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The map label for this gene is cofC

Identifier: 150399867

GI number: 150399867

Start: 1134376

End: 1135050

Strand: Reverse

Name: cofC

Synonym: Mevan_1122

Alternate gene names: 150399867

Gene position: 1135050-1134376 (Counterclockwise)

Preceding gene: 150399868

Following gene: 150399864

Centisome position: 65.99

GC content: 29.04

Gene sequence:

>675_bases
ATGTTAGCTGCATTAATTCCTGTATCGCCCCTTTCAAATGTAAAATCAAGATTAAAAGAATTTTTAAGTTCTAAAGAGCG
AATAGACTTAATTAAAAATATTTTGCTTGATACTTATGAAAAAGTAAAATCATGTGTGGATGCGTGCTACGTAGTAAGTA
AAGACGATGAAATACTTGAATTTTCAAAAAATCTTGGAATTATCCCAATAAAGGAGGATTTAAACACTAAAGGATTAAAT
GAAGCCATAGAATACTCTTTAAACATTATTAAAGAAGATTCCGTACTAATAACACCCGCAGATGTGCCCCTTTTAAAAGA
GGAAAATTTGGAATCAATTGTAAAAAAATCTGTGGAAAATTCGGTAATTATATGCCCTTCAAGGGGGGGCGGAACAAATT
TATTATTGTTAAACCCAAAAAACTGCATTAAGCCCCAATTTGAAGGATTTAGTTTTTTAAAACATATAAAAGAAGCTGAA
ATAAATAATTTAAATATAATAAAGTGTCATTCATTTTACACGTCAATTGATATAAATACTGTCGAGGACTTAGGTGAAAT
TTTTATTCATGGTAAAGATACTAAAACGTACAAATTTTTAAAAAACTTAAATATCGAAGCTTTTCCAAAGCATTCGTCTG
CTGGAAGATTTAATATCATTAGAAAAAGCCAGTAA

Upstream 100 bases:

>100_bases
ACTGGTGACTTAAGCGCTTTTGCAAATGCGATGTTATTTATATAATTCATGTGTGGATAATAACTAATAATTCGCCTTTT
TGGCATTTAGTCGTGGTAAA

Downstream 100 bases:

>100_bases
TTTAAAAATTAGATAAAAGATGAAATAAAATTAAGGCCTAAGTCCCCCAATATTAAGTCCTTCTTTTTCGTCAAAGCCCA
TTAAGATATTCATATTTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLAALIPVSPLSNVKSRLKEFLSSKERIDLIKNILLDTYEKVKSCVDACYVVSKDDEILEFSKNLGIIPIKEDLNTKGLN
EAIEYSLNIIKEDSVLITPADVPLLKEENLESIVKKSVENSVIICPSRGGGTNLLLLNPKNCIKPQFEGFSFLKHIKEAE
INNLNIIKCHSFYTSIDINTVEDLGEIFIHGKDTKTYKFLKNLNIEAFPKHSSAGRFNIIRKSQ

Sequences:

>Translated_224_residues
MLAALIPVSPLSNVKSRLKEFLSSKERIDLIKNILLDTYEKVKSCVDACYVVSKDDEILEFSKNLGIIPIKEDLNTKGLN
EAIEYSLNIIKEDSVLITPADVPLLKEENLESIVKKSVENSVIICPSRGGGTNLLLLNPKNCIKPQFEGFSFLKHIKEAE
INNLNIIKCHSFYTSIDINTVEDLGEIFIHGKDTKTYKFLKNLNIEAFPKHSSAGRFNIIRKSQ
>Mature_224_residues
MLAALIPVSPLSNVKSRLKEFLSSKERIDLIKNILLDTYEKVKSCVDACYVVSKDDEILEFSKNLGIIPIKEDLNTKGLN
EAIEYSLNIIKEDSVLITPADVPLLKEENLESIVKKSVENSVIICPSRGGGTNLLLLNPKNCIKPQFEGFSFLKHIKEAE
INNLNIIKCHSFYTSIDINTVEDLGEIFIHGKDTKTYKFLKNLNIEAFPKHSSAGRFNIIRKSQ

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_METVS (A6URA0)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323634.1
- ProteinModelPortal:   A6URA0
- SMR:   A6URA0
- STRING:   A6URA0
- GeneID:   5326069
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_1122
- eggNOG:   arNOG08928
- HOGENOM:   HBG699055
- OMA:   SSAGRFN
- ProtClustDB:   CLSK876373
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 25210; Mature: 25210

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALIPVSPLSNVKSRLKEFLSSKERIDLIKNILLDTYEKVKSCVDACYVVSKDDEILE
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHH
FSKNLGIIPIKEDLNTKGLNEAIEYSLNIIKEDSVLITPADVPLLKEENLESIVKKSVEN
HHHCCCEEEECCCCCCCCHHHHHHHHHHEEECCCEEEECCCCCCCCCCCHHHHHHHHCCC
SVIICPSRGGGTNLLLLNPKNCIKPQFEGFSFLKHIKEAEINNLNIIKCHSFYTSIDINT
CEEEEECCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECEEEEECCCH
VEDLGEIFIHGKDTKTYKFLKNLNIEAFPKHSSAGRFNIIRKSQ
HHHHHHEEECCCCCHHHHHHHHCCCEECCCCCCCCEEEEEECCC
>Mature Secondary Structure
MLAALIPVSPLSNVKSRLKEFLSSKERIDLIKNILLDTYEKVKSCVDACYVVSKDDEILE
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHH
FSKNLGIIPIKEDLNTKGLNEAIEYSLNIIKEDSVLITPADVPLLKEENLESIVKKSVEN
HHHCCCEEEECCCCCCCCHHHHHHHHHHEEECCCEEEECCCCCCCCCCCHHHHHHHHCCC
SVIICPSRGGGTNLLLLNPKNCIKPQFEGFSFLKHIKEAEINNLNIIKCHSFYTSIDINT
CEEEEECCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECEEEEECCCH
VEDLGEIFIHGKDTKTYKFLKNLNIEAFPKHSSAGRFNIIRKSQ
HHHHHHEEECCCCCHHHHHHHHCCCEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA