Click here to switch to the map view.

The map label for this gene is purO

Identifier: 150399371

GI number: 150399371

Start: 676017

End: 676622

Strand: Reverse

Name: purO

Synonym: Mevan_0620

Alternate gene names: 150399371

Gene position: 676622-676017 (Counterclockwise)

Preceding gene: 150399372

Following gene: 150399370

Centisome position: 39.34

GC content: 31.52

Gene sequence:

>606_bases
ATGTACATTGGTAGATTTTTAGTTTTGGGAAAAACCTTAAATGGGAAGCCGTTTGTAACATACCGGGTTTCAAGTAGGAG
TTTTCCAAACCGGATTGCAAAAATAATGAACGACGAAACAGTTGCAATTTTACCTAAAAACTTAGAAGAAATGTTTAAAA
ACCCATATATTACATATAATTGTGTAAAAATTGTAGGAAATATTGCAGTAGTTACCAATGGTTCGCATACTGACATAATC
GCAGATAAAATTAGAATTGGTCTTCCTATACGAGATGCTTTATCGTATTCATTATTAACAATGGACTATGAAAAGGATGA
TTTTAATACTCCAAGAATTGCAGCGGTTTTAACTGACAATGAAGCCTACATGGGTTATGTTTCAGATAATGATATCCGGA
TTAAAAAAGTAGAGCTTGAAGAAGGTTATGCATATTACTTAAGTACTTATGAAGCGTGTAAAATTACAGAACATCAAAAA
ATTGAAGTTTCTAAAAATACGCCTGAAGACCTCTGTAAATTTATAATGGAACATAACGAATTTGAAAAGCCAGTAACTTC
CACAACTGTTTTAATGGATTCTGGATTTAAAATTGCAACTCTTTAA

Upstream 100 bases:

>100_bases
GCGGACTTTGTGTAAGTTACTGTCCATTAAATGCAATTAAAAATTAGAATCTCCCTTTAAAAATGGATAAAGTTATAAAA
ATATTAATTCAGGTGGTTTT

Downstream 100 bases:

>100_bases
GTTATAAGTACTTTATCTACTTTATAATTAAATTATAACTATTTTAATCTTATTTTAAATATATGCGGTGTAATTTTTGA
AAATTTATAGCAATTCTCGA

Product: IMP cyclohydrolase

Products: NA

Alternate protein names: IMP synthase; Inosinicase

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MYIGRFLVLGKTLNGKPFVTYRVSSRSFPNRIAKIMNDETVAILPKNLEEMFKNPYITYNCVKIVGNIAVVTNGSHTDII
ADKIRIGLPIRDALSYSLLTMDYEKDDFNTPRIAAVLTDNEAYMGYVSDNDIRIKKVELEEGYAYYLSTYEACKITEHQK
IEVSKNTPEDLCKFIMEHNEFEKPVTSTTVLMDSGFKIATL

Sequences:

>Translated_201_residues
MYIGRFLVLGKTLNGKPFVTYRVSSRSFPNRIAKIMNDETVAILPKNLEEMFKNPYITYNCVKIVGNIAVVTNGSHTDII
ADKIRIGLPIRDALSYSLLTMDYEKDDFNTPRIAAVLTDNEAYMGYVSDNDIRIKKVELEEGYAYYLSTYEACKITEHQK
IEVSKNTPEDLCKFIMEHNEFEKPVTSTTVLMDSGFKIATL
>Mature_201_residues
MYIGRFLVLGKTLNGKPFVTYRVSSRSFPNRIAKIMNDETVAILPKNLEEMFKNPYITYNCVKIVGNIAVVTNGSHTDII
ADKIRIGLPIRDALSYSLLTMDYEKDDFNTPRIAAVLTDNEAYMGYVSDNDIRIKKVELEEGYAYYLSTYEACKITEHQK
IEVSKNTPEDLCKFIMEHNEFEKPVTSTTVLMDSGFKIATL

Specific function: Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP

COG id: COG3363

COG function: function code F; Archaeal IMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal IMP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURO_METVS (A6UPV4)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323138.1
- ProteinModelPortal:   A6UPV4
- SMR:   A6UPV4
- STRING:   A6UPV4
- GeneID:   5325073
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0620
- eggNOG:   arNOG08037
- HOGENOM:   HBG539724
- OMA:   YIGRFLV
- ProtClustDB:   PRK04151
- HAMAP:   MF_00705
- InterPro:   IPR010191
- InterPro:   IPR020600
- Gene3D:   G3DSA:3.60.20.20
- PIRSF:   PIRSF004866
- TIGRFAMs:   TIGR01922

Pfam domain/function: PF07826 IMP_cyclohyd; SSF75569 PurO_cyclohydro

EC number: =3.5.4.10

Molecular weight: Translated: 22906; Mature: 22906

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGRFLVLGKTLNGKPFVTYRVSSRSFPNRIAKIMNDETVAILPKNLEEMFKNPYITYN
CCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHCCCCEEEE
CVKIVGNIAVVTNGSHTDIIADKIRIGLPIRDALSYSLLTMDYEKDDFNTPRIAAVLTDN
EEEEECCEEEEECCCCCCEEEEEEEECCCHHHHHCEEEEEEECCCCCCCCCEEEEEEECC
EAYMGYVSDNDIRIKKVELEEGYAYYLSTYEACKITEHQKIEVSKNTPEDLCKFIMEHNE
CEEEEEEECCCEEEEEEEECCCEEEEEECCCEEECCCCCEEEECCCCHHHHHHHHHHCCC
FEKPVTSTTVLMDSGFKIATL
CCCCCCEEEEEEECCEEEEEC
>Mature Secondary Structure
MYIGRFLVLGKTLNGKPFVTYRVSSRSFPNRIAKIMNDETVAILPKNLEEMFKNPYITYN
CCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHCCCCEEEE
CVKIVGNIAVVTNGSHTDIIADKIRIGLPIRDALSYSLLTMDYEKDDFNTPRIAAVLTDN
EEEEECCEEEEECCCCCCEEEEEEEECCCHHHHHCEEEEEEECCCCCCCCCEEEEEEECC
EAYMGYVSDNDIRIKKVELEEGYAYYLSTYEACKITEHQKIEVSKNTPEDLCKFIMEHNE
CEEEEEEECCCEEEEEEEECCCEEEEEECCCEEECCCCCEEEECCCCHHHHHHHHHHCCC
FEKPVTSTTVLMDSGFKIATL
CCCCCCEEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA