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The map label for this gene is tktB [C]

Identifier: 150399192

GI number: 150399192

Start: 491860

End: 492687

Strand: Reverse

Name: tktB [C]

Synonym: Mevan_0440

Alternate gene names: 150399192

Gene position: 492687-491860 (Counterclockwise)

Preceding gene: 150399195

Following gene: 150399191

Centisome position: 28.64

GC content: 34.9

Gene sequence:

>828_bases
ATGAAATGTAACAAACCTATGGATTATAAGCAGCTAAGTGAAAAATCAAAGGCATTGCGACACGATATCGTTAAAATGAT
AGGGATTGCAGAGTCTGGACATCCTGGTGGCTCACTTTCAGCAATCGATATTATTGTATCATTATTTTATAATATAATGA
AATTCGATTGTAATAATCCAGAAATGCAATATAGGGATAGGTTTATTTTAAGTAAGGGGCACGCATGTCCCGCATTATAT
GTTACACTTGCAGATTTGGATTATTTTAAAAGGGAAGAGCTTTGGAAATTAAGGCAACTTGGGGCACTTTTACAGGGGCA
CCCGACAATTGAAATCCCGGGTGTTGAAGTAAATACTGGCTCTCTTGGACAGGGATTTTCGTCTTCAGTTGGAGTTGCAA
TCGGCTGTAAATTAAATAATTATGAAAATTACGTTTTTGTATTACTTGGAGATGGGGAGTGTCAGGAAGGCCAAATATGG
GAAGCTTCAATGGCTGCATCACATTACAAACTTGATAACCTCATAGGCTTTGTTGATAGAAATAAACTCCAAATTGACGG
ATGTACTGAAGATGTAATGTGTTTAGGCGATTTAAAAGCTAAATTTAACGCATTTGGTTTTGATGTATTTGAAATTGATG
GCCACAATTACGAAGAAATTATTAAAACTGTAGAAAATGCAAAATTGATGAAAAATGGAAAGCCAAAAATGATTATTGCA
AATACTATAAAAGGAAAAGGCGTATCTTTCATGGAAAATAATGTGGGATTCCACGGAAAAGCACCAAATAAAGAAGAACT
AAAAAAAGCACTTACAGAACTCGAATAA

Upstream 100 bases:

>100_bases
GTGCAAGTATTATAAATATTAGGCAATTATTTTATTTTTAGCACTTGTTTTTCTGTTAATATTAAAGTAACTTAGAAAGG
ATATTTATTTTGGTGAAAAA

Downstream 100 bases:

>100_bases
ATTTTTCTAATAATTATGTAATACTTAAAAACGGTGAAATAAATGGTAATGATTGGTGCATCAATTCTTTCTGCGGATTA
TGGAAACATGAGTGAGGAAG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKCNKPMDYKQLSEKSKALRHDIVKMIGIAESGHPGGSLSAIDIIVSLFYNIMKFDCNNPEMQYRDRFILSKGHACPALY
VTLADLDYFKREELWKLRQLGALLQGHPTIEIPGVEVNTGSLGQGFSSSVGVAIGCKLNNYENYVFVLLGDGECQEGQIW
EASMAASHYKLDNLIGFVDRNKLQIDGCTEDVMCLGDLKAKFNAFGFDVFEIDGHNYEEIIKTVENAKLMKNGKPKMIIA
NTIKGKGVSFMENNVGFHGKAPNKEELKKALTELE

Sequences:

>Translated_275_residues
MKCNKPMDYKQLSEKSKALRHDIVKMIGIAESGHPGGSLSAIDIIVSLFYNIMKFDCNNPEMQYRDRFILSKGHACPALY
VTLADLDYFKREELWKLRQLGALLQGHPTIEIPGVEVNTGSLGQGFSSSVGVAIGCKLNNYENYVFVLLGDGECQEGQIW
EASMAASHYKLDNLIGFVDRNKLQIDGCTEDVMCLGDLKAKFNAFGFDVFEIDGHNYEEIIKTVENAKLMKNGKPKMIIA
NTIKGKGVSFMENNVGFHGKAPNKEELKKALTELE
>Mature_275_residues
MKCNKPMDYKQLSEKSKALRHDIVKMIGIAESGHPGGSLSAIDIIVSLFYNIMKFDCNNPEMQYRDRFILSKGHACPALY
VTLADLDYFKREELWKLRQLGALLQGHPTIEIPGVEVNTGSLGQGFSSSVGVAIGCKLNNYENYVFVLLGDGECQEGQIW
EASMAASHYKLDNLIGFVDRNKLQIDGCTEDVMCLGDLKAKFNAFGFDVFEIDGHNYEEIIKTVENAKLMKNGKPKMIIA
NTIKGKGVSFMENNVGFHGKAPNKEELKKALTELE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=266, Percent_Identity=36.0902255639098, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4507521, Length=266, Percent_Identity=36.0902255639098, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI133778974, Length=264, Percent_Identity=36.7424242424242, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI225637459, Length=264, Percent_Identity=29.1666666666667, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI225637461, Length=233, Percent_Identity=29.6137339055794, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI225637463, Length=228, Percent_Identity=29.8245614035088, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1788808, Length=281, Percent_Identity=35.9430604982206, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI48994911, Length=262, Percent_Identity=35.4961832061069, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539652, Length=250, Percent_Identity=41.6, Blast_Score=203, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6325331, Length=261, Percent_Identity=37.9310344827586, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319593, Length=270, Percent_Identity=35.9259259259259, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45551847, Length=281, Percent_Identity=36.6548042704626, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI45550715, Length=281, Percent_Identity=36.6548042704626, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24666278, Length=238, Percent_Identity=37.8151260504202, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24645119, Length=229, Percent_Identity=38.4279475982533, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30641; Mature: 30641

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCNKPMDYKQLSEKSKALRHDIVKMIGIAESGHPGGSLSAIDIIVSLFYNIMKFDCNNP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
EMQYRDRFILSKGHACPALYVTLADLDYFKREELWKLRQLGALLQGHPTIEIPGVEVNTG
CHHHHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEECCC
SLGQGFSSSVGVAIGCKLNNYENYVFVLLGDGECQEGQIWEASMAASHYKLDNLIGFVDR
CCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
NKLQIDGCTEDVMCLGDLKAKFNAFGFDVFEIDGHNYEEIIKTVENAKLMKNGKPKMIIA
CEEEECCCCCHHEEHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
NTIKGKGVSFMENNVGFHGKAPNKEELKKALTELE
ECCCCCCCEEHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKCNKPMDYKQLSEKSKALRHDIVKMIGIAESGHPGGSLSAIDIIVSLFYNIMKFDCNNP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
EMQYRDRFILSKGHACPALYVTLADLDYFKREELWKLRQLGALLQGHPTIEIPGVEVNTG
CHHHHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEECCC
SLGQGFSSSVGVAIGCKLNNYENYVFVLLGDGECQEGQIWEASMAASHYKLDNLIGFVDR
CCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
NKLQIDGCTEDVMCLGDLKAKFNAFGFDVFEIDGHNYEEIIKTVENAKLMKNGKPKMIIA
CEEEECCCCCHHEEHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
NTIKGKGVSFMENNVGFHGKAPNKEELKKALTELE
ECCCCCCCEEHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]