Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 150399153

GI number: 150399153

Start: 453070

End: 454410

Strand: Reverse

Name: glmM

Synonym: Mevan_0400

Alternate gene names: 150399153

Gene position: 454410-453070 (Counterclockwise)

Preceding gene: 150399158

Following gene: 150399152

Centisome position: 26.42

GC content: 32.96

Gene sequence:

>1341_bases
TTGAAACTTTTTGGAACTTCTGGAATTAGGATGAAAAATTTAGACCCTTTAATTGCATACAAGGTAGGTTTTGCAATATC
TAAAAATTTTAAAAAGGCAGTAATTGGAAGAGACACGAGAACTACTGGAAATTTAATTGAAAGTGCAATTACAGCAGGAC
TTTTAAATGGGGGTTGTGATGTAACGATTTTAGGAATTGTTCCAACTCCCGTCTTGGGGTTTTCTGCAAAAAGCCATGAT
ATTGGAATTATGATTACGGCATCCCACAATCCGCCAGAATACAACGGGATAAAGCTATTTAATAATAACGGAACCTCTTT
TACGCCAAATCAAGAAGAATCTTTGGAAGAAATAATTGAAAAAAGCGATTTTTTAGACCCTTCATGGGACATTGTAGGAA
ATGTTTCAGAAGATAAAACTGCCGTTAAAAAGTATTTGGACTATATTTTAAGTAATATAAATATAAAAAAGAAATTTAAT
GTTGTTGTTGACTGTGCAAATGCTGCAGCATGCGGAATTTCACCAAATTTATTTACTAATGCAGGATGTAAGGTAATTTC
CGTAAATTCGCACTGTGATGGAAGGTTTGTTGGACGAATGCCTGAACCAAATGAAAAAAACCTTGTTGAAACAGTAGATA
TTGTAAAAGGACTTAATTTATCTGGAAGGGATTTTATCGGTATTGCACATGATGGCGATGCAGATAGGATGATTGCAATT
GATGAAATGGGAAGAGTAACTGATTTTGATAAACTTTTAGCTGCATTTTGTAAATATGTCGTTCAAAAAACAAATGCTAA
AAAAATCGTAACAACGGTTGACGCATCAATGGCAATTGAAGAATATTTGAAGGAGTTTGGAGCAGAAGTTATAAGAACAA
AAATTGGCGATGTTTCTGTTGCATATGAAATTGAAAAAACAGGTGCTATTTTTGGAGGGGAGCCTTCAGGAACTTGGATT
CATAAAAGCATTCATTTAACGCCTGATGGAATTCTTTCAGGACTTAGGGTCTTAGAAATGATGGAGTTTTATGATAAAAG
ACTATGCGAAATTATGGATGAAGTTCCTTCATACATTAATTTACGTGAAAAACTGCCATGTCCTGATGAATTAAAGAATA
AAGTTATGAAATATGTTTCAAAAGAAGGTAAATTATTATTTAAAAAAGAACCTGAAACTCTTGATGGGGTTAGATTTTCA
TTTGAAAATGGATGGATATTAATTAGGCCTTCAGGAACTGAAAGTTACATTAGAGTTAGAGTTGAAGCAAAAGATGAAAC
GTTTGCAAATGAACTGTTAAATAACGGAATTTCGCTTGTAAATAACGGAATTTTGAAATAA

Upstream 100 bases:

>100_bases
ATACCGATAAAAGAATATAAAGATTGAGTTTATTATTTTAACTTTTTGACTAGTTATTTAGTTTAATCAATTAATTAGTT
ATTAAGTATCGGGTGAAAAA

Downstream 100 bases:

>100_bases
GGGGGAAAATATGGATGCAGTAATATTATGTGCCGGAAGTGGAACAAGACTTTATCCTATAACCGAAAATCGTCCAAAAC
CAATGATCCCAATTGCGGGA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCDVTILGIVPTPVLGFSAKSHD
IGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIEKSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFN
VVVDCANAAACGISPNLFTNAGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAI
DEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSVAYEIEKTGAIFGGEPSGTWI
HKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYINLREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFS
FENGWILIRPSGTESYIRVRVEAKDETFANELLNNGISLVNNGILK

Sequences:

>Translated_446_residues
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCDVTILGIVPTPVLGFSAKSHD
IGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIEKSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFN
VVVDCANAAACGISPNLFTNAGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAI
DEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSVAYEIEKTGAIFGGEPSGTWI
HKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYINLREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFS
FENGWILIRPSGTESYIRVRVEAKDETFANELLNNGISLVNNGILK
>Mature_446_residues
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCDVTILGIVPTPVLGFSAKSHD
IGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIEKSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFN
VVVDCANAAACGISPNLFTNAGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAI
DEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSVAYEIEKTGAIFGGEPSGTWI
HKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYINLREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFS
FENGWILIRPSGTESYIRVRVEAKDETFANELLNNGISLVNNGILK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=461, Percent_Identity=31.6702819956616, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788361, Length=442, Percent_Identity=26.6968325791855, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_METVS (A6UP86)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001322920.1
- ProteinModelPortal:   A6UP86
- SMR:   A6UP86
- STRING:   A6UP86
- GeneID:   5325641
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0400
- eggNOG:   arNOG04251
- HOGENOM:   HBG644964
- OMA:   CMITASH
- ProtClustDB:   CLSK2517686
- HAMAP:   MF_01554_A
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49196; Mature: 49196

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00710 PGM_PMM; PS00018 EF_HAND_1

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCD
CCEECCCCCEECCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
VTILGIVPTPVLGFSAKSHDIGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIE
EEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
KSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFNVVVDCANAAACGISPNLFTN
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCC
AGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAI
CCEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEE
DEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSV
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AYEIEKTGAIFGGEPSGTWIHKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYIN
EEEEECCCEEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFSFENGWILIRPSGTESYIRVR
HHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCCEEEEEE
VEAKDETFANELLNNGISLVNNGILK
EECCCHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCD
CCEECCCCCEECCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
VTILGIVPTPVLGFSAKSHDIGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIE
EEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
KSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFNVVVDCANAAACGISPNLFTN
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCC
AGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAI
CCEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEE
DEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSV
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AYEIEKTGAIFGGEPSGTWIHKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYIN
EEEEECCCEEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFSFENGWILIRPSGTESYIRVR
HHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCCEEEEEE
VEAKDETFANELLNNGISLVNNGILK
EECCCHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA