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The map label for this gene is purQ [H]

Identifier: 150399925

GI number: 150399925

Start: 1196182

End: 1196991

Strand: Reverse

Name: purQ [H]

Synonym: Mevan_1182

Alternate gene names: 150399925

Gene position: 1196991-1196182 (Counterclockwise)

Preceding gene: 150399926

Following gene: 150399924

Centisome position: 69.59

GC content: 31.73

Gene sequence:

>810_bases
GTGGTTCCAAAAGTACTTATAATGTCTGGATACGGCATAAACTGCGAAGCAGAAACTGCACATGCATTTCAATTGGCAGG
TGCAAAAACAGATATTGTGCATATTAACGATTTAATAGCCGGAAAAAAGAAAATGAAAGATTATGAAATAATAATGTTTC
CAGGCGGATTTTCATACGGGGATGATACCGGTTCAGGAAATGCATTTGCGAACAAAATTAAAAATAACTTGTTTGAAGAC
CTGAAAGAATTTATTGACTCTGGAAAACTCATTCTTGGTATTTGTAACGGTTTTCAGGTTATGACTAATCTAGGTTTGTT
TAAAATACCTGACAAAAATTATGGAGATAGGATTTCTGCACTTCAATCAAATTTAAATAATAGATATGAATGTAGATGGG
TTCATATTAAAGAAAATAACTCCATATGTATATTTACAAAGGGTATCGATGTTCTCCATGTCCCAATAGCTCACGGTGAA
GGTAGATTTTATTGTGATATTGAAACATTTGAAAAGTTAAAGGAAAATAACCAAATTGTATTTACTTACTGTAACGAATC
AGGAGATTTTGCAAATTTAGAGTACCCTTTAAATCCAAATGGTGCACTTTATGATATTGCGGGAATTTGTGATGAAACTG
GGCGAATATTTGGATTAATGCCACACCCTGAAAGAGCATTATATTCAACTAATGAACCTGAATTCCACCTTAAACGTGAA
ATTGCAAAAAGAAATGGTGAAATGCTTTCAAAATTTATTGAATGCAATATGCAAATATTTAAAAATGCTGTAAATTACTT
TAAAAAGTAA

Upstream 100 bases:

>100_bases
AAACATAAAAACGAAATAATAATAAATACGAGCCTTGAAAGAATGGAAGAAGTATATAAAAAGAGATTTAAGGACTTTTA
ATAATATTCTGGTGATAAAA

Downstream 100 bases:

>100_bases
TTTCGCTTTTTTCTTGCTTTTTTTCAAAATATTTACTAACATAACATCTTTTAACGTTTTTTAGAAATTTATAAATATTC
TCACCCATATAATTTAAATT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVPKVLIMSGYGINCEAETAHAFQLAGAKTDIVHINDLIAGKKKMKDYEIIMFPGGFSYGDDTGSGNAFANKIKNNLFED
LKEFIDSGKLILGICNGFQVMTNLGLFKIPDKNYGDRISALQSNLNNRYECRWVHIKENNSICIFTKGIDVLHVPIAHGE
GRFYCDIETFEKLKENNQIVFTYCNESGDFANLEYPLNPNGALYDIAGICDETGRIFGLMPHPERALYSTNEPEFHLKRE
IAKRNGEMLSKFIECNMQIFKNAVNYFKK

Sequences:

>Translated_269_residues
MVPKVLIMSGYGINCEAETAHAFQLAGAKTDIVHINDLIAGKKKMKDYEIIMFPGGFSYGDDTGSGNAFANKIKNNLFED
LKEFIDSGKLILGICNGFQVMTNLGLFKIPDKNYGDRISALQSNLNNRYECRWVHIKENNSICIFTKGIDVLHVPIAHGE
GRFYCDIETFEKLKENNQIVFTYCNESGDFANLEYPLNPNGALYDIAGICDETGRIFGLMPHPERALYSTNEPEFHLKRE
IAKRNGEMLSKFIECNMQIFKNAVNYFKK
>Mature_269_residues
MVPKVLIMSGYGINCEAETAHAFQLAGAKTDIVHINDLIAGKKKMKDYEIIMFPGGFSYGDDTGSGNAFANKIKNNLFED
LKEFIDSGKLILGICNGFQVMTNLGLFKIPDKNYGDRISALQSNLNNRYECRWVHIKENNSICIFTKGIDVLHVPIAHGE
GRFYCDIETFEKLKENNQIVFTYCNESGDFANLEYPLNPNGALYDIAGICDETGRIFGLMPHPERALYSTNEPEFHLKRE
IAKRNGEMLSKFIECNMQIFKNAVNYFKK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=241, Percent_Identity=31.9502074688797, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI48994899, Length=235, Percent_Identity=32.3404255319149, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17553022, Length=279, Percent_Identity=31.1827956989247, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=31.2236286919831, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582111, Length=231, Percent_Identity=37.6623376623377, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582109, Length=231, Percent_Identity=37.6623376623377, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17137292, Length=231, Percent_Identity=37.6623376623377, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 30441; Mature: 30441

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPKVLIMSGYGINCEAETAHAFQLAGAKTDIVHINDLIAGKKKMKDYEIIMFPGGFSYG
CCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCHHHCCCEEEEEECCCCCCC
DDTGSGNAFANKIKNNLFEDLKEFIDSGKLILGICNGFQVMTNLGLFKIPDKNYGDRISA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCEEECCCCCCCHHHHH
LQSNLNNRYECRWVHIKENNSICIFTKGIDVLHVPIAHGEGRFYCDIETFEKLKENNQIV
HHHCCCCCEEEEEEEEECCCCEEEEECCCEEEEEEEECCCCEEEEEHHHHHHHHCCCCEE
FTYCNESGDFANLEYPLNPNGALYDIAGICDETGRIFGLMPHPERALYSTNEPEFHLKRE
EEEECCCCCEEEEECCCCCCCCEEEECHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHH
IAKRNGEMLSKFIECNMQIFKNAVNYFKK
HHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVPKVLIMSGYGINCEAETAHAFQLAGAKTDIVHINDLIAGKKKMKDYEIIMFPGGFSYG
CCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCHHHCCCEEEEEECCCCCCC
DDTGSGNAFANKIKNNLFEDLKEFIDSGKLILGICNGFQVMTNLGLFKIPDKNYGDRISA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCEEECCCCCCCHHHHH
LQSNLNNRYECRWVHIKENNSICIFTKGIDVLHVPIAHGEGRFYCDIETFEKLKENNQIV
HHHCCCCCEEEEEEEEECCCCEEEEECCCEEEEEEEECCCCEEEEEHHHHHHHHCCCCEE
FTYCNESGDFANLEYPLNPNGALYDIAGICDETGRIFGLMPHPERALYSTNEPEFHLKRE
EEEECCCCCEEEEECCCCCCCCEEEECHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHH
IAKRNGEMLSKFIECNMQIFKNAVNYFKK
HHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA