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The map label for this gene is aroA

Identifier: 150399272

GI number: 150399272

Start: 571768

End: 573057

Strand: Reverse

Name: aroA

Synonym: Mevan_0520

Alternate gene names: 150399272

Gene position: 573057-571768 (Counterclockwise)

Preceding gene: 150399281

Following gene: 150399271

Centisome position: 33.32

GC content: 34.65

Gene sequence:

>1290_bases
GTGCTTATCGTTAAAAGGACATCGGAAGTAAAAGGTATTATAAATGCCCCTCCATCAAAGTCGTACACACATAGAGCAGT
AATTTCTGCATCCCTTGCAAATGGGCTATCTATTTTAAAAAATCCATTAAACGGTGCAGACTGTTTATCTTCAGCACATG
CATGTAGAATGCTTGGTGCAGAAATTACAAATGAGGTCGAAAAATGGACAATAATCGGGTCTAAATTAAAAGTTCCAGAT
AATATTATTGATATCGGGAACAGTGGAACTACTTTACGGATTATAACTGGAATTTCTTCCCAAATTCCTGATGGATATGC
CGTAATTACAGGGGATGATTCAATTAGGAAAAGGCCAATGCAACCGCTACTTGATGCATTAAAACAGCTTGGAATAGAAA
GTTTTTCAACAAGAAACAACGGAATTGCACCAATTATTGTGAAAGCAGGAAAAATTACAAGCAATTCTGTTAAAATACGG
GGTGACATGAGTTCTCAATTTATAACCTCGCTCATGATGACATTACCATTTAGTGAAACGGATTCGGAAATTATTTTGAC
GACCCCTTTAAAATCTGAACCGTATTTAAACATTACAATAGACGTTTTAGATAAATTTGGGGTAAAAATTGAAAAAATAG
TGGAAGAAAATAAAACCGGATATAAAATTAAAGGAAAACAAAGTTACCGTCCTTGTGAATATACTATTGAAGGTGATTAT
TCTTCTGCGTCATATTTAATTGCAACAGGGGTTTTATTAAATTCCGATATTGAAGTAAAGAATGTATTTAAGAATTCAAA
GCAAGGCGACCGAGAAATAATAGAAATAGTTAAGAAAATGGGTGCAGACGTAGAAATAAACGAAAATAACGTTAAAATAA
AAGGCCCTTATAATTTGAAAGGGATTGAAATAGATGTAACCAATATTCCCGATTTAGTCCCCACAATTGCAGTTTTAGGG
TGTTTTGCCGAAGGAAAAACGGTAGTTTACAACGGTGAACACGTAAGACTTAAAGAATGCGATAGATTAAACGCATGTGC
AGTTGAACTTTCAAAAATGGGTGCAGACATCGAAGAAAAACCCGATGGGCTTATAATTACTGGCACACATAAACTAACCG
GTTCAAAACTTAAAACTCATGATGATCACAGGCTTGTAATGGCATTTACTATTGCAGGAATGCTTGCAGATGGAGAAACT
GTAATTGAAGGTGAAGAATCGGTTAAAATATCGTTTCCCGATTTTGTAGATAAAATGAAATCAATTGGATGCAATATCGA
AGTAATTTAG

Upstream 100 bases:

>100_bases
ACATTCAATATATTTTAAATGGCGGTAATTTTTAATATTTGGATAGTTTGATATACTTTTCAGATAATTATGAAATTATT
CGCAAATTCACGGTGATTTA

Downstream 100 bases:

>100_bases
GGTATGAATTAATTAAATTTTTAGATTTTTAACTATTTAAAATATTAATTAACTTCTAAAGGTGGTTTTATGGATAAATT
TGGGGAATTTTTAGAATATT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLIVKRTSEVKGIINAPPSKSYTHRAVISASLANGLSILKNPLNGADCLSSAHACRMLGAEITNEVEKWTIIGSKLKVPD
NIIDIGNSGTTLRIITGISSQIPDGYAVITGDDSIRKRPMQPLLDALKQLGIESFSTRNNGIAPIIVKAGKITSNSVKIR
GDMSSQFITSLMMTLPFSETDSEIILTTPLKSEPYLNITIDVLDKFGVKIEKIVEENKTGYKIKGKQSYRPCEYTIEGDY
SSASYLIATGVLLNSDIEVKNVFKNSKQGDREIIEIVKKMGADVEINENNVKIKGPYNLKGIEIDVTNIPDLVPTIAVLG
CFAEGKTVVYNGEHVRLKECDRLNACAVELSKMGADIEEKPDGLIITGTHKLTGSKLKTHDDHRLVMAFTIAGMLADGET
VIEGEESVKISFPDFVDKMKSIGCNIEVI

Sequences:

>Translated_429_residues
MLIVKRTSEVKGIINAPPSKSYTHRAVISASLANGLSILKNPLNGADCLSSAHACRMLGAEITNEVEKWTIIGSKLKVPD
NIIDIGNSGTTLRIITGISSQIPDGYAVITGDDSIRKRPMQPLLDALKQLGIESFSTRNNGIAPIIVKAGKITSNSVKIR
GDMSSQFITSLMMTLPFSETDSEIILTTPLKSEPYLNITIDVLDKFGVKIEKIVEENKTGYKIKGKQSYRPCEYTIEGDY
SSASYLIATGVLLNSDIEVKNVFKNSKQGDREIIEIVKKMGADVEINENNVKIKGPYNLKGIEIDVTNIPDLVPTIAVLG
CFAEGKTVVYNGEHVRLKECDRLNACAVELSKMGADIEEKPDGLIITGTHKLTGSKLKTHDDHRLVMAFTIAGMLADGET
VIEGEESVKISFPDFVDKMKSIGCNIEVI
>Mature_429_residues
MLIVKRTSEVKGIINAPPSKSYTHRAVISASLANGLSILKNPLNGADCLSSAHACRMLGAEITNEVEKWTIIGSKLKVPD
NIIDIGNSGTTLRIITGISSQIPDGYAVITGDDSIRKRPMQPLLDALKQLGIESFSTRNNGIAPIIVKAGKITSNSVKIR
GDMSSQFITSLMMTLPFSETDSEIILTTPLKSEPYLNITIDVLDKFGVKIEKIVEENKTGYKIKGKQSYRPCEYTIEGDY
SSASYLIATGVLLNSDIEVKNVFKNSKQGDREIIEIVKKMGADVEINENNVKIKGPYNLKGIEIDVTNIPDLVPTIAVLG
CFAEGKTVVYNGEHVRLKECDRLNACAVELSKMGADIEEKPDGLIITGTHKLTGSKLKTHDDHRLVMAFTIAGMLADGET
VIEGEESVKISFPDFVDKMKSIGCNIEVI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=432, Percent_Identity=33.5648148148148, Blast_Score=216, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6320332, Length=425, Percent_Identity=29.4117647058824, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_METVS (A6UPK5)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323039.1
- ProteinModelPortal:   A6UPK5
- SMR:   A6UPK5
- STRING:   A6UPK5
- GeneID:   5325721
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0520
- eggNOG:   arNOG05032
- HOGENOM:   HBG646626
- OMA:   SSQFITS
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46705; Mature: 46705

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVKRTSEVKGIINAPPSKSYTHRAVISASLANGLSILKNPLNGADCLSSAHACRMLGA
CEEEEECHHCCEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHH
EITNEVEKWTIIGSKLKVPDNIIDIGNSGTTLRIITGISSQIPDGYAVITGDDSIRKRPM
HHHCCHHEEEEECCEEECCCCEEECCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHCCH
QPLLDALKQLGIESFSTRNNGIAPIIVKAGKITSNSVKIRGDMSSQFITSLMMTLPFSET
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECEEECCCEEEEECCHHHHHHHHHHHCCCCCC
DSEIILTTPLKSEPYLNITIDVLDKFGVKIEKIVEENKTGYKIKGKQSYRPCEYTIEGDY
CCEEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHCCCCCEEEECCCCCCCEEEEEECCC
SSASYLIATGVLLNSDIEVKNVFKNSKQGDREIIEIVKKMGADVEINENNVKIKGPYNLK
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCEEEEECCCCEE
GIEIDVTNIPDLVPTIAVLGCFAEGKTVVYNGEHVRLKECDRLNACAVELSKMGADIEEK
EEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCC
PDGLIITGTHKLTGSKLKTHDDHRLVMAFTIAGMLADGETVIEGEESVKISFPDFVDKMK
CCCEEEEECCCCCCCCCCCCCCCEEEEEEEEHHHHCCCCEEEECCCEEEEECHHHHHHHH
SIGCNIEVI
HCCCCEEEC
>Mature Secondary Structure
MLIVKRTSEVKGIINAPPSKSYTHRAVISASLANGLSILKNPLNGADCLSSAHACRMLGA
CEEEEECHHCCEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHH
EITNEVEKWTIIGSKLKVPDNIIDIGNSGTTLRIITGISSQIPDGYAVITGDDSIRKRPM
HHHCCHHEEEEECCEEECCCCEEECCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHCCH
QPLLDALKQLGIESFSTRNNGIAPIIVKAGKITSNSVKIRGDMSSQFITSLMMTLPFSET
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECEEECCCEEEEECCHHHHHHHHHHHCCCCCC
DSEIILTTPLKSEPYLNITIDVLDKFGVKIEKIVEENKTGYKIKGKQSYRPCEYTIEGDY
CCEEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHCCCCCEEEECCCCCCCEEEEEECCC
SSASYLIATGVLLNSDIEVKNVFKNSKQGDREIIEIVKKMGADVEINENNVKIKGPYNLK
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCEEEEECCCCEE
GIEIDVTNIPDLVPTIAVLGCFAEGKTVVYNGEHVRLKECDRLNACAVELSKMGADIEEK
EEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCC
PDGLIITGTHKLTGSKLKTHDDHRLVMAFTIAGMLADGETVIEGEESVKISFPDFVDKMK
CCCEEEEECCCCCCCCCCCCCCCEEEEEEEEHHHHCCCCEEEECCCEEEEECHHHHHHHH
SIGCNIEVI
HCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA