDDIEDEEITIPEGKVPIMTVHQA KGLEFPFVFVYLQKWQNKANDGAILEREFAEFTDFKRISTIPRKKTFQDIIRFHYVAYSRAQYGLIHLWTSDIIDKKNNH KLYGFIKEHPNNLKIYIKNTSYFKNNINKIN
Sequences:
>Translated_751_residues MGYKFNEEQKNSVNHKDNPLWVVAGPGSGKTEVLVVRTLKLIFVDGVNPKSIILTTFTKKASQNLFDRIIKYSTKLYDLY PELKGSSIEIHSLRVGTLHSLCNDIMKEYKYTDYENYKLINEIENYIFVYNYCPIAKYGARYKEIWTKFRCLVGRYDKDL CCQIIDYKNKARLTSATITLFNRIIEDKVNIDKLKNGKIYHKKLAEECEKYLEKLEGFKLCTFSTIQLKFIDFLNSEDGE LFLSGSGYNPPIKHIMVDEYQDTNPIQEEIYFKMAKQIENNNLCVVGDDDQAMYRFRGGTVECMVNFDKTCVEKFNIPID KINKIFLKSNYRSHPDIVKYYDDYINSYKYTKDVEMERARVKDKPQLVAKKEMDKETIDNYLALNYIEKEDDEKLAEEVA NTIKYFKDNDIIEDYSQCVILIKSTREIDYNGNDSFIGHIRQKLLNNGIDIYNPRSKNFLNQEEIKLALGAFISIVDTDI SVLENNLRSQPISNEVVKWYEEYQNNKNKYPELKKYVDSSVEKLKTMEEGSFINSSIENILYKIYACYPFTEWLNDEEKS YRLAKLTNLFNSYSTIPTENLISKGSISIDGHTKGKVDVKWLIEFYGSLVGHFLGGIDDIEDEEITIPEGKVPIMTVHQA KGLEFPFVFVYLQKWQNKANDGAILEREFAEFTDFKRISTIPRKKTFQDIIRFHYVAYSRAQYGLIHLWTSDIIDKKNNH KLYGFIKEHPNNLKIYIKNTSYFKNNINKIN >Mature_750_residues GYKFNEEQKNSVNHKDNPLWVVAGPGSGKTEVLVVRTLKLIFVDGVNPKSIILTTFTKKASQNLFDRIIKYSTKLYDLYP ELKGSSIEIHSLRVGTLHSLCNDIMKEYKYTDYENYKLINEIENYIFVYNYCPIAKYGARYKEIWTKFRCLVGRYDKDLC CQIIDYKNKARLTSATITLFNRIIEDKVNIDKLKNGKIYHKKLAEECEKYLEKLEGFKLCTFSTIQLKFIDFLNSEDGEL FLSGSGYNPPIKHIMVDEYQDTNPIQEEIYFKMAKQIENNNLCVVGDDDQAMYRFRGGTVECMVNFDKTCVEKFNIPIDK INKIFLKSNYRSHPDIVKYYDDYINSYKYTKDVEMERARVKDKPQLVAKKEMDKETIDNYLALNYIEKEDDEKLAEEVAN TIKYFKDNDIIEDYSQCVILIKSTREIDYNGNDSFIGHIRQKLLNNGIDIYNPRSKNFLNQEEIKLALGAFISIVDTDIS VLENNLRSQPISNEVVKWYEEYQNNKNKYPELKKYVDSSVEKLKTMEEGSFINSSIENILYKIYACYPFTEWLNDEEKSY RLAKLTNLFNSYSTIPTENLISKGSISIDGHTKGKVDVKWLIEFYGSLVGHFLGGIDDIEDEEITIPEGKVPIMTVHQAK GLEFPFVFVYLQKWQNKANDGAILEREFAEFTDFKRISTIPRKKTFQDIIRFHYVAYSRAQYGLIHLWTSDIIDKKNNHK LYGFIKEHPNNLKIYIKNTSYFKNNINKIN
Specific function: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Saccharomyces cerevisiae, GI6322369, Length=107, Percent_Identity=36.4485981308411, Blast_Score=70, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005752 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 87984; Mature: 87853
Theoretical pI: Translated: 7.00; Mature: 7.00
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGYKFNEEQKNSVNHKDNPLWVVAGPGSGKTEVLVVRTLKLIFVDGVNPKSIILTTFTKK CCCCCCCHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHHH ASQNLFDRIIKYSTKLYDLYPELKGSSIEIHSLRVGTLHSLCNDIMKEYKYTDYENYKLI HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHH NEIENYIFVYNYCPIAKYGARYKEIWTKFRCLVGRYDKDLCCQIIDYKNKARLTSATITL HHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH FNRIIEDKVNIDKLKNGKIYHKKLAEECEKYLEKLEGFKLCTFSTIQLKFIDFLNSEDGE HHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEHHHCCCCCE LFLSGSGYNPPIKHIMVDEYQDTNPIQEEIYFKMAKQIENNNLCVVGDDDQAMYRFRGGT EEEECCCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCE VECMVNFDKTCVEKFNIPIDKINKIFLKSNYRSHPDIVKYYDDYINSYKYTKDVEMERAR EEEEEECCHHHHHHHCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH VKDKPQLVAKKEMDKETIDNYLALNYIEKEDDEKLAEEVANTIKYFKDNDIIEDYSQCVI CCCCHHHHHHHHCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEE LIKSTREIDYNGNDSFIGHIRQKLLNNGIDIYNPRSKNFLNQEEIKLALGAFISIVDTDI EEECCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH SVLENNLRSQPISNEVVKWYEEYQNNKNKYPELKKYVDSSVEKLKTMEEGSFINSSIENI HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH LYKIYACYPFTEWLNDEEKSYRLAKLTNLFNSYSTIPTENLISKGSISIDGHTKGKVDVK HHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCHHH WLIEFYGSLVGHFLGGIDDIEDEEITIPEGKVPIMTVHQAKGLEFPFVFVYLQKWQNKAN HHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCC DGAILEREFAEFTDFKRISTIPRKKTFQDIIRFHYVAYSRAQYGLIHLWTSDIIDKKNNH CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCC KLYGFIKEHPNNLKIYIKNTSYFKNNINKIN EEEEEEECCCCCEEEEEECCHHHHCCCCCCC >Mature Secondary Structure GYKFNEEQKNSVNHKDNPLWVVAGPGSGKTEVLVVRTLKLIFVDGVNPKSIILTTFTKK CCCCCCHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHHH ASQNLFDRIIKYSTKLYDLYPELKGSSIEIHSLRVGTLHSLCNDIMKEYKYTDYENYKLI HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHH NEIENYIFVYNYCPIAKYGARYKEIWTKFRCLVGRYDKDLCCQIIDYKNKARLTSATITL HHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH FNRIIEDKVNIDKLKNGKIYHKKLAEECEKYLEKLEGFKLCTFSTIQLKFIDFLNSEDGE HHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEHHHCCCCCE LFLSGSGYNPPIKHIMVDEYQDTNPIQEEIYFKMAKQIENNNLCVVGDDDQAMYRFRGGT EEEECCCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCE VECMVNFDKTCVEKFNIPIDKINKIFLKSNYRSHPDIVKYYDDYINSYKYTKDVEMERAR EEEEEECCHHHHHHHCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH VKDKPQLVAKKEMDKETIDNYLALNYIEKEDDEKLAEEVANTIKYFKDNDIIEDYSQCVI CCCCHHHHHHHHCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEE LIKSTREIDYNGNDSFIGHIRQKLLNNGIDIYNPRSKNFLNQEEIKLALGAFISIVDTDI EEECCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH SVLENNLRSQPISNEVVKWYEEYQNNKNKYPELKKYVDSSVEKLKTMEEGSFINSSIENI HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH LYKIYACYPFTEWLNDEEKSYRLAKLTNLFNSYSTIPTENLISKGSISIDGHTKGKVDVK HHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCHHH WLIEFYGSLVGHFLGGIDDIEDEEITIPEGKVPIMTVHQAKGLEFPFVFVYLQKWQNKAN HHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCC DGAILEREFAEFTDFKRISTIPRKKTFQDIIRFHYVAYSRAQYGLIHLWTSDIIDKKNNH CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCC KLYGFIKEHPNNLKIYIKNTSYFKNNINKIN EEEEEEECCCCCEEEEEECCHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]