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The map label for this gene is comE [H]

Identifier: 150399739

GI number: 150399739

Start: 1006957

End: 1007523

Strand: Reverse

Name: comE [H]

Synonym: Mevan_0991

Alternate gene names: 150399739

Gene position: 1007523-1006957 (Counterclockwise)

Preceding gene: 150399740

Following gene: 150399735

Centisome position: 58.58

GC content: 31.04

Gene sequence:

>567_bases
ATGGAATTTGAACTTACAAGATATGACGCAATTAAAATTTTAATGGAATATGTAACCGATGAAATAGTCGTTTGTAACAT
CGGAATTCCAAGTAAAGAACTCTTTAAAATAAAGGATAGGGAAAAAAACTTCTACATGTTAGGATCGATGGGTTTGTCAT
CATCTATCGGACATGGAATTTCACTTTCAATAGAAAAAAAGGTAATTGCAATTGATGGTGATGGTTCAGTTTTGATGAAC
ATGGGTTCTCTTGCAACAATTGGAAAAACGACAGAAAAAAACTTTTTACTATTTATTGTAGATAATTGTGCATACGGTTC
AACTGGAAACCAAAAAACACACAGTTCATGCACTGATTTATACCAAGTTTCAAAAGCATGCGCAATTGATTCGATATTAG
TTATAAATGAAATTGAGCTAAGGAACGCTTTAAAAAAAGTTTTAAACGAACGTGGCACAAATGTAATTTTAGTAAAAGCA
AGGGCACACAATGAAAACGTTCCAAATATAACACTTGTTCCAACTGAAATAAAGCACAGATTTATGAATTCATTAAAAAA
AGAATAA

Upstream 100 bases:

>100_bases
ATATTAAATGATATTGGAGTTTTTGGAGTTTTAATTGGAACCACAATTCACAATGGAACGCTTGATTTAAAAAAAATCAT
TCAAAAATATGGGGAATAGT

Downstream 100 bases:

>100_bases
TTAAGTAAATCTAAATTTTAAATTTTATTCTTAAAACTTAAAATGTTTTCAAAATCTTGTATTATTGGATAACCTATTAA
TATGTGGTCTTTAAATCTAT

Product: thiamine pyrophosphate binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEFELTRYDAIKILMEYVTDEIVVCNIGIPSKELFKIKDREKNFYMLGSMGLSSSIGHGISLSIEKKVIAIDGDGSVLMN
MGSLATIGKTTEKNFLLFIVDNCAYGSTGNQKTHSSCTDLYQVSKACAIDSILVINEIELRNALKKVLNERGTNVILVKA
RAHNENVPNITLVPTEIKHRFMNSLKKE

Sequences:

>Translated_188_residues
MEFELTRYDAIKILMEYVTDEIVVCNIGIPSKELFKIKDREKNFYMLGSMGLSSSIGHGISLSIEKKVIAIDGDGSVLMN
MGSLATIGKTTEKNFLLFIVDNCAYGSTGNQKTHSSCTDLYQVSKACAIDSILVINEIELRNALKKVLNERGTNVILVKA
RAHNENVPNITLVPTEIKHRFMNSLKKE
>Mature_188_residues
MEFELTRYDAIKILMEYVTDEIVVCNIGIPSKELFKIKDREKNFYMLGSMGLSSSIGHGISLSIEKKVIAIDGDGSVLMN
MGSLATIGKTTEKNFLLFIVDNCAYGSTGNQKTHSSCTDLYQVSKACAIDSILVINEIELRNALKKVLNERGTNVILVKA
RAHNENVPNITLVPTEIKHRFMNSLKKE

Specific function: Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde [H]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022494
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C [H]

EC number: =4.1.1.79 [H]

Molecular weight: Translated: 20918; Mature: 20918

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFELTRYDAIKILMEYVTDEIVVCNIGIPSKELFKIKDREKNFYMLGSMGLSSSIGHGI
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHEEEECCCCCEEEEECCCCCCCCCCCE
SLSIEKKVIAIDGDGSVLMNMGSLATIGKTTEKNFLLFIVDNCAYGSTGNQKTHSSCTDL
EEEEEEEEEEECCCCCEEEECCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
YQVSKACAIDSILVINEIELRNALKKVLNERGTNVILVKARAHNENVPNITLVPTEIKHR
HHHHHHHHHCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEHHHHHHH
FMNSLKKE
HHHHHCCC
>Mature Secondary Structure
MEFELTRYDAIKILMEYVTDEIVVCNIGIPSKELFKIKDREKNFYMLGSMGLSSSIGHGI
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHEEEECCCCCEEEEECCCCCCCCCCCE
SLSIEKKVIAIDGDGSVLMNMGSLATIGKTTEKNFLLFIVDNCAYGSTGNQKTHSSCTDL
EEEEEEEEEEECCCCCEEEECCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
YQVSKACAIDSILVINEIELRNALKKVLNERGTNVILVKARAHNENVPNITLVPTEIKHR
HHHHHHHHHCEEEEEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEHHHHHHH
FMNSLKKE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10940029 [H]