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The map label for this gene is bioD

Identifier: 150399635

GI number: 150399635

Start: 906266

End: 906901

Strand: Reverse

Name: bioD

Synonym: Mevan_0885

Alternate gene names: 150399635

Gene position: 906901-906266 (Counterclockwise)

Preceding gene: 150399636

Following gene: 150399634

Centisome position: 52.73

GC content: 28.93

Gene sequence:

>636_bases
ATGATATTTGTTACTGGAACTGATACGGGAATTGGAAAAACATACGTTTCAGCCATTTTAGGGAAAATTTTAAAAGAAAA
AGGAATAAATGTAGGTTACATGAAGCCAGTTGAATCTGGAGGTATTGAAGATACTGCTTATGTTAGGTCTGAACTTGGAC
TTAATAATTCTTTCGAGGAATTAAATCCAGTAAACCTAAAAAAACCACTTTCACCAAATATTTCTGCAAAAATTGAAGAA
AAAGAAATAGATATTTTGAAAATAAAAGCTGCTTTTGAAAAATTAAAAGAAGAATACGAATTTTTAATTGTCGAAGGTGC
AGGTGGAGTTGCAGTCCCTATAAAAAAAGACTTTTTAATCGCAGATTTGATAAAATACCTAGATTTGACGTGCATAGTTG
TTTCAAGACCAAATCTTGGAACGATAAATCACACAATTTTAACTGTTGATTTTTTGCGGAAAAAGGGAATAACTGTTTTA
GGAGTAATAATAAACTGTATTACAGATGTTTCAAAAGTGCCATATTATGAAGAAACCTTCAAATCGATTGAAGAATTTGG
AAATGTTGAAATTATTGGTATTGTCAATGATAAAAAAGATTTTTATATAGACTTAAAAAAACTAAATTTACCTTAA

Upstream 100 bases:

>100_bases
ATTAGTATAACTTCAAAACACGAAAAAAACGATTTTAAATACCTTTGCGAAAAAATAGACAAATTAACAATTTAAATATG
GCAAATTTTCGAGGGTTAAA

Downstream 100 bases:

>100_bases
TAATACGGTGATTTTTTGAAAGGTATGATTTTAGAGATATTTTATACATCGCTAATTAGTACTTTAAAAATATCTTTAGT
TGTGCTTTCAACGATATATA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIFVTGTDTGIGKTYVSAILGKILKEKGINVGYMKPVESGGIEDTAYVRSELGLNNSFEELNPVNLKKPLSPNISAKIEE
KEIDILKIKAAFEKLKEEYEFLIVEGAGGVAVPIKKDFLIADLIKYLDLTCIVVSRPNLGTINHTILTVDFLRKKGITVL
GVIINCITDVSKVPYYEETFKSIEEFGNVEIIGIVNDKKDFYIDLKKLNLP

Sequences:

>Translated_211_residues
MIFVTGTDTGIGKTYVSAILGKILKEKGINVGYMKPVESGGIEDTAYVRSELGLNNSFEELNPVNLKKPLSPNISAKIEE
KEIDILKIKAAFEKLKEEYEFLIVEGAGGVAVPIKKDFLIADLIKYLDLTCIVVSRPNLGTINHTILTVDFLRKKGITVL
GVIINCITDVSKVPYYEETFKSIEEFGNVEIIGIVNDKKDFYIDLKKLNLP
>Mature_211_residues
MIFVTGTDTGIGKTYVSAILGKILKEKGINVGYMKPVESGGIEDTAYVRSELGLNNSFEELNPVNLKKPLSPNISAKIEE
KEIDILKIKAAFEKLKEEYEFLIVEGAGGVAVPIKKDFLIADLIKYLDLTCIVVSRPNLGTINHTILTVDFLRKKGITVL
GVIINCITDVSKVPYYEETFKSIEEFGNVEIIGIVNDKKDFYIDLKKLNLP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family

Homologues:

Organism=Escherichia coli, GI1786995, Length=178, Percent_Identity=33.7078651685393, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081944, Length=173, Percent_Identity=28.3236994219653, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324385, Length=180, Percent_Identity=36.6666666666667, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOD_METVS (A6UQL8)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323402.1
- ProteinModelPortal:   A6UQL8
- SMR:   A6UQL8
- STRING:   A6UQL8
- GeneID:   5326214
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0885
- eggNOG:   arNOG09163
- HOGENOM:   HBG650065
- OMA:   LNNYNHE
- ProtClustDB:   CLSK876518
- HAMAP:   MF_00336
- InterPro:   IPR004472
- InterPro:   IPR002586
- PIRSF:   PIRSF006755
- TIGRFAMs:   TIGR00347

Pfam domain/function: PF01656 CbiA

EC number: =6.3.3.3

Molecular weight: Translated: 23416; Mature: 23416

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVTGTDTGIGKTYVSAILGKILKEKGINVGYMKPVESGGIEDTAYVRSELGLNNSFEE
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCHHH
LNPVNLKKPLSPNISAKIEEKEIDILKIKAAFEKLKEEYEFLIVEGAGGVAVPIKKDFLI
CCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCEEEEEEECCCCEEECCCHHHHH
ADLIKYLDLTCIVVSRPNLGTINHTILTVDFLRKKGITVLGVIINCITDVSKVPYYEETF
HHHHHHHCEEEEEEECCCCCCCCHHEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
KSIEEFGNVEIIGIVNDKKDFYIDLKKLNLP
HHHHHHCCEEEEEEEECCCEEEEEEEECCCC
>Mature Secondary Structure
MIFVTGTDTGIGKTYVSAILGKILKEKGINVGYMKPVESGGIEDTAYVRSELGLNNSFEE
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCHHH
LNPVNLKKPLSPNISAKIEEKEIDILKIKAAFEKLKEEYEFLIVEGAGGVAVPIKKDFLI
CCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCEEEEEEECCCCEEECCCHHHHH
ADLIKYLDLTCIVVSRPNLGTINHTILTVDFLRKKGITVLGVIINCITDVSKVPYYEETF
HHHHHHHCEEEEEEECCCCCCCCHHEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
KSIEEFGNVEIIGIVNDKKDFYIDLKKLNLP
HHHHHHCCEEEEEEEECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA