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The map label for this gene is alr [H]

Identifier: 150399575

GI number: 150399575

Start: 853380

End: 854522

Strand: Reverse

Name: alr [H]

Synonym: Mevan_0824

Alternate gene names: 150399575

Gene position: 854522-853380 (Counterclockwise)

Preceding gene: 150399576

Following gene: 150399574

Centisome position: 49.68

GC content: 31.58

Gene sequence:

>1143_bases
ATGATTTCACATCCAATATGGGCTGAAATTGATTTAAATGCAGTTAAAAATAATATTAAAGAAATAAGGAGAATTACAAA
CTCGGATTCCCAGATAATGGCAGTAGTAAAAGCAAATGCTTATGGACACGGGGCAGTTGAAATTTCAAAAGTAGTTTTAA
AAAACGGTGCCGATAGGCTTGCTGTTGCAAGATCAAAAGAAGCTATTGAATTAAGAAATGCAGGATTTAAATGCCCTATT
TTAGTCTTTGGATATAATACAATAGAAGAAATTTTGGAACTGATTAAAAACGATGTTATATTAACAGTTTATTCTATTGA
AATTGCAAAAGACATTCAAAAGATTGCAAAAGACATTCAAAAGATTGCAAAAGACATTCAAAAGATTGCAAAAGTACATT
TAAAGATAGATACCGGAATGAATAGACTTGGATTTATTCCCGATAAAAAGACTATTAATGAAATATTGAAAATTAGTGAA
TTTTTAAATATCGAAATTGAGGGAATATATACACATTTTGCAGATGCGGATAATTCTGATAAAACGTATACAAAAAAGCA
ATTTTCAAAATTTATGGAATTTTTGACTGATTTAGAAGATTCGGGAATTAATATTCCAATAAAGCATGTATCAAACAGTG
CAGCAATAATTGATCATCCGGAAACTCATTTAAACATGGTAAGGCCGGGAATTATTCTTTATGGGCTTTATCCATCGGAA
TTAGTCCAAAAAGATAAGATTAATTTAGAGCCCGTTATGAGCTTAAAGTGCTTGATTACACACGTAAAAGACGTTCCAAG
GGGAACAAAAATAAGCTATGGCTGTACATATATTACCAAAAAAAAATCAAAAATTGCATCTATTCCCTTAGGTTATGCGG
ATGGATTTACAAGGATGTTAAAGAATGGAAAAGTCCTAGTTGGTGGAAAAAGGGCGCCAATTGTTGGACGGATATGTATG
GATCAGTGTATGGCGGATGTTTCCAATATAGATGACGTAAAAATTGGCGATACAGTACTTGTTTTTGGAAAACATGAAAA
GTATACTGTTCCAGTAGAAGAAATTTCAAACGAACTAAAAACTATAAATTATGAACTGGTCTGCATGATTTCTAACCGCG
TTCCAAGAGTATATAGATATTAA

Upstream 100 bases:

>100_bases
GCACATAACCTTCCATACACACCAGTAGAAAAAGCTTTAAATGAATAATTCTCTTATTTTTGATATAACTTACCTAGGTA
ACTTTTTTCAGGTGAATTTA

Downstream 100 bases:

>100_bases
TTTTTTAACACATATATTTAAATATAATAATATTTTTATACTTTTATAACGGAATATATATTCCGGTAGTATATATAATT
CAATAATGCCATACATAAAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MISHPIWAEIDLNAVKNNIKEIRRITNSDSQIMAVVKANAYGHGAVEISKVVLKNGADRLAVARSKEAIELRNAGFKCPI
LVFGYNTIEEILELIKNDVILTVYSIEIAKDIQKIAKDIQKIAKDIQKIAKVHLKIDTGMNRLGFIPDKKTINEILKISE
FLNIEIEGIYTHFADADNSDKTYTKKQFSKFMEFLTDLEDSGINIPIKHVSNSAAIIDHPETHLNMVRPGIILYGLYPSE
LVQKDKINLEPVMSLKCLITHVKDVPRGTKISYGCTYITKKKSKIASIPLGYADGFTRMLKNGKVLVGGKRAPIVGRICM
DQCMADVSNIDDVKIGDTVLVFGKHEKYTVPVEEISNELKTINYELVCMISNRVPRVYRY

Sequences:

>Translated_380_residues
MISHPIWAEIDLNAVKNNIKEIRRITNSDSQIMAVVKANAYGHGAVEISKVVLKNGADRLAVARSKEAIELRNAGFKCPI
LVFGYNTIEEILELIKNDVILTVYSIEIAKDIQKIAKDIQKIAKDIQKIAKVHLKIDTGMNRLGFIPDKKTINEILKISE
FLNIEIEGIYTHFADADNSDKTYTKKQFSKFMEFLTDLEDSGINIPIKHVSNSAAIIDHPETHLNMVRPGIILYGLYPSE
LVQKDKINLEPVMSLKCLITHVKDVPRGTKISYGCTYITKKKSKIASIPLGYADGFTRMLKNGKVLVGGKRAPIVGRICM
DQCMADVSNIDDVKIGDTVLVFGKHEKYTVPVEEISNELKTINYELVCMISNRVPRVYRY
>Mature_380_residues
MISHPIWAEIDLNAVKNNIKEIRRITNSDSQIMAVVKANAYGHGAVEISKVVLKNGADRLAVARSKEAIELRNAGFKCPI
LVFGYNTIEEILELIKNDVILTVYSIEIAKDIQKIAKDIQKIAKDIQKIAKVHLKIDTGMNRLGFIPDKKTINEILKISE
FLNIEIEGIYTHFADADNSDKTYTKKQFSKFMEFLTDLEDSGINIPIKHVSNSAAIIDHPETHLNMVRPGIILYGLYPSE
LVQKDKINLEPVMSLKCLITHVKDVPRGTKISYGCTYITKKKSKIASIPLGYADGFTRMLKNGKVLVGGKRAPIVGRICM
DQCMADVSNIDDVKIGDTVLVFGKHEKYTVPVEEISNELKTINYELVCMISNRVPRVYRY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=379, Percent_Identity=31.6622691292876, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1790487, Length=377, Percent_Identity=30.2387267904509, Blast_Score=181, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42709; Mature: 42709

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHPIWAEIDLNAVKNNIKEIRRITNSDSQIMAVVKANAYGHGAVEISKVVLKNGADRL
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCE
AVARSKEAIELRNAGFKCPILVFGYNTIEEILELIKNDVILTVYSIEIAKDIQKIAKDIQ
EHHCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHH
KIAKDIQKIAKVHLKIDTGMNRLGFIPDKKTINEILKISEFLNIEIEGIYTHFADADNSD
HHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCC
KTYTKKQFSKFMEFLTDLEDSGINIPIKHVSNSAAIIDHPETHLNMVRPGIILYGLYPSE
CHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCEEEEECCHHH
LVQKDKINLEPVMSLKCLITHVKDVPRGTKISYGCTYITKKKSKIASIPLGYADGFTRML
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECEEEEEECCCHHCCCCCCHHHHHHHHH
KNGKVLVGGKRAPIVGRICMDQCMADVSNIDDVKIGDTVLVFGKHEKYTVPVEEISNELK
HCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCEEECHHHHHHHHH
TINYELVCMISNRVPRVYRY
CCCEEEEEEECCCCCHHCCC
>Mature Secondary Structure
MISHPIWAEIDLNAVKNNIKEIRRITNSDSQIMAVVKANAYGHGAVEISKVVLKNGADRL
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCE
AVARSKEAIELRNAGFKCPILVFGYNTIEEILELIKNDVILTVYSIEIAKDIQKIAKDIQ
EHHCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHH
KIAKDIQKIAKVHLKIDTGMNRLGFIPDKKTINEILKISEFLNIEIEGIYTHFADADNSD
HHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCC
KTYTKKQFSKFMEFLTDLEDSGINIPIKHVSNSAAIIDHPETHLNMVRPGIILYGLYPSE
CHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCEEEEECCHHH
LVQKDKINLEPVMSLKCLITHVKDVPRGTKISYGCTYITKKKSKIASIPLGYADGFTRML
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECEEEEEECCCHHCCCCCCHHHHHHHHH
KNGKVLVGGKRAPIVGRICMDQCMADVSNIDDVKIGDTVLVFGKHEKYTVPVEEISNELK
HCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCEEECHHHHHHHHH
TINYELVCMISNRVPRVYRY
CCCEEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA