Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 150400445

GI number: 150400445

Start: 5810

End: 7114

Strand: Reverse

Name: pgi [H]

Synonym: Maeo_0006

Alternate gene names: 150400445

Gene position: 7114-5810 (Counterclockwise)

Preceding gene: 150400446

Following gene: 150400444

Centisome position: 0.45

GC content: 29.73

Gene sequence:

>1305_bases
ATGAACATAGAATTAAATTACACAAATATCATGGATGAAATTATATATGAAGAGGGGATATCACTCTTAGATTTTGTGAA
CATAAAAGAGAAAATAAATACGGCATATGACAAGGTTATGCAAAAATGCAAAAATGATGAATTAGGATTTATGAAGATTA
TTTATGATGATATATTGATATATTATGAACTAAAAGAATATTCAAAAGATTTTGACAATATAGTAGTTATTGGAATGGGG
GGTTCAATATTGGGAACTCAGGCAATATATGAAGGAGTAAAAGGAATACACTACAATGACCTTAATGATAAAAAGGTATA
TTTTTTGGATAATTCTGACCCAGAAAAAACTTTTGAGATTTTAAATATTATTAATTTAAAAAAAACATTGGTATTTGCCA
TAAGCAAATCTGGAAATACTGCTGAAACTCTTGCAAATTTTTTGATAATTGAAGAAAAATTGAAAGGCATAACAAAGGAT
TATAAAAAAAATATTGTGGTAGTTGCAAATACTGGCGAATTAAAAAATATTGCAGATAGGGAAGGATATAAATTTTATAG
AATGCCCGAAAATGTTGGAGGAAGATTTTCTGTATTTTCTGCTGTGGGACTAGCCCCACTATGCTGTATGGATATAGATA
TTGAAGCACTAATCGAAGGGGCAAAGGAAATGGACAAATTATGTAGGAATAAAGATATTTTTAAAAATCCTGCATTAATG
AACGCCACAATACATTATATTGCCTACAATAAGGGAAAAACTATTTCTGTGCTTATGCCATATATTGAGAGATTGCATAA
ATTTGGACTATGGTATAGGCAATTATGGGCCGAAAGTATAGGTAAAAATGGGATTGGACAAACTCCCGTTATATCCCTTG
GTGCAAAAGACCAGCATTCTCAGCTTCAATTATATATGGATGGATTAAAAAATATAATTATTACATTTATAACCGTGCAT
AAATTCAAATATGATTTAAAAATACGGAGCTCCAACTATCTAAACAATCGGACTTTATCAACGCTAATACACAGTGAGCA
AAAAGGAACTGAAATTTCACTAACTAATAATAAAATTCCAAATATTAGTATCAATATAGATGAATTAAATGAATATACTA
TTGGAAAATTAATATATTTATATGAGATGCAGACGGCATTCATGGGGGAGCTCCTTGAAATTAATGCTTTTAACCAGCCA
GCAGTTGAAGGAGGTAAAATAATTACGCGGAAATTATTGGAGGAATGTCCAGTTGATGAAATAAAAGAGTCCAAACCTAC
TAAAAAATATTGCATTGAAATATAA

Upstream 100 bases:

>100_bases
TGTATAGATATGAAAATTTAAAGGATTTTATATGTGGTCTGTTCGAGAACTTTTTACATCAAATAATTAATGATATATAA
TTAAGAATAGAGGGGAAATA

Downstream 100 bases:

>100_bases
AATATCCTTTAAATATGTATTTTTAGTATTTTTGTATATTCCGCATTGATATAATCAATATTTGCTGTTTTTTTGGTGGT
GCAATTATGGATACAAGTTG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNIELNYTNIMDEIIYEEGISLLDFVNIKEKINTAYDKVMQKCKNDELGFMKIIYDDILIYYELKEYSKDFDNIVVIGMG
GSILGTQAIYEGVKGIHYNDLNDKKVYFLDNSDPEKTFEILNIINLKKTLVFAISKSGNTAETLANFLIIEEKLKGITKD
YKKNIVVVANTGELKNIADREGYKFYRMPENVGGRFSVFSAVGLAPLCCMDIDIEALIEGAKEMDKLCRNKDIFKNPALM
NATIHYIAYNKGKTISVLMPYIERLHKFGLWYRQLWAESIGKNGIGQTPVISLGAKDQHSQLQLYMDGLKNIIITFITVH
KFKYDLKIRSSNYLNNRTLSTLIHSEQKGTEISLTNNKIPNISINIDELNEYTIGKLIYLYEMQTAFMGELLEINAFNQP
AVEGGKIITRKLLEECPVDEIKESKPTKKYCIEI

Sequences:

>Translated_434_residues
MNIELNYTNIMDEIIYEEGISLLDFVNIKEKINTAYDKVMQKCKNDELGFMKIIYDDILIYYELKEYSKDFDNIVVIGMG
GSILGTQAIYEGVKGIHYNDLNDKKVYFLDNSDPEKTFEILNIINLKKTLVFAISKSGNTAETLANFLIIEEKLKGITKD
YKKNIVVVANTGELKNIADREGYKFYRMPENVGGRFSVFSAVGLAPLCCMDIDIEALIEGAKEMDKLCRNKDIFKNPALM
NATIHYIAYNKGKTISVLMPYIERLHKFGLWYRQLWAESIGKNGIGQTPVISLGAKDQHSQLQLYMDGLKNIIITFITVH
KFKYDLKIRSSNYLNNRTLSTLIHSEQKGTEISLTNNKIPNISINIDELNEYTIGKLIYLYEMQTAFMGELLEINAFNQP
AVEGGKIITRKLLEECPVDEIKESKPTKKYCIEI
>Mature_434_residues
MNIELNYTNIMDEIIYEEGISLLDFVNIKEKINTAYDKVMQKCKNDELGFMKIIYDDILIYYELKEYSKDFDNIVVIGMG
GSILGTQAIYEGVKGIHYNDLNDKKVYFLDNSDPEKTFEILNIINLKKTLVFAISKSGNTAETLANFLIIEEKLKGITKD
YKKNIVVVANTGELKNIADREGYKFYRMPENVGGRFSVFSAVGLAPLCCMDIDIEALIEGAKEMDKLCRNKDIFKNPALM
NATIHYIAYNKGKTISVLMPYIERLHKFGLWYRQLWAESIGKNGIGQTPVISLGAKDQHSQLQLYMDGLKNIIITFITVH
KFKYDLKIRSSNYLNNRTLSTLIHSEQKGTEISLTNNKIPNISINIDELNEYTIGKLIYLYEMQTAFMGELLEINAFNQP
AVEGGKIITRKLLEECPVDEIKESKPTKKYCIEI

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=436, Percent_Identity=26.8348623853211, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI296080693, Length=352, Percent_Identity=27.5568181818182, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790457, Length=404, Percent_Identity=26.980198019802, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71996703, Length=415, Percent_Identity=26.2650602409639, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71996708, Length=415, Percent_Identity=26.2650602409639, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319673, Length=395, Percent_Identity=28.6075949367089, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651916, Length=396, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24651914, Length=396, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737445, Length=396, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 49627; Mature: 49627

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIELNYTNIMDEIIYEEGISLLDFVNIKEKINTAYDKVMQKCKNDELGFMKIIYDDILI
CEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHE
YYELKEYSKDFDNIVVIGMGGSILGTQAIYEGVKGIHYNDLNDKKVYFLDNSDPEKTFEI
EEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEECCCCCCEEEEECCCCHHHHHHH
LNIINLKKTLVFAISKSGNTAETLANFLIIEEKLKGITKDYKKNIVVVANTGELKNIADR
HHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
EGYKFYRMPENVGGRFSVFSAVGLAPLCCMDIDIEALIEGAKEMDKLCRNKDIFKNPALM
CCCEEEECCCCCCCCCHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCE
NATIHYIAYNKGKTISVLMPYIERLHKFGLWYRQLWAESIGKNGIGQTPVISLGAKDQHS
EEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHH
QLQLYMDGLKNIIITFITVHKFKYDLKIRSSNYLNNRTLSTLIHSEQKGTEISLTNNKIP
HHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCC
NISINIDELNEYTIGKLIYLYEMQTAFMGELLEINAFNQPAVEGGKIITRKLLEECPVDE
EEEEEHHCCCCCHHHHEEEEEEHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCHHH
IKESKPTKKYCIEI
HHCCCCCHHHEECC
>Mature Secondary Structure
MNIELNYTNIMDEIIYEEGISLLDFVNIKEKINTAYDKVMQKCKNDELGFMKIIYDDILI
CEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHE
YYELKEYSKDFDNIVVIGMGGSILGTQAIYEGVKGIHYNDLNDKKVYFLDNSDPEKTFEI
EEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEECCCCCCEEEEECCCCHHHHHHH
LNIINLKKTLVFAISKSGNTAETLANFLIIEEKLKGITKDYKKNIVVVANTGELKNIADR
HHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
EGYKFYRMPENVGGRFSVFSAVGLAPLCCMDIDIEALIEGAKEMDKLCRNKDIFKNPALM
CCCEEEECCCCCCCCCHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCE
NATIHYIAYNKGKTISVLMPYIERLHKFGLWYRQLWAESIGKNGIGQTPVISLGAKDQHS
EEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHH
QLQLYMDGLKNIIITFITVHKFKYDLKIRSSNYLNNRTLSTLIHSEQKGTEISLTNNKIP
HHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCC
NISINIDELNEYTIGKLIYLYEMQTAFMGELLEINAFNQPAVEGGKIITRKLLEECPVDE
EEEEEHHCCCCCHHHHEEEEEEHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCHHH
IKESKPTKKYCIEI
HHCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA