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The map label for this gene is nadA [H]

Identifier: 150399308

GI number: 150399308

Start: 608049

End: 608966

Strand: Reverse

Name: nadA [H]

Synonym: Mevan_0556

Alternate gene names: 150399308

Gene position: 608966-608049 (Counterclockwise)

Preceding gene: 150399309

Following gene: 150399299

Centisome position: 35.4

GC content: 31.26

Gene sequence:

>918_bases
ATGAACATACTGGATAGGATAAATAAACTTAAAAAAGAGAAAAATGCAATAATTTTAGCACACAACTATCAGCCAGAAGA
AATTCAAAAAATTGCAGATATAATTGGCGATTCCTTAGAACTTTGTATTGCTGCAAAGGATACAAATAAAGATATAATTG
TATTTTGCGGTGTGGATTTTATGGCAGAAACTGCAAAAGTTTTAAATCCTGAAAAAAAAGTGTTAATTCCGGAAATTATT
GAAACTTACTGTCCAATGGCACGTGATCTTCCACCGGAAGTTATACTTAAAGAAAAGAAAAAACACCCAAATGCGAAAGT
AGTAATTTATGTAAATACGTTAGCATCTTCAAAGGCTCTTGCCGATGCAACGTGTACGTCTGCAAATGCCGATAAAGTAG
TAAATTCATTTGACGAAAAAGAAATTTTATTTGGCCCAGACAATAATTTAGGGTACTTTGTATCAAAAAGAACGGATAAA
AAGATAATTTTAGTGCCTGAAGGTGGACACTGTTATGTTCACAAAACTTTTACAATTGAAGACATTAATCGGGTTAAAAA
AGAATACCCAAACGCAGAAATCCTAATTCATCCTGAAAGTGACCCCGAAATTCAAGATTTAGCAGATCATGTAATGAGTA
CCGGTGGAATGGTAAAACACGTACTTAACTCGGAAAAAGAGGAGTTTGTAATAGGTACAGAAGTTGATATGATTACAAGA
ATAAAAATCGATTTAGAAAAGCTTGGAAAAACTAAAAAATTAATTCCACTAAGAAAAAATGCAATCTGTACGTCAATGAA
ACCGATTTCTTTAGAAAAGTTAGAAAAATGTCTTTTAGAAGAAAATTACGAGATAAATCTTTCAGAAGAAATAATTGAAA
ATGCAAAAAAGGCAATTAATAGAATGCTTTTGATTTAA

Upstream 100 bases:

>100_bases
TATAGCTTGGATAAAATTGCCGAAAAAATGGTTATCGAAGCCTTAAAAATTAAAAAAGAGATTATTAAATAATTTTAAGT
GAGATTAAAGGTGTATATTT

Downstream 100 bases:

>100_bases
TACTATATATTTTATTTTTCTATTACTTGATATTTGACTACATCGTCAGTTTCATAGAATTTTTCGGCTTTATAATAATT
GATATCGCCATTAGTATCTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNILDRINKLKKEKNAIILAHNYQPEEIQKIADIIGDSLELCIAAKDTNKDIIVFCGVDFMAETAKVLNPEKKVLIPEII
ETYCPMARDLPPEVILKEKKKHPNAKVVIYVNTLASSKALADATCTSANADKVVNSFDEKEILFGPDNNLGYFVSKRTDK
KIILVPEGGHCYVHKTFTIEDINRVKKEYPNAEILIHPESDPEIQDLADHVMSTGGMVKHVLNSEKEEFVIGTEVDMITR
IKIDLEKLGKTKKLIPLRKNAICTSMKPISLEKLEKCLLEENYEINLSEEIIENAKKAINRMLLI

Sequences:

>Translated_305_residues
MNILDRINKLKKEKNAIILAHNYQPEEIQKIADIIGDSLELCIAAKDTNKDIIVFCGVDFMAETAKVLNPEKKVLIPEII
ETYCPMARDLPPEVILKEKKKHPNAKVVIYVNTLASSKALADATCTSANADKVVNSFDEKEILFGPDNNLGYFVSKRTDK
KIILVPEGGHCYVHKTFTIEDINRVKKEYPNAEILIHPESDPEIQDLADHVMSTGGMVKHVLNSEKEEFVIGTEVDMITR
IKIDLEKLGKTKKLIPLRKNAICTSMKPISLEKLEKCLLEENYEINLSEEIIENAKKAINRMLLI
>Mature_305_residues
MNILDRINKLKKEKNAIILAHNYQPEEIQKIADIIGDSLELCIAAKDTNKDIIVFCGVDFMAETAKVLNPEKKVLIPEII
ETYCPMARDLPPEVILKEKKKHPNAKVVIYVNTLASSKALADATCTSANADKVVNSFDEKEILFGPDNNLGYFVSKRTDK
KIILVPEGGHCYVHKTFTIEDINRVKKEYPNAEILIHPESDPEIQDLADHVMSTGGMVKHVLNSEKEEFVIGTEVDMITR
IKIDLEKLGKTKKLIPLRKNAICTSMKPISLEKLEKCLLEENYEINLSEEIIENAKKAINRMLLI

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=312, Percent_Identity=32.3717948717949, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34437; Mature: 34437

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILDRINKLKKEKNAIILAHNYQPEEIQKIADIIGDSLELCIAAKDTNKDIIVFCGVDF
CCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCHH
MAETAKVLNPEKKVLIPEIIETYCPMARDLPPEVILKEKKKHPNAKVVIYVNTLASSKAL
HHHHHHHHCCCCCEEHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHH
ADATCTSANADKVVNSFDEKEILFGPDNNLGYFVSKRTDKKIILVPEGGHCYVHKTFTIE
HHHHCCCCCHHHHHHCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCEEEEEEEEEHH
DINRVKKEYPNAEILIHPESDPEIQDLADHVMSTGGMVKHVLNSEKEEFVIGTEVDMITR
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCEEEE
IKIDLEKLGKTKKLIPLRKNAICTSMKPISLEKLEKCLLEENYEINLSEEIIENAKKAIN
EEEEHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RMLLI
HHHCC
>Mature Secondary Structure
MNILDRINKLKKEKNAIILAHNYQPEEIQKIADIIGDSLELCIAAKDTNKDIIVFCGVDF
CCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCHH
MAETAKVLNPEKKVLIPEIIETYCPMARDLPPEVILKEKKKHPNAKVVIYVNTLASSKAL
HHHHHHHHCCCCCEEHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHH
ADATCTSANADKVVNSFDEKEILFGPDNNLGYFVSKRTDKKIILVPEGGHCYVHKTFTIE
HHHHCCCCCHHHHHHCCCCCEEEECCCCCCEEEEEECCCCEEEEEECCCEEEEEEEEEHH
DINRVKKEYPNAEILIHPESDPEIQDLADHVMSTGGMVKHVLNSEKEEFVIGTEVDMITR
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCEEEE
IKIDLEKLGKTKKLIPLRKNAICTSMKPISLEKLEKCLLEENYEINLSEEIIENAKKAIN
EEEEHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RMLLI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]