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The map label for this gene is cdhE [H]

Identifier: 150400649

GI number: 150400649

Start: 228756

End: 230225

Strand: Direct

Name: cdhE [H]

Synonym: Maeo_0211

Alternate gene names: 150400649

Gene position: 228756-230225 (Clockwise)

Preceding gene: 150400648

Following gene: 150400650

Centisome position: 14.58

GC content: 34.42

Gene sequence:

>1470_bases
ATGGCTAAAATAAGTGCGATGGATATTTACAAATTACTTCCGAAAACAAACTGTAAAAAATGTGGGGAAGCTTCCTGCAT
GGCATTTGCTACCAAATTACAAAATAAAAAGGCGATGGTAGAGGAATGCCCCATAATGAATGCCCCAAAATTTGAAGCAA
AAAAGAAAGAGCTCGTAGAATTATTATCTCCACCAGTTAAGGAGGTATGGTTTGGATATGATGATAAAAATCATAGGGCT
ACAATGGGTGGAGACGAAGTAATGTATAGGTATGAATTAACATATTATAACCCTGCACCATTTGGAATAGATATATCTGA
CAATTTATCAGATAATGAAATAAAAGAAAGAGCAAAATATATTGAAAATTTTGTATTTGAAAGAACAGGGGAGAAATTAA
CTCTTGATTTTATAGCACTTAGAAATGCGTCAAATGATCCAGAAAAATTTAAAAATGCTTTACAAATCATTCAAGAAAAC
ACCAAAATGCCAATATCTTTATGCTCTATTAATCCAGAAAGCATAGAAGAAGCTTTAAAAATAATAAACTCTAAACCATT
AATTTATGCCGCCACAGAGGACAATTTTGAAAAGATGCTTAATGTTCTTTTAAAACACAAAAAAGAAACCAATAAAGAAT
TTGCATTAGTTTTATCCTCGAAACAGATAAAAACATTAAAAGGAATGGCAAAAGAATGTTTGAACCACGGAATTGATGAT
TTAGTATTAGAACCACATACACACCCCGAAAATATATCGGAAACATTGGACAAATTCATAGCATTGAGGAGAAGTGCCAT
TGAGAAAGAAGATAAATTGTTAGGATTCCCAATATTGGGATTGCCAATAAACACCTATTTTTATACCCTTAACAATAACT
CTATTTCTCAATTTATTGAAGAACCCAATAAAGCTGCGGGAATAATGGAGGCAAGAACTGCAAACACTATGTTAATTAGG
TATGCTGATGCCATTATACTACACGGATGTGAAATTTGGGAGCTCATGCCAGTATTGACTCTTAGACAGGCACTATACAC
TGACCCAAGAAAGCCACAGGCAGTAGATGCCGATATATATCCAATAGGAAATCCAGATGCAGATAGTCCGGTGATTATGA
CCACAAACTTCTCTTTAACATATTATACTGTTACAGGTGATTTTGAGAAAGATGGCGTTAAATGCTGGTTAATTGTATTG
GATACAGAGGGTAAAGCCGTAGATGTTGCCGTAGCTGGTGGTCAATACAACGGTGAAAATGCTAAAAACCTAATTGAGGA
AAAAGGTTTGGCCGATAAAGTTAATCATAATGTAATCATATTGCCTGGATTGGGAGCTCCTGCAAGGGGAGACATCGAGG
AAAAAACAGGTTGGAATTGTGTAGTTGGAACAAGGGATTCTTCACAGGTTGGAGACTTCTTGAAGAAAAACTGGGAAAAT
ATATTGGAAAAAATAGGAAAAAATAATTAA

Upstream 100 bases:

>100_bases
GGATTAAAGCATAAAAATTATTTATTATATATTAATATATTAATATGTTATTATTATTATTATTATTATTATTATTTCTA
CATATTATTTCGGTGATATA

Downstream 100 bases:

>100_bases
TATTTTCCATATATTTTATATTTATTTTAATTTTTAGTATATTTTAGTATATTTTATTGTGTATATTATAATTGATGTAA
TTATTAATTAAAATACTTTG

Product: acetyl-CoA decarbonylase/synthase complex subunit gamma

Products: CO2; AH2

Alternate protein names: ACDS complex subunit gamma; ACDS complex methyltransferase; Corrinoid/iron-sulfur component large subunit [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MAKISAMDIYKLLPKTNCKKCGEASCMAFATKLQNKKAMVEECPIMNAPKFEAKKKELVELLSPPVKEVWFGYDDKNHRA
TMGGDEVMYRYELTYYNPAPFGIDISDNLSDNEIKERAKYIENFVFERTGEKLTLDFIALRNASNDPEKFKNALQIIQEN
TKMPISLCSINPESIEEALKIINSKPLIYAATEDNFEKMLNVLLKHKKETNKEFALVLSSKQIKTLKGMAKECLNHGIDD
LVLEPHTHPENISETLDKFIALRRSAIEKEDKLLGFPILGLPINTYFYTLNNNSISQFIEEPNKAAGIMEARTANTMLIR
YADAIILHGCEIWELMPVLTLRQALYTDPRKPQAVDADIYPIGNPDADSPVIMTTNFSLTYYTVTGDFEKDGVKCWLIVL
DTEGKAVDVAVAGGQYNGENAKNLIEEKGLADKVNHNVIILPGLGAPARGDIEEKTGWNCVVGTRDSSQVGDFLKKNWEN
ILEKIGKNN

Sequences:

>Translated_489_residues
MAKISAMDIYKLLPKTNCKKCGEASCMAFATKLQNKKAMVEECPIMNAPKFEAKKKELVELLSPPVKEVWFGYDDKNHRA
TMGGDEVMYRYELTYYNPAPFGIDISDNLSDNEIKERAKYIENFVFERTGEKLTLDFIALRNASNDPEKFKNALQIIQEN
TKMPISLCSINPESIEEALKIINSKPLIYAATEDNFEKMLNVLLKHKKETNKEFALVLSSKQIKTLKGMAKECLNHGIDD
LVLEPHTHPENISETLDKFIALRRSAIEKEDKLLGFPILGLPINTYFYTLNNNSISQFIEEPNKAAGIMEARTANTMLIR
YADAIILHGCEIWELMPVLTLRQALYTDPRKPQAVDADIYPIGNPDADSPVIMTTNFSLTYYTVTGDFEKDGVKCWLIVL
DTEGKAVDVAVAGGQYNGENAKNLIEEKGLADKVNHNVIILPGLGAPARGDIEEKTGWNCVVGTRDSSQVGDFLKKNWEN
ILEKIGKNN
>Mature_488_residues
AKISAMDIYKLLPKTNCKKCGEASCMAFATKLQNKKAMVEECPIMNAPKFEAKKKELVELLSPPVKEVWFGYDDKNHRAT
MGGDEVMYRYELTYYNPAPFGIDISDNLSDNEIKERAKYIENFVFERTGEKLTLDFIALRNASNDPEKFKNALQIIQENT
KMPISLCSINPESIEEALKIINSKPLIYAATEDNFEKMLNVLLKHKKETNKEFALVLSSKQIKTLKGMAKECLNHGIDDL
VLEPHTHPENISETLDKFIALRRSAIEKEDKLLGFPILGLPINTYFYTLNNNSISQFIEEPNKAAGIMEARTANTMLIRY
ADAIILHGCEIWELMPVLTLRQALYTDPRKPQAVDADIYPIGNPDADSPVIMTTNFSLTYYTVTGDFEKDGVKCWLIVLD
TEGKAVDVAVAGGQYNGENAKNLIEEKGLADKVNHNVIILPGLGAPARGDIEEKTGWNCVVGTRDSSQVGDFLKKNWENI
LEKIGKNN

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) [H]

COG id: COG1456

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016041
- InterPro:   IPR016218
- InterPro:   IPR011005
- InterPro:   IPR007202
- InterPro:   IPR000489 [H]

Pfam domain/function: PF03599 CdhD; PF04060 FeS [H]

EC number: 1.2.99.2

Molecular weight: Translated: 54946; Mature: 54815

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKISAMDIYKLLPKTNCKKCGEASCMAFATKLQNKKAMVEECPIMNAPKFEAKKKELVE
CCCCHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHH
LLSPPVKEVWFGYDDKNHRATMGGDEVMYRYELTYYNPAPFGIDISDNLSDNEIKERAKY
HHCCCHHHHHCCCCCCCCEEECCCCEEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHH
IENFVFERTGEKLTLDFIALRNASNDPEKFKNALQIIQENTKMPISLCSINPESIEEALK
HHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
IINSKPLIYAATEDNFEKMLNVLLKHKKETNKEFALVLSSKQIKTLKGMAKECLNHGIDD
HHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
LVLEPHTHPENISETLDKFIALRRSAIEKEDKLLGFPILGLPINTYFYTLNNNSISQFIE
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCEEECEEEEEEEEEECCCHHHHHHH
EPNKAAGIMEARTANTMLIRYADAIILHGCEIWELMPVLTLRQALYTDPRKPQAVDADIY
CCCHHCCHHHHCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
PIGNPDADSPVIMTTNFSLTYYTVTGDFEKDGVKCWLIVLDTEGKAVDVAVAGGQYNGEN
ECCCCCCCCCEEEEEECEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCH
AKNLIEEKGLADKVNHNVIILPGLGAPARGDIEEKTGWNCVVGTRDSSQVGDFLKKNWEN
HHHHHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ILEKIGKNN
HHHHHCCCC
>Mature Secondary Structure 
AKISAMDIYKLLPKTNCKKCGEASCMAFATKLQNKKAMVEECPIMNAPKFEAKKKELVE
CCCHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHH
LLSPPVKEVWFGYDDKNHRATMGGDEVMYRYELTYYNPAPFGIDISDNLSDNEIKERAKY
HHCCCHHHHHCCCCCCCCEEECCCCEEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHH
IENFVFERTGEKLTLDFIALRNASNDPEKFKNALQIIQENTKMPISLCSINPESIEEALK
HHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
IINSKPLIYAATEDNFEKMLNVLLKHKKETNKEFALVLSSKQIKTLKGMAKECLNHGIDD
HHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
LVLEPHTHPENISETLDKFIALRRSAIEKEDKLLGFPILGLPINTYFYTLNNNSISQFIE
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCEEECEEEEEEEEEECCCHHHHHHH
EPNKAAGIMEARTANTMLIRYADAIILHGCEIWELMPVLTLRQALYTDPRKPQAVDADIY
CCCHHCCHHHHCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
PIGNPDADSPVIMTTNFSLTYYTVTGDFEKDGVKCWLIVLDTEGKAVDVAVAGGQYNGEN
ECCCCCCCCCEEEEEECEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCH
AKNLIEEKGLADKVNHNVIILPGLGAPARGDIEEKTGWNCVVGTRDSSQVGDFLKKNWEN
HHHHHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ILEKIGKNN
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]