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The map label for this gene is truA [H]

Identifier: 150400596

GI number: 150400596

Start: 177196

End: 178128

Strand: Direct

Name: truA [H]

Synonym: Maeo_0158

Alternate gene names: 150400596

Gene position: 177196-178128 (Clockwise)

Preceding gene: 150400594

Following gene: 150400597

Centisome position: 11.29

GC content: 28.19

Gene sequence:

>933_bases
ATGAATAATAAAATTAACGATAATAGTAATAAGTGTAGTAATAATATTAATAACAATTGTGATAATAAGCTAACCCATTG
GGAAAAAGTTGCCAAAAGAATTAACGAAAATACATATATTTTAAAAATAGCCTACGATGGAAATAATGACGGTTTTCAAA
GCCACCCTCATAAAAAAAATAATGTATGTGATATTATAATTAATGCACTATTAAAATGTGGATATATGGATAAAGAGGAA
ACAAAACCACTATTGCGAGGGGGTAGAACAGATAATGGAGTATTGGCATTGGGAAATTTTATAATTGTAAATTTAAACCA
AGAACCTATATTGTCCCATGTTTATGCCAAATTAAAATATACTGGCGTATGGGTATTAGGATATAGTAAAATCTCGGAGC
TCCCTGAAATTAAATATAGGCATTATAAATATATACTACCAAATGAAGGACAAAATATAAATTTAATGATAGAGGGGGCA
AATAAATTAATCGGAACTCATTCCTTTCATAATTTATCAAAAAGAGATAATACAAAAAATAAAAACCCATTACGGACAAT
ATATGATATAAAAATAAAAGAAAATGATTTTTTCATTACTATTGATATTTTTGGTAAAAATTTTTTATGGAATATGGTGA
GGCGAATAGTTACAGCACTATCGGAAGTAGGAAAAGAAAATAAGCCTTTAAATTGGATTGATAAATTACTGGATATAAAC
CATACAGAAGGTGTTGCCCCAGCTCCTGCAAATGGGCTTATTTTGGTAGATGTAAAAACAAATATAAATTATATACGGGA
CGATTATGTAATTGGAAAATTTAAAGAAGAATGGAGAAAGAATTACAGAAAAAACACAGCAGATGCTGGGGTAAGTATGA
ATATGTTAAATATAGTCAATCTTCAAAAACTGTCCTATGATAGTCCAAAATAA

Upstream 100 bases:

>100_bases
GTCCGAAGATTGACTATAAATATATAATTAAATATATATGTTATCATCAGTTTAATATAACAAATTAATTAAAATTAATT
AACTATATACTAGGGACAGT

Downstream 100 bases:

>100_bases
TTAAATAATTATAGGTTTAATATTATATGTATTATGCATAATACAGTCTTATCTGCGTATCCTATGTGTGAAAAAGTTCG
AAGATTGGCTATAAATTCAA

Product: tRNA pseudouridine synthase A

Products: NA

Alternate protein names: tRNA pseudouridylate synthase I; tRNA-uridine isomerase I [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNNKINDNSNKCSNNINNNCDNKLTHWEKVAKRINENTYILKIAYDGNNDGFQSHPHKKNNVCDIIINALLKCGYMDKEE
TKPLLRGGRTDNGVLALGNFIIVNLNQEPILSHVYAKLKYTGVWVLGYSKISELPEIKYRHYKYILPNEGQNINLMIEGA
NKLIGTHSFHNLSKRDNTKNKNPLRTIYDIKIKENDFFITIDIFGKNFLWNMVRRIVTALSEVGKENKPLNWIDKLLDIN
HTEGVAPAPANGLILVDVKTNINYIRDDYVIGKFKEEWRKNYRKNTADAGVSMNMLNIVNLQKLSYDSPK

Sequences:

>Translated_310_residues
MNNKINDNSNKCSNNINNNCDNKLTHWEKVAKRINENTYILKIAYDGNNDGFQSHPHKKNNVCDIIINALLKCGYMDKEE
TKPLLRGGRTDNGVLALGNFIIVNLNQEPILSHVYAKLKYTGVWVLGYSKISELPEIKYRHYKYILPNEGQNINLMIEGA
NKLIGTHSFHNLSKRDNTKNKNPLRTIYDIKIKENDFFITIDIFGKNFLWNMVRRIVTALSEVGKENKPLNWIDKLLDIN
HTEGVAPAPANGLILVDVKTNINYIRDDYVIGKFKEEWRKNYRKNTADAGVSMNMLNIVNLQKLSYDSPK
>Mature_310_residues
MNNKINDNSNKCSNNINNNCDNKLTHWEKVAKRINENTYILKIAYDGNNDGFQSHPHKKNNVCDIIINALLKCGYMDKEE
TKPLLRGGRTDNGVLALGNFIIVNLNQEPILSHVYAKLKYTGVWVLGYSKISELPEIKYRHYKYILPNEGQNINLMIEGA
NKLIGTHSFHNLSKRDNTKNKNPLRTIYDIKIKENDFFITIDIFGKNFLWNMVRRIVTALSEVGKENKPLNWIDKLLDIN
HTEGVAPAPANGLILVDVKTNINYIRDDYVIGKFKEEWRKNYRKNTADAGVSMNMLNIVNLQKLSYDSPK

Specific function: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs [H]

COG id: COG0101

COG function: function code J; Pseudouridylate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA pseudouridine synthase truA family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71985046, Length=234, Percent_Identity=26.0683760683761, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001406
- InterPro:   IPR020097
- InterPro:   IPR020095
- InterPro:   IPR020094 [H]

Pfam domain/function: PF01416 PseudoU_synth_1 [H]

EC number: =5.4.99.12 [H]

Molecular weight: Translated: 35670; Mature: 35670

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKINDNSNKCSNNINNNCDNKLTHWEKVAKRINENTYILKIAYDGNNDGFQSHPHKKN
CCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCC
NVCDIIINALLKCGYMDKEETKPLLRGGRTDNGVLALGNFIIVNLNQEPILSHVYAKLKY
CHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHEE
TGVWVLGYSKISELPEIKYRHYKYILPNEGQNINLMIEGANKLIGTHSFHNLSKRDNTKN
EEEEEEEHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHCCHHCCCCCC
KNPLRTIYDIKIKENDFFITIDIFGKNFLWNMVRRIVTALSEVGKENKPLNWIDKLLDIN
CCCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
HTEGVAPAPANGLILVDVKTNINYIRDDYVIGKFKEEWRKNYRKNTADAGVSMNMLNIVN
CCCCCCCCCCCCEEEEEEECCCCEEECCEEEEHHHHHHHHHHCCCCCCCCCEEEHHHHEE
LQKLSYDSPK
HHHCCCCCCC
>Mature Secondary Structure
MNNKINDNSNKCSNNINNNCDNKLTHWEKVAKRINENTYILKIAYDGNNDGFQSHPHKKN
CCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCC
NVCDIIINALLKCGYMDKEETKPLLRGGRTDNGVLALGNFIIVNLNQEPILSHVYAKLKY
CHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHEE
TGVWVLGYSKISELPEIKYRHYKYILPNEGQNINLMIEGANKLIGTHSFHNLSKRDNTKN
EEEEEEEHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHCCHHCCCCCC
KNPLRTIYDIKIKENDFFITIDIFGKNFLWNMVRRIVTALSEVGKENKPLNWIDKLLDIN
CCCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
HTEGVAPAPANGLILVDVKTNINYIRDDYVIGKFKEEWRKNYRKNTADAGVSMNMLNIVN
CCCCCCCCCCCCEEEEEEECCCCEEECCEEEEHHHHHHHHHHCCCCCCCCCEEEHHHHEE
LQKLSYDSPK
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]