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The map label for this gene is cbiT

Identifier: 150399288

GI number: 150399288

Start: 591489

End: 592031

Strand: Reverse

Name: cbiT

Synonym: Mevan_0536

Alternate gene names: 150399288

Gene position: 592031-591489 (Counterclockwise)

Preceding gene: 150399290

Following gene: 150399287

Centisome position: 34.42

GC content: 29.28

Gene sequence:

>543_bases
ATGATAAAAGACAGCGAATTTTATAGGCTTGATGGAGTTCCCATAACAAAAGAGGAAATAAGGGCAATAAGTGTTGAAAA
ATTAAACATCTGTCCTGAAGATATTATTTTAGACATAGGATGTGGAAGCGGGGGAATGACTGTTGAAATTTCTAAAAGAT
GTAAATTTGTTTATGCAGTAGATGGCTCAAAAGATGCTATCGATACGACCCTAAAAAACATGGATAAATTTAACGTAAAA
AACTGTGAAGTTTATTTTGGGGATGCAAAAGATTTGATATCAAATTTTAAAGTAAATAAAGCTTTTATTGGGGGTACCCA
AAATATAGAATCAGTTATTGAAAAATTAAATGAAAAGAATGTTAGAAATATAGTAATAAATACAATCGTGCTTGAAAATT
CAGTAAAAGTTATTCAAATTTTAGAAAGACTTAATTTTTCAATCGAAGTTATCAGTGTTCTAATTTCATATGGTAAACGG
ATAAGTTCTGGCCATATGATGCTTTCTAAAAACCCGATAACTATAATTACCGCTAAAAAATGA

Upstream 100 bases:

>100_bases
AAAACTGTTACATTATTTAATAATTAAGCCCTTTATATAATTAAGTAATATGACTATTTATAACTTGTTAATAATATAAA
AGATGCTATAAGATGGTAAA

Downstream 100 bases:

>100_bases
GTTTCTAGCCAAAATAAAATACCAAAGTTTTTTAGGCATTTACATTTAATTTAGATATATTTAATAAATATAAAAAATAG
ATTTATATTGTTGTTAAATT

Product: precorrin-6Y C5,15-methyltransferase subunit CbiT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAVDGSKDAIDTTLKNMDKFNVK
NCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKNVRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKR
ISSGHMMLSKNPITIITAKK

Sequences:

>Translated_180_residues
MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAVDGSKDAIDTTLKNMDKFNVK
NCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKNVRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKR
ISSGHMMLSKNPITIITAKK
>Mature_180_residues
MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAVDGSKDAIDTTLKNMDKFNVK
NCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKNVRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKR
ISSGHMMLSKNPITIITAKK

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIT_METVS (A6UPM1)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323055.1
- ProteinModelPortal:   A6UPM1
- SMR:   A6UPM1
- STRING:   A6UPM1
- GeneID:   5325897
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0536
- eggNOG:   arNOG09110
- HOGENOM:   HBG553505
- OMA:   IRAVSIG
- ProtClustDB:   CLSK876165
- HAMAP:   MF_00786
- InterPro:   IPR014008
- InterPro:   IPR003358
- TIGRFAMs:   TIGR02469

Pfam domain/function: PF02390 Methyltransf_4

EC number: 1.-.-.-

Molecular weight: Translated: 20109; Mature: 20109

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: BINDING 16-16 BINDING 61-61 BINDING 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAV
CCCCCCEEEECCCCCCHHHHHEECEEEECCCCCCEEEEEECCCCCEEEEEECCEEEEEEE
DGSKDAIDTTLKNMDKFNVKNCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKN
CCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCC
VRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKRISSGHMMLSKNPITIITAKK
CCEEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECC
>Mature Secondary Structure
MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAV
CCCCCCEEEECCCCCCHHHHHEECEEEECCCCCCEEEEEECCCCCEEEEEECCEEEEEEE
DGSKDAIDTTLKNMDKFNVKNCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKN
CCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCC
VRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKRISSGHMMLSKNPITIITAKK
CCEEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA