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The map label for this gene is ygbD [C]

Identifier: 150399324

GI number: 150399324

Start: 622325

End: 623653

Strand: Reverse

Name: ygbD [C]

Synonym: Mevan_0572

Alternate gene names: 150399324

Gene position: 623653-622325 (Counterclockwise)

Preceding gene: 150399325

Following gene: 150399323

Centisome position: 36.26

GC content: 35.97

Gene sequence:

>1329_bases
ATGAATGTCGTAATCATTGGAAGCGGTGCTGGAGGACTTACTACTGCATCAAATATAAAAAAATATAGTGCTAATGCTAA
AATTACTATATTAACGGAGGATAAACATATTGCATATTCCCCATGTGCAATACCTTATGTTATTGGTGGAGAAATTGAAA
AATTTGAAAATATAGTAATGCACACTCCAAAAGACTACGAAAGAAAGGGAATTGAAGTTATTACTGAATCCAAAGTAGTT
GATGTAGTAGCTAACCAAAATATAGTAATTTATGAAGAAAAAGGAATTAAAAAAGAAATTTCCTATGAAAAATTAGTAAT
CGCAACAGGTGGAACTCCATTTATTCCACCAATAGATGGCGTAAATTTAAAAGGGGTATTTAAGGTAAGAACAATTGAAG
ACGGCCAAAGCATAAAAGAATGGACAAAAACTACAAAACAAGCAGTAGTTGCAGGAGCAGGGGCAATCGGCTTAGAAATG
GCATTTGGATTGAAAGAAATTGGAATAGATGTAACTGTTGTTGAAATGGTTCCACAGGTGTTTCCAAGGGCTCTTGACCC
AGAAATGGCAAAAATAGTTCAGGAGTATCTTGAAGAAAATGGAATAAGAATTATTTTAGAAAAACCACTCGGAAAAATTA
TTGGAAATGAAAAAGTTAAGGCAGTAATTATCGGGGAAGAACAAATTGATACAGAGCTTGTAATAATGTCAACAGGCGTT
CGTTCAAACATTGAACTTGCTAAACTAGCAGGCTGTGAGATTGGGCGATGGGCAATACTTACAAATAACTTGATGCAGAC
TTCAATTGAGAACATATATGCAGTTGGTGACTGTGTTGAAGTAATTGATGCAATAACTGGCCAAAATACTCTTTCACCAT
TTGGAACAACTGCTGTAAGGCAGGGGAAAGTTGCAGCAAAAAGCATTGCAGGAATTGATGCAGAAAGTAGTCCGGTACTA
AACAGCATGGTTTCAAAAATTGGCGCCCTTGAAATTGGTGGAACAGGTATGACAGAAACTGCTGCAAAAATGAATGGAAT
AGATGTGGTTATCGGTAACGCAAAAGCACTTACAAGGGCAAGGTATTATCCGGGTGGTGAACCAATATTTATAAAACTGG
TATGTGAAAAAAATTCAAGAAGGATTATCGGATGCCAGATTATTTCAAAAGAACGAGTTGCAGAACGAGTTGACGCAATG
TCTATTGCAATTTCAAAGAAAATGACGGTTGACGAACTTTTAAATCAAGAATTTAGTTATGCGCCTCCTGTTTCAATGGT
AATTGACCCGTTAACTTTTGCAGCAGAGGATGCATTTGAAAAGTTTTAA

Upstream 100 bases:

>100_bases
TCGTATTATCAATTAAATTTATATATCTGAAAAAAGTTCCTATATTTAAAAACTATATTTTAATTTAACTGAATATTTTT
ATTTTACTACTGGTGAAAAA

Downstream 100 bases:

>100_bases
TCTTAAACTACTAAATTAAAAAAGTAACTATTTTTAAATCTTTTAAAACTAAAAACAAAATTTATTATACTATAGTAATA
CAAGCTTTTAAATTTGTATT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNVVIIGSGAGGLTTASNIKKYSANAKITILTEDKHIAYSPCAIPYVIGGEIEKFENIVMHTPKDYERKGIEVITESKVV
DVVANQNIVIYEEKGIKKEISYEKLVIATGGTPFIPPIDGVNLKGVFKVRTIEDGQSIKEWTKTTKQAVVAGAGAIGLEM
AFGLKEIGIDVTVVEMVPQVFPRALDPEMAKIVQEYLEENGIRIILEKPLGKIIGNEKVKAVIIGEEQIDTELVIMSTGV
RSNIELAKLAGCEIGRWAILTNNLMQTSIENIYAVGDCVEVIDAITGQNTLSPFGTTAVRQGKVAAKSIAGIDAESSPVL
NSMVSKIGALEIGGTGMTETAAKMNGIDVVIGNAKALTRARYYPGGEPIFIKLVCEKNSRRIIGCQIISKERVAERVDAM
SIAISKKMTVDELLNQEFSYAPPVSMVIDPLTFAAEDAFEKF

Sequences:

>Translated_442_residues
MNVVIIGSGAGGLTTASNIKKYSANAKITILTEDKHIAYSPCAIPYVIGGEIEKFENIVMHTPKDYERKGIEVITESKVV
DVVANQNIVIYEEKGIKKEISYEKLVIATGGTPFIPPIDGVNLKGVFKVRTIEDGQSIKEWTKTTKQAVVAGAGAIGLEM
AFGLKEIGIDVTVVEMVPQVFPRALDPEMAKIVQEYLEENGIRIILEKPLGKIIGNEKVKAVIIGEEQIDTELVIMSTGV
RSNIELAKLAGCEIGRWAILTNNLMQTSIENIYAVGDCVEVIDAITGQNTLSPFGTTAVRQGKVAAKSIAGIDAESSPVL
NSMVSKIGALEIGGTGMTETAAKMNGIDVVIGNAKALTRARYYPGGEPIFIKLVCEKNSRRIIGCQIISKERVAERVDAM
SIAISKKMTVDELLNQEFSYAPPVSMVIDPLTFAAEDAFEKF
>Mature_442_residues
MNVVIIGSGAGGLTTASNIKKYSANAKITILTEDKHIAYSPCAIPYVIGGEIEKFENIVMHTPKDYERKGIEVITESKVV
DVVANQNIVIYEEKGIKKEISYEKLVIATGGTPFIPPIDGVNLKGVFKVRTIEDGQSIKEWTKTTKQAVVAGAGAIGLEM
AFGLKEIGIDVTVVEMVPQVFPRALDPEMAKIVQEYLEENGIRIILEKPLGKIIGNEKVKAVIIGEEQIDTELVIMSTGV
RSNIELAKLAGCEIGRWAILTNNLMQTSIENIYAVGDCVEVIDAITGQNTLSPFGTTAVRQGKVAAKSIAGIDAESSPVL
NSMVSKIGALEIGGTGMTETAAKMNGIDVVIGNAKALTRARYYPGGEPIFIKLVCEKNSRRIIGCQIISKERVAERVDAM
SIAISKKMTVDELLNQEFSYAPPVSMVIDPLTFAAEDAFEKF

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=376, Percent_Identity=27.6595744680851, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI21389617, Length=376, Percent_Identity=27.6595744680851, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI65787454, Length=376, Percent_Identity=27.6595744680851, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI22202629, Length=262, Percent_Identity=26.7175572519084, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4757732, Length=296, Percent_Identity=25.3378378378378, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789065, Length=333, Percent_Identity=26.7267267267267, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789765, Length=342, Percent_Identity=28.3625730994152, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1788892, Length=276, Percent_Identity=21.0144927536232, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082354, Length=366, Percent_Identity=23.224043715847, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=362, Percent_Identity=24.3093922651934, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32565766, Length=281, Percent_Identity=26.6903914590747, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24585130, Length=316, Percent_Identity=24.0506329113924, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639257, Length=315, Percent_Identity=24.1269841269841, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281359715, Length=280, Percent_Identity=24.6428571428571, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281359713, Length=280, Percent_Identity=24.6428571428571, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639250, Length=280, Percent_Identity=24.6428571428571, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18543267, Length=280, Percent_Identity=24.6428571428571, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639252, Length=280, Percent_Identity=24.6428571428571, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640553, Length=353, Percent_Identity=27.7620396600567, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640549, Length=353, Percent_Identity=27.7620396600567, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640551, Length=353, Percent_Identity=27.7620396600567, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47698; Mature: 47698

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVIIGSGAGGLTTASNIKKYSANAKITILTEDKHIAYSPCAIPYVIGGEIEKFENIVM
CEEEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEECCCHHHHHHHHC
HTPKDYERKGIEVITESKVVDVVANQNIVIYEEKGIKKEISYEKLVIATGGTPFIPPIDG
CCCCCHHCCCCEEEECCEEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
VNLKGVFKVRTIEDGQSIKEWTKTTKQAVVAGAGAIGLEMAFGLKEIGIDVTVVEMVPQV
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCEEHHHHHHHH
FPRALDPEMAKIVQEYLEENGIRIILEKPLGKIIGNEKVKAVIIGEEQIDTELVIMSTGV
CCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCCCCCCEEEEEECCC
RSNIELAKLAGCEIGRWAILTNNLMQTSIENIYAVGDCVEVIDAITGQNTLSPFGTTAVR
CCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QGKVAAKSIAGIDAESSPVLNSMVSKIGALEIGGTGMTETAAKMNGIDVVIGNAKALTRA
CCCHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHCCCEEEEECCCHHHHHE
RYYPGGEPIFIKLVCEKNSRRIIGCQIISKERVAERVDAMSIAISKKMTVDELLNQEFSY
ECCCCCCEEEEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
APPVSMVIDPLTFAAEDAFEKF
CCCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNVVIIGSGAGGLTTASNIKKYSANAKITILTEDKHIAYSPCAIPYVIGGEIEKFENIVM
CEEEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEECCCHHHHHHHHC
HTPKDYERKGIEVITESKVVDVVANQNIVIYEEKGIKKEISYEKLVIATGGTPFIPPIDG
CCCCCHHCCCCEEEECCEEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
VNLKGVFKVRTIEDGQSIKEWTKTTKQAVVAGAGAIGLEMAFGLKEIGIDVTVVEMVPQV
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCEEHHHHHHHH
FPRALDPEMAKIVQEYLEENGIRIILEKPLGKIIGNEKVKAVIIGEEQIDTELVIMSTGV
CCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCCCCCCEEEEEECCC
RSNIELAKLAGCEIGRWAILTNNLMQTSIENIYAVGDCVEVIDAITGQNTLSPFGTTAVR
CCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QGKVAAKSIAGIDAESSPVLNSMVSKIGALEIGGTGMTETAAKMNGIDVVIGNAKALTRA
CCCHHHHHHCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHCCCEEEEECCCHHHHHE
RYYPGGEPIFIKLVCEKNSRRIIGCQIISKERVAERVDAMSIAISKKMTVDELLNQEFSY
ECCCCCCEEEEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
APPVSMVIDPLTFAAEDAFEKF
CCCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]